Latest Publications

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• Silberbauer L, Eggerstorfer B, Michenthaler P, Reichel S, Stimpfl T, Vanicek T, Naderi-Heiden A, Kasper S, Lanzenberger R, Gryglewski G (2026) Oral ketamine for the treatment of major depressive and bipolar disorder, a randomized controlled trial and meta-analysis J Affect Disord, 394: 120466
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• Müller T, Künzi A, Heitlinger E, Krämer B, von Känel R, Hättenschwiler J, Hilpert M, Imboden C, Holsboer-Trachsler E, Hatzinger M, Kasper S, Bandelow B, Seifritz E (2025) Comparative efficacy and acceptability of anxiolytic drugs for the treatment of anxiety disorders: a systematic review and network meta-analysis Eur Arch Psychiatry Clin Neurosci,
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• Serretti A, Souery D, Kasper S, Zohar J, Montgomery S, Ferentinos P, Rujescu D, Ferri R, Fanelli G, Fabbri C, Zanardi R, Benedetti F, Baune B, Mendlewicz J (2025) Schizophrenia Genetics Modulates Clinical Depressive Features Am. J. Med. Genet. B Neuropsychiatr. Genet. ,
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• Serretti A, Souery D, Kasper S, Bartova L, Zohar J, Montgomery S, Ferentinos P, Rujescu D, Ferri R, Fanelli G, Zanardi R, Benedetti F, Baune B, Mendlewicz J (2025) Polygenic liability to C-reactive protein defines immunometabolic depression phenotypes and influences antidepressant therapeutic outcomes Genomic Psychiatry , 1 (5): 30-35
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• Kasper S (2025) Siegfried Kasper: The importance of back-translation of clinical findings to basic science Brain Medicine, 1 (5): 30-33
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• Wegener G, Lerer B, Frazer A, Grace A, Ikeda K, Gobbi G, Young A, Zohar J, Blier P, Kasper S, Krystal J, Yamawaki S, Philips A, Möller H, Belmaker R, Atwoli L, Nutt D, Harvey B, Seedat S, Berk M, Emsley R (2025) In Memoriam: Professor Dan J. Stein (1962-2025) – A Global Pioneer with an African Heart Int. J. Neuropsychopharmacol.,
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• Šulcová M, Dumková J, Hutečková B, Kavková M, Parobková V, Zahradníček O, Křivánek J, Adameyko I, Kaiser J, Zikmund T, Tucker A, Buchtová M (2025) Tooth–bone attachment tissue is produced by cells with a mixture of odontoblastic and osteoblastic features in reptiles J. Anat., : Nov 19. doi: 10.1111/joa.70059. Online ahead of print.
• Jász A, Biró L, Buday Z, Király B, Szalárdy O, Horváth K, Komlósi G, Bódizs R, Kovács K, Diana M, Hangya B, Acsády L (2025) Persistently increased post-stress activity of paraventricular thalamic neurons is essential for the emergence of stress-induced alterations in behaviour PLoS Biol., 23 (1): e3002962
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• Kajtor M, Billes V, Király B, Karkusova P, Kovács T, Stabb H, Sviatkó K, Vizi A, Ujvári E, Balázsfi D, Seidenbecher S, Kvitsiani D, Vellai T, Hangya B (2025) Altered reactivity to threatening stimuli in Drosophila models of Parkinson’s disease, revealed by a trial-based assay eLife, 13
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• Schlingloff D, Freund T, Hangya B, Gulyás A (2025) Collapsing Perisomatic Inhibition Leads to Epileptic Fast-Ripple Oscillations Caused by Pseudosynchronous Firing of CA3 Pyramidal Neurons J. Neurosci., 45 (46): e0500252025
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• Schlosser G, Murgaš M, Godbersen G, Reichel S, Silberbauer L, Nics L, Winkler D, Stimpfl T, Hacker M, Kasper S, Rujescu D, Lanzenberger R, Spies M (2025) Human in vivo assessment of ketamine binding of the serotonin transporter—follow up at a higher dose Front Neurosci, 19: 651016
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• Lázár E, Mauron R, Andrusivová ?, Foyer J, He M, Larsson L, Shakari N, Salas S, Avenel C, Sariyar S, Hansen J, Vicari M, Czarnewski P, Braun E, Li X, Bergmann O, Sylvén C, Lundberg E, Linnarsson S, Nilsson M, Sundström E, Adameyko I, Lundeberg J (2025) Spatiotemporal gene expression and cellular dynamics of the developing human heart Nature Genetics, : Oct 29. doi: 10.1038/s41588-025-02352-6. Online ahead of print.
