Last year | Last five years | All
2024 Original Articles
- Szodorai E, Hevesi Z, Wagner L, Hökfelt T, Harkany T, Schnell R (2024) A hydrophobic groove in secretagogin allows for alternate interactions with SNAP-25 and syntaxin-4 in endocrine tissues Proc Natl Acad Sci USA, 121: e2309211121
- Harkany T, Tretiakov E, Varela L, Jarc J, Rebernik P, Newbold S, Keimpema E, Verkhratsky A, Horvath T, Romanov R (2024) Molecularly stratified hypothalamic astrocytes are cellular foci for obesity Res Sq,
- Harkany T, Tretiakov E, Varela L, Jarc J, Rebernik P, Newbold S, Keimpema E, Verkhratsky A, Horvath T, Romanov R (2024) Molecularly stratified hypothalamic astrocytes are cellular foci for obesity Nature, preprint
- Benevento M, Alpár A, Gundacker A, Afjehi L, Balueva K, Hevesi Z, Hanics J, Rehman S, Pollak D, Lubec G, Wulff P, Prevot V, Horvath T, Harkany T (2024) A brainstem–hypothalamus neuronal circuit reduces feeding upon heat exposure Nature, online
- Hevesi Z, Bakker J, Tretiakov E, Adori C, Raabgrund A, Barde S, Caramia M, Krausgruber T, Ladstätter S, Bock C, Hökfelt T, Harkany T (2024) Transient expression of the neuropeptide galanin modulates peripheral‑to‑central connectivity in the somatosensory thalamus during whisker development in mice Nat Commun, 15 : 2762
2023 Original Articles
- Caramia M, Romanov R, Sideromenos S, Hevesi Z, Zhao M, Krasniakova M, Xu Z, Harkany T, Hökfelt T (2023) Neuronal diversity of neuropeptide signaling, including galanin, in the mouse locus coeruleus Proc Natl Acad Sci USA, 120 (31)
- Romanov R, Harkany T (2023) Grabbing neuropeptide signals in the brain Science, 382 (6672): 764-765
| Weblink | - Cinquina V, Keimpema E, Pollak D, Harkany T (2023) Adverse effects of gestational ω‐3 and ω‐6 polyunsaturated fatty acid imbalance on the programming of fetal brain development Neuroendocrinology,
| https://pubmed.ncbi.nlm.nih.gov/37497857/ | - Petersen J, Englmaier L, Artemov A, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov E, Pajuelo Reguera D, Zeberg H, Kaucka M, Kastriti M, Krivanek J, Radaszkiewicz T, Gömöryová K, Knauth S, Potesil D, Zdrahal Z, Ganji R, Grabowski A, Buhl M, Zikmund T, Kavkova M, Axelson H, Lindgren D, Kramann R, Kuppe C, Erdélyi F, Máté Z, Szabó G, Koehne T, Harkany T, Fried K, Kaiser J, Boor P, Fekete C, Rozman J, Kasparek P, Prochazka J, Sedlacek R, Bryja V, Gusev O, Adameyko I (2023) A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology Nat Commun, 14 (1): 3092
2023 Reviews
- Harkany T, Hökfelt T (2023) Neuroglia: Function and Pathology by Alexei Verkhratsky and Arthur M. Butt Acta Physiol (Oxf)., 239 (2)
2022 Original Articles
- Steffens S, Bakker J, Glat M, Keimpema E, Pollak D, Hökfelt T, Harkany T (2022) 3D‐printed design of a stereotaxic adaptor for the precision targeting of brain structures in infant mice Eur J Neurosci, 55 (3): 725-732
- Krassnitzer M, Boisvert B, Beiersdorf J, Harkany T, Keimpema E (2022) Resident Astrocytes can Limit Injury to Developing Hippocampal Neurons upon THC Exposure Neurochem Res, 48 (4): 1242-1253
