Univ.-Prof. Dr. Dan Rujescu
Focal points of interest
The Neurosurgical Clinic is running an intraoperative MRI Suite and has scanning time slots at the 7 Tesla Center of Excellence High-Field MRI of the MUV (Hangel) which provides whole brain MRSI (magneto-resonance spectroscopical imaging) for brain metabolites and neurotransmitters (Glumamin/Glutamat/GABA). Currently, glutamate imaging has already been established for the detection of epileptic brain conditions, GABA imaging is still not routinely established. Localisation and amount of GABA in the temporal lobes of epilepsy patients are planed to be established to allow a correlation with electrophysiological (Jonas), immunohistochemical (Klausberger) and genetic studies (Knöblich) in the same patients after harvesting the vital temporal/hippocampal tissue blocks for postsurgical studies on human tissue.