• Abondio P, Fanelli G, Baldini V, Bacalini M, Kasper S, Zohar J, Souery D, Montgomery S, Albani D, Forloni G, Ferentinos P, Rujescu D, Mendlewicz J, Serretti A, Monteleone A, Grassi L, Atti A, Menchetti M, Fabbri C, De Ronchi D (2025) Polygenic predisposition to transdiagnostic symptom dimensions and treatment outcomes across psychiatric disorders Prog Neuropsychopharmacol Biol Psychiatry, 142: 111512
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• Serretti A, Kasper S, Bartova L, Zohar J, Souery D, Montgomery S, Ferentinos P, Rujescu D, Kautzky A, Attanasio F, Zanardi R, Fabbri C, Baune B, Ferri R, Mendlewicz J (2025) Clinical predictors of treatment resistant depression Eur Neuropsychopharmacol, 98: 26-34
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• Preindl K, Stimpfl T, Koellensperger G, Dorninger F, Berger J, Wiesinger C (2025) A fast GC–MS/MS method for the simultaneous measurement of key metabolites of peroxisomal beta-oxidation and ether lipid biosynthesis in human fibroblasts J Chromatography B, 1267: 124806
• White I, Luca A, Luca M, Bartova L, Kasper S, Zohar J, Souery D, Montgomery S, Ferentinos P, Rujescu D, Mendlewicz J, Zanardi R, Ferri R, Lanza G, Rodolico A, Signorelli M, Serretti A (2025) The impact of depression on functioning: Relation to medication response and other predictors Psychiat Res, 351: 116599
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• Luca A, Luca M, Kasper S, Zohar J, Souery D, Montgomery S, Ferentinos P, Rujescu D, Mendlewicz J, Zanardi R, Ferri R, Lanuzza B, Pecorino B, Baune B, Fanelli G, Fabbri C, Serretti A (2025) Mild motor signs and depression: more than just medication side effects? Eur Arch Psychiatry Clin Neurosci,
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• Kasper S, Incalzi R, Bozzali M, Morgado P, Siwek M (2025) Managing depression in the elderly: real-world clinical considerations and perspectives Int Clin Psychopharmacol, 40: 339-352
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• Ada S, Klinger L, Teuchmann H, Mussetto V, Hadschieff V, Kronschläger M, Siegert A, Trofimova L, Holzinger R, Kurija D, Drdla-Schutting R (2025) Astrocytogenic bidirectional plasticity at spinal nociceptive synapses regulates acute nociceptive processing PAIN,
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• Kautzky A, Bartova L, Dold M, Souery D, Montgomery S, Zohar J, Mendlewicz J, Fabbri C, Serretti A, Tretiakov E, Rujescu D, Harkany T, Kasper S (2025) Symptom networks in major depressive disorder and treatment response: special focus on TRD Eur Psychiatry, 68 (1): e61
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• Qu T, Chacón B, Faure L, Losa M, Hernández-Martínez R, Robinson K, Jones A, Lisgo S, De Anda J, Risolino M, Panagiotakos G, Leslie-Clarkson E, Adameyko I, Selleri L (2025) Cell Cycle Arrest of a ‘Zippering’ Epithelial Cell Cluster Shapes the Face and is Disrupted in Craniofacial Disorders bioRxiv, : Jul 30:2025.07.28.667310. doi: 10.1101/2025.07.28.667310
• DiGiovanni L, Khroud P, Carmichael R, Schrader T, Gill S, Germain K, Jomphe R, Wiesinger C, Boutry M, Kamoshita M, Snider D, Stubbings G, Hua R, Garber N, Hacker C, Rutenberg A, Melnyk R, Berger J, Schrader M, Raught B, Kim P (2025) ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox Science, 389 (6756): 157-162
• Fatieieva Y, Galimullina R, Isaev S, Klimovich A, Lemaire L, Adameyko I (2025) Melanocytes and photosensory organs share a common ancestry that illuminates the origins of the neural crest Commun Biol, 8 (1): 1092
• Murgaš M, Milz C, Stöhrmann P, Unterholzner J, Nics L, Kranz G, Hahn A, Hacker M, Kasper S, Lanzenberger R, Godbersen G (2025) In vivo serotonin 1A receptor distribution in treatment-resistant depression Transl Psychiat, 15