- Korchynska S, Rebernik P, Pende M, Boi L, Alpár A, Tasan R, Becker K, Balueva K, Saghafi S, Wulff P, Horvath T, Fisone G, Dodt H, Hökfelt T, Harkany T, Romanov R (2022) A hypothalamic dopamine locus for psychostimulant-induced hyperlocomotion in mice Nat Commun, 13 (1)
- Fallatah W, Cui W, Di Pietro E, Carter G, Pounder B, Dorninger F, Pifl C, Moser A, Berger J, Braverman N (2022) A Pex7 Deficient Mouse Series Correlates Biochemical and Neurobehavioral Markers to Genotype Severity—Implications for the Disease Spectrum of Rhizomelic Chondrodysplasia Punctata Type 1 Front Cell Dev Biol, 10
| Article (PDF) | - Zambon A, Rico L, Herman M, Gundacker A, Telalovic A, Hartenberger L, Kuehn R, Romanov R, Hussaini S, Harkany T, Pollak D (2022) Gestational immune activation disrupts hypothalamic neurocircuits of maternal care behavior Mol Psychiatry,
2021 Original Articles
- Tortoriello G, Beiersdorf J, Romani S, Williams G, Cameron G, Mackie K, Williams M, Di Marzo V, Keimpema E, Doherty P, Harkany T (2021) Genetic Manipulation of sn-1-Diacylglycerol Lipase and CB1 Cannabinoid Receptor Gain-of-Function Uncover Neuronal 2-Linoleoyl Glycerol Signaling in Drosophila melanogaster Cannabis Cannabinoid Res, 6 (2): 119-136
- da Silva SR, Kalaba P, Fabisikova A, Zehl M, Dragacevic V, Ribeiro dos Anjos L, Neill PJ, Wieder M, Prado-Roller A, Gajic N, Palaretti V, da Silva GVJ, Pifl C, Lubec G, Gonzalez ERP (2021) Synthesis and dopamine receptor binding of dihydrexidine and SKF 38393 catecholamine-based analogues Amino Acids, Published Online: 29 November 2021
- Lubec J, Kalaba P, Hussein A, Feyissa D, Kotob M, Mahmmoud R, Wieder O, Garon A, Sagheddu C, Ilic M, Dragačević V, Cybulska-Klosowicz A, Zehl M, Wackerlig J, Sartori S, Ebner K, Kouhnavardi S, Roller A, Gajic N, Pistis M, Singewald N, Leban J, Korz V, Malikovic J, Plasenzotti R, Sitte H, Monje F, Langer T, Urban E, Pifl C, Lubec G (2021) Reinstatement of synaptic plasticity in the aging brain through specific dopamine transporter inhibition Mol Psychiatry,
- Bhat S, Niello M, Schicker K, Pifl C, Sitte H, Freissmuth M, Sandtner W (2021) Handling of intracellular K+ determines voltage dependence of plasmalemmal monoamine transporter function eLife, 10
- Patthy �, Murai J, Hanics J, Pintér A, Zahola P, Hökfelt T, Harkany T, Alpár A (2021) Neuropathology of the Brainstem to Mechanistically Understand and to Treat Alzheimer’s Disease J Clin Med, 10 (8): 1555
2021 Reviews
- Keimpema E, Di Marzo V, Harkany T (2021) Biological basis of cannabinoid medicines Science, 374 (6574): 1449-1450
- Zecca L, Pifl C, Fahn S, Sulzer D, Fariello R (2021) Oleh Hornykiewicz, a giant in the understanding and treatment of Parkinson disease npj Parkinson's Disease, 7 (1)
2020 Original Articles
- Beiersdorf J, Hevesi Z, Calvigioni D, Pyszkowski J, Romanov RA, Szodorai E, Lubec G, Shirran S, Botting CH, Kasper S, Guy GW, Gray R, Di Marzo V, Harkany T, Keimpema E (2020) Adverse effects of tetrahydrocannabinol on neuronal bioenergetics during postnatal brain development. JCI Insight, 5: e135418
