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The Division of Neuroimmunology at the Center for Brain Research explores the cellular and molecular dynamics underlying interactions between immune and nervous systems in a wide range of settings, including progression of neuroinflammatory disorders, development of the nervous system, the formation of sensory organs, and tumorigenesis. Our laboratories investigate the mechanisms of cell-cell communication, stemness, fate determination, and the interplay between immune cells, neurons, glia and their molecular environments, with implications for understanding both normal development and disease states.
Prof. Igor Adameyko is leading the Division of Neuroimmunology since 2020 with a particular focus on strengthening the cutting-edge methodological approaches. Over the recent years, the Division has become a leader in integrating frontier technologies like single-cell RNA sequencing, clonal barcoding, spatial transcriptomics, advanced microscopy, genetic lineage tracing, computational biology and machine learning to address fundamental questions in neurobiology and neuroimmunology. The Division is enriched by active collaborations with national and international research institutions, such as Harvard Medical School, Altos, Caltech, Karolinska Institutet and many more. We are a part of Medical Neuroscience Cluster and Cluster of Excellence in Neurobiology.
In addition to the laboratory of Igor Adameyko, which studies fundamental aspects of neurodevelopment, the Division includes the laboratories of Jan Bauer (mechanisms of inflammatory diseases of the CNS), Monika Bradl (autoimmune mechanisms and pathological processes in neuroimmunological diseases, especially neuromyelitis optica), Maria Eleni Kastriti (development of endocrine system and interactions with nervous and immune systems).
The laboratories of our Division are funded by national and international competitive programs, such as ERC Consolidator, ERC Synergy and Emerging Fields (Austrian “Excellence Program”). Our Division supports independent and collaborative research projects, encouraging the scientific freedom of its researchers while ensuring the integration of multidisciplinary expertise inside the Division. We strive to create a collegial, inclusive, and dynamic environment, attracting a diverse group of international scientists who are driven to push the boundaries of knowledge in neuroimmunology, neurobiology, computational methods and beyond.