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• Klinger L, Siegert A, Holzinger R, Trofimova L, Ada S, Drdla-Schutting R (2025) An evaluation of distinct adeno-associated virus vector strategies for driving transgene expression in spinal inhibitory neurons of the rat Front Neurosci, 19
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• Valenti O, Rekawek K, Wieser S, Bulut H, Scholze P, Boehm S (2025) Plasticity of ventral tegmental area disturbance during abstinence after repeated amphetamine exposure: restoration by selective activation of group II metabotropic glutamate receptors Front. Pharmacol., 16: 1534101
• Erickson A, Isaev S, Artemov A, He J, Semsch B, Murtazina A, Sun J, Mangold K, Chalou A, Frisen J, Ratz M, Andersson E, Kharchenko P, Adameyko I (2025) Unbiased profiling of multipotency landscapes reveals spatial modulators of clonal fate biases bioRxiv, Jun 6:11.15.623687: Preprint
• Mair K, Guggenberger V, Verdú de Juan L, Köck U, Lassmann H, Liblau R, Bien C, Bauer J (2025) The dynamics of brain T cell populations during the course of rasmussen encephalitis: from expansion to exhaustion J Neuroinflammation, 22 (1): 155
• Oliva V, Possidente C, Fanelli G, Domschke K, Minelli A, Gennarelli M, Martini P, Bortolomasi M, Squassina A, Pisanu C, Kasper S, Zohar J, Souery D, Montgomery S, Albani D, Forloni G, Ferentinos P, Rujescu D, Mendlewicz J, Baune B, Vieta E, Serretti A, Fabbri C (2025) Predicted plasma proteomics from genetic scores and treatment outcomes in major depression: a meta-analysis Eur Neuropsychopharmacol, 96: 17-27
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• Boström J, Zapaɫa M, Adameyko I (2025) Boosting multiplexing capabilities for error-robust spatial transcriptomic methods using a set exchange approach Sci Adv, 11 (18): Epub ahead of print 2025 May 2.
• Arenillas C, Celada L, Ruiz-Cantador J, Calsina B, Datta D, García-Galea E, Fasani R, Moreno-Cárdenas A, Alba-Linares J, Miranda-Barrio B, Martínez-Montes M, Alvarez-Escola C, Lecumberri B, González García A, Regojo Zapata R, Pozo-Kreilinger J, Iglesias C, Dwight T, Muir C, Oleaga A, Garrido-Lestache Rodríguez-Monte M, Del Cerro M, Martínez-Bendayán I, Álvarez-González E, Cubiella T, Lourenço D, A. Pereira M, Burnichon N, Buffet A, Broberg C, Dickson P, Fraga M, Llorente Pendás J, Rueda Soriano J, Buendía Fuentes F, Toledo S, Clifton-Bligh R, Dienstmann R, Villanueva J, Capdevila J, Gimenez-Roqueplo A, Bechmann N, Opotowsky A, Vaidya A, Bancos I, Weghorn D, Robledo M, Casteràs A, Dos-Subirà L, Adameyko I, Chiara M, Dahia P, Toledo R (2025) Convergent Genetic Adaptation in Human Tumors Developed Under Systemic Hypoxia and in Populations Living at High Altitudes Cancer Discov, : 15(5):1037-1062
• Pifl C, Wolf A, Elevado M, Scholze P (2025) α7‐Nicotinic Acetylcholine Receptor and Mutated α‐Synuclein Interact in Motor Behaviour and Nigrostriatal Dopamine—Findings With Potential Relevance for a Protective Effect of Cigarette Smoking and Parkinson's Disease Eur J Neurosci, 61 (6)
• Esser D, Müller-Miny L, Heming M, Paunovic M, van Duijn M, Abrante Cabrera L, Mair K, Strippel C, Räuber S, Dargvainiene J, Kovac S, Gross C, Fransen N, van Steenhoven R, Körtvélyessy P, Stenzel W, Höftberger R, Bindels E, Bien C, Wiendl H, Meuth S, Bauer J, Melzer N, Titulaer M, Leypoldt F, Meyer zu Hörste G, , de Vries J, Nagtzaam M, Franken S, Crijnen Y, Brenner J, van Steenhoven R, Kerstens J, de Bruijn M, Bastiaansen A, Hoogenboezem R, Veenbergen S, Smitt P (2025) Activated αβ T- and reduced mucosa-associated invariant T cells in LGI1- and CASPR2-encephalitis Brain, Mar 17:awaf096. doi: 10.1093/brain/awaf096. Online ahead of print.