| Weblink | - Orthofer M, Valsesia A, Mägi R, Wang Q, Kaczanowska J, Kozieradzki I, Leopoldi A, Cikes D, Zopf L, Tretiakov E, Demetz E, Hilbe R, Boehm A, Ticevic M, Nõukas M, Jais A, Spirk K, Clark T, Amann S, Lepamets M, Neumayr C, Arnold C, Dou Z, Kuhn V, Novatchkova M, Cronin S, Tietge U, Müller S, Pospisilik J, Nagy V, Hui C, Lazovic J, Esterbauer H, Hagelkruys A, Tancevski I, Kiefer F, Harkany T, Haubensak W, Neely G, Metspalu A, Hager J, Gheldof N, Penninger J (2020) Identification of ALK in Thinness Cell, 181 (6): 1246-1262.e22
| Weblink | - Cinquina V, Calvigioni D, Farlik M, Halbritter F, Gernedl V, Shirran SL, Fuszard MA, Botting CH, Poullet P, Piscitelli F, Máté Z, Szabó G, Yanagawa Y, Kasper S, Di Marzo V, Mackie K, McBain CJ, Bock C, Keimpema E, Harkany T (2020) Life-long epigenetic programming of cortical architecture by maternal ‘Western’ diet during pregnancy Mol Psychiatry, 25 (1): 22-36
| Weblink | - Krivanek J, Soldatov R, Kastriti M, Chontorotzea T, Herdina A, Petersen J, Szarowska B, Landova M, Matejova V, Holla L, Kuchler U, Zdrilic I, Vijaykumar A, Balic A, Marangoni P, Klein O, Neves V, Yianni V, Sharpe P, Harkany T, Metscher B, Bajénoff M, Mina M, Fried K, Kharchenko P, Adameyko I (2020) Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth Nat Commun, 11 (1): 4816
- Pifl C, Sitte H (2020) A Tribute to Oleh Hornykiewicz (1926–2020) Trends Pharmacol Sci, 41 (8): 499-501
- Romanov R, Tretiakov E, Kastriti M, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews W, Parnavelas J, Farlik M, Bock C, Adameyko I, Hökfelt T, Keimpema E, Harkany T (2020) Molecular design of hypothalamus development Nature, 582(7811): 246-252
2020 Reviews
- Keimpema E, Harkany T, Alpár A (2020) The p(l)ot thickens: cannabinoid receptors on astroglial mitochondria coordinate animal behaviors by regulating lactate availability for neurons Signal Transduct Target Ther, 5 (1)
2019 Original Articles
- Daba Feyissa D, Sialana F, Keimpema E, Kalaba P, Paunkov A, Engidawork E, Höger H, Lubec G, Korz V (2019) Dopamine type 1- and 2-like signaling in the modulation of spatial reference learning and memory Behav Brain Res, 362: 173-180
- Kalaba P, Ilić M, Aher N, Dragačević V, Wieder M, Zehl M, Wackerlig J, Beyl S, Sartori S, Ebner K, Roller A, Lukic N, Beryozkina T, Gonzalez E, Neill P, Khan J, Bakulev V, Leban J, Hering S, Pifl C, Singewald N, Lubec J, Urban E, Sitte H, Langer T, Lubec G (2019) Structure–Activity Relationships of Novel Thiazole-Based Modafinil Analogues Acting at Monoamine Transporters J Med Chem, 63 (1): 391-417
- Hörtnagl H, Pifl C, Hörtnagl E, Reiner A, Sperk G (2019) Distinct gradients of various neurotransmitter markers in caudate nucleus and putamen of the human brain J Neurochem, 152 (6): 650-662
- Korchynska S, Krassnitzer M, Malenczyk K, Prasad R, Tretiakov E, Rehman S, Cinquina V, Gernedl V, Farlik M, Petersen J, Hannes S, Schachenhofer J, Reisinger S, Zambon A, Asplund O, Artner I, Keimpema E, Lubec G, Mulder J, Bock C, Pollak D, Romanov R, Pifl C, Groop L, Hökfelt T, Harkany T (2019) Life‐long impairment of glucose homeostasis upon prenatal exposure to psychostimulants EMBO J., 39 (1)
2019 Reviews
- Pifl C (2019) The Time Delay Between In Vivo Imaging and Postmortem Data Poses a Caveat on “No Link” Findings Movement Disorders, 34: 1579-1580
2018 Original Articles
- Alpár A, Zahola P, Hanics J, Hevesi Z, Korchynska S, Benevento M, Pifl C, Zachar G, Perugini J, Severi I, Leitgeb P, Bakker J, Miklosi AG, Tretiakov E, Keimpema E, Arque G, Tasan RO, Sperk G, Malenczyk K, Máté Z, Erdélyi F, Szabó G, Lubec G, Palkovits M, Giordano A, Hökfelt TG, Romanov RA, Horvath TL, Harkany T. (2018) Hypothalamic CNTF volume transmission shapes cortical noradrenergic excitability upon acute stress EMBO J., 37: e100087
- Maier J, Mayer FP, Luethi D, Holy M, Jaentsch K, Reither H, Hirtler L, Hoener MC, Liechti ME, Pifl C, Brandt SD, Sitte HH (2018) The psychostimulant (±)-cis-4,4′-dimethylaminorex (4,4′-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters Neuropharmacology, 138: 282-291
2017 Original Articles
- Milenkovic I, Stojanovic T, Aronica E, Fülöp L, Bozsó Z, Máté Z, Yanagawa Y, Adle-Biassette H, Lubec G, Szabó G, Harkany T, Kovács G, Keimpema E (2017) GABAA receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome Brain Struct Funct,
- Romanov R, Zeisel A, Bakker J, Girach F, Hellysaz A, Tomer R, Alpár A, Mulder J, Clotman F, Keimpema E, Hsueh B, Crow A, Martens H, Schwindling C, Calvigioni D, Bains J, Máté Z, Szabó G, Yanagawa Y, Zhang M, Rendeiro A, Farlik M, Uhlén M, Wulff P, Bock C, Broberger C, Deisseroth K, Hökfelt T, Linnarsson S, Horvath T, Harkany T (2017) Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes Nature Neurosci, 20 (2): 176-188
- Hornykiewicz O (2017) L-DOPA J Parkinson Dis, 7 (s1): S3-S10
- Tong J, Rathitharan G, Meyer JH, Furukawa Y, Ang LC, Boileau I, Guttman M, Hornykiewicz O, Kish SJ (2017) Brain monoamine oxidase B and A in human parkinsonian dopamine deficiency disorders Brain, 140: 2460-2474
- Ghafari M, Falsafi S, Szodorai E, Kim E, Li L, Höger H, Berger J, Fuchs K, Sieghart W, Lubec G (2017) Formation of GABAA receptor complexes containing α1 and α5 subunits is paralleling a multiple T-maze learning task in mice Brain Struct Funct, 222 (1): 549-561
- Pifl C, Reither H, Lopez-Gonzalez del Rey N, Cavada C, Obeso JA, Blesa J (2017) Early paradoxical increase of dopamine: A neurochemical study of olfactory bulb in asymptomatic and symptomatic MPTP treated monkeys Front Neuroanat, 11: 46
- Rivetti di Val Cervo P, Romanov RA, Spigolon G, Masini D, Martín-Montañez E, Toledo EM, La Manno G, Feyder M, Pifl C, Ng YH, Sánchez SP, Linnarsson S, Wernig M, Harkany T, Fisone G, Arenas E (2017) Induction of functional dopamine neurons from human astrocytes in vitro and mouse astrocytes in a Parkinson's disease model Nat Biotechnol, 35: 444-452
- Hanics J, Szodorai E, Tortoriello G, Malenczyk K, Keimpema E, Lubec G, Hevesi Z, Lutz M, Kozsurek M, Puskár Z, Tóth Z, Wagner L, Kovács G, Hökfelt T, Harkany T, Alpár A (2017) Secretagogin-dependent matrix metalloprotease-2 release from neurons regulates neuroblast migration PNAS, 114 (10): E2006-E2015
2016 Original Articles
- Calvigioni D, Máté Z, Fuzik J, Girach F, Zhang M, Varro A, Beiersdorf J, Schwindling C, Yanagawa Y, Dockray G, McBain C, Hökfelt T, Szabó G, Keimpema E, Harkany T (2016) Functional Differentiation of Cholecystokinin-Containing Interneurons Destined for the Cerebral Cortex Cereb. Cortex, : bhw094