• Luca M, Luca A, Messina A, Bartova L, Kasper S, Zohar J, Souery D, Montgomery S, Ferentinos P, Rujescu D, Mendlewicz J, Zanardi R, Ferri R, Lanuzza B, Benedetti F, Pecorino B, Baune B, Fanelli G, Fabbri C, Serretti A (2025) Specific symptomatology profile associated with treatment resistant depression: A multicentric study from the Group for the Study of Resistant Depression with a focus on sex J Affect Disord, 375: 249-255
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• Calabrò M, Fabbri C, Serretti A, Kasper S, Zohar J, Souery D, Montgomery S, Albani D, Forloni G, Ferentinos P, Rujescu D, Mendlewicz J, Colombo C, Zanardi R, De Ronchi D, Crisafulli C (2025) A machine learning approach to predict treatment efficacy and adverse effects in major depression using CYP2C19 and clinical-environmental predictors Psychiat Gen, 35 (2): 17-25
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• Lebedeva T, Boström J, Kremnyov S, Mörsdorf D, Niedermoser I, Genikhovich E, Hejnol A, Adameyko I, Genikhovich G (2025) β-catenin-driven endomesoderm specification is a Bilateria-specific novelty Nat Commun, 16 (1): 2476
• Spies M, Kasper S, Frey R, Baldinger-Melich P (2025) KET or ECT for treatment-resistant depression? Int J Psychiatry Clin Pract,
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• Kasper S, Incalzi RA, Bozzali M, Morgado P, Siwek M (2025) Managing Depression in the Elderly: Real-World Clinical Considerations and Perspectives on the Use of Trazodone. International Clinical Psychopharmacology Int Clin Psychopharmacol,
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• Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium. Electronic address: andrew.mcintosh@ed.ac.uk; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium including Kasper S (2025) Trans-ancestry genome-wide study of depression identifies 697 associations implicating cell types and pharmacotherapies Cell, 188: 640–652
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• Olgiati P, Kasper S, Zohar J, Souery D, Montgomery S, Ferentinos P, Rujescu D, Zanardi R, Fugger G, Ferri R, Tripodi M, Baune B, Fabbri C, Mendlewicz J, Serretti A (2025) Hypomanic symptoms in major depressive disorder: Prognostic impact and treatment issues J Affect Disord, 369: 1021-1030
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• Embaie B, Sarkar H, Alchahin A, Otte J, Olsen T, Tümmler C, Kameneva P, Artemov A, Akkuratova N, Adameyko I, Stukenborg J, Wickström M, Kogner P, Johnsen J, Mei S, Kharchenko P, Baryawno N (2025) Comparative Single-Cell Transcriptomics of Human Neuroblastoma and Preclinical Models Reveals Conservation of an Adrenergic Cell State Cancer Res, 85(6): 1015-1034
• Santambrogio A, Kemkem Y, Willis T, Berger I, Kastriti M, Faure L, Russell J, Lodge E, Yianni V, Kövér B, Oakey R, Altieri B, Bornstein S, Steenblock C, Adameyko I, Andoniadou C (2025) SOX2+ sustentacular cells are stem cells of the postnatal adrenal medulla Nat Commun, 16 (1): 16

• Steinschaden T, Faure L, Soldatov R, Adameyko I (2025) A competition model of multilineage priming and cell-fate decisions Cell Rep, 45 (1): Dec 31;45(1):116690. doi: 10.1016/j.celrep.2025.116690. Online ahead of print.
• Weinhofer I, Rommer P, Berger J (2025) Blood Biomarkers Reflecting Brain Pathology—From Common Grounds to Rare Frontiers J Inherit Metab Dis., 48 (3)
• Steriade C, Bauer J, Bien C (2025) Autoimmune encephalitis-associated epilepsy Nat Rev Neurol, : May 2. doi: 10.1038/s41582-025-01089-4. Online ahead of print.
• Carmichael R, Oeljeklaus S, Cruz-Zaragoza L, Kumar R, Bolton C, Islinger M, Kunze M, Pata J, Lismont C, Silva B, Kors S, Schrader M, Erdmann R (2025) Seventy years of peroxisome research: current advances and future perspectives Histochem Cell Biol, 163 (1)
• Kunze M, Malfatti F (2025) Towards a Conceptual Framework to Better Understand the Advantages and Limitations of Model Organisms Eur J Neurosci, 61 (7)
• Kamenev D, Kameneva P, Adameyko I (2025) The role of microheterogeneity in cell fate decisions in neural progenitors and neural crest Curr Opin Neurobiol, 92: 103031
• Bradl M, Yu Q, Takai Y (2025) The immunological processes behind aquaporin 4-antibody seropositive neuromyelitis optica spectrum disorders Semin Neurol, 78: 101945
• Powell J, Steinschaden T, Horowitz R, Song Y (2025) Calcium channels caught in peripheral glia’s tug-of-war on axon regeneration in Drosophila Neural Regen Research, 20 (2): 475-476