- Hoerbelt P, Ramerstorfer J, Ernst M, Sieghart W, Thomson JL, Hough LB, Fleck MW (2016) Mutagenesis and computational docking studies support the existence of a histamine binding site at the extracellular b3+b3- interface of homooligomeric b3 GABA-A receptors Neuropharmacology, 108: 252-263
- Jonas O, Calligaris D, Methuku K, Poe M, Francois J, Tranghese F, Changelian A, Sieghart W, Ernst M, Pomeranz Krummel D, Cook J, Pomeroy S, Cima M, Agar N, Langer R, Sengupta S (2016) First In Vivo Testing of Compounds Targeting Group 3 Medulloblastomas Using an Implantable Microdevice as a New Paradigm for Drug Development J Biomed Nanotech, 12 (6): 1297-1302
- Pifl C (2016) Problems with traffic ahead: Synaptic vesicles in Parkinson's disease Movement Disorders, 31: 1480
- Sitte HH, Pifl C, Rajput AH, Hörtnagl H, Tong J, Lloyd GK, Kish SJ, Hornykiewicz O (2016) Dopamine and noradrenaline, but not serotonin, in the human claustrum are greatly reduced in patients with Parkinson's disease: possible functional implications Eur J Neurosci, 45: 192-197
- Furukawa Y, Rajput A, Tong J, Tomizawa Y, Hornykiewicz O, Kish S (2016) A marked contrast between serotonergic and dopaminergic changes in dopa-responsive dystonia: Table Neurology, 87 (10): 1060-1061
- Marques S, Zeisel A, Codeluppi S, van Bruggen D, Mendanha Falcao A, Xiao L, Li H, Haring M, Hochgerner H, Romanov R, Gyllborg D, Munoz-Manchado A, La Manno G, Lonnerberg P, Floriddia E, Rezayee F, Ernfors P, Arenas E, Hjerling-Leffler J, Harkany T, Richardson W, Linnarsson S, Castelo-Branco G (2016) Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system Science, 352 (6291): 1326-1329
| Article (PDF) || Weblink | - Peneder T, Bauer J, Pifl C (2016) Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice Movement Disorders, 31: 1729-1733
- Zhang MD, Barde S, Szodorai E, Josephson A, Mitsios N, Watanabe M, Attems J, Lubec G, Kovacs GM, Uhlen M, Mulder J, Harkany T, Hökfelt T (2016) Comparative anatomical distribution of neuronal calcium-binding protein (NECAB) 1 and -2 in rodent and human spinal cord Brain Struct Funct, 221 (7): 3803-3823
| Article (PDF) || Weblink | - Berger ML (2016) Soaping the NMDA receptor: Various types of detergents influence differently [³H]MK-801 binding to rat brain membranes Biochim Biophys Acta, 1858: 116-122
2016 Reviews
- Adameyko I, Fried K (2016) The Nervous System Orchestrates and Integrates Craniofacial Development: A Review Front Physiol, 7
| Article (PDF) || Weblink |
2015 Original Articles
- Pangratz-Fuehrer S, Sieghart W, Rudolph U, Parada I, Huguenard J (2015) Early postnatal switch in GABAAreceptor α-subunits in the reticular thalamic nucleus J. Neurophysiol., 115 (3): 1183-1195
- Ernst M, Sieghart W (2015) GABAA – Rezeptorsubtypen: Strukturelle Vielfalt gibt Hoffnung auf neue Therapiekonzepte Neuroforum, 21 (4): 144-151
- Ernst M, Sieghart W (2015) GABAA receptor subtypes: structural variety raises hope for new therapy concepts e-Neuroforum, 6 (4): 97-103
- Kudryavtsev D, Shelukhina I, Son L, Ojomoko L, Kryukova E, Lyukmanova E, Zhmak M, Dolgikh D, Ivanov I, Kasheverov I, Starkov V, Ramerstorfer J, Sieghart W, Tsetlin V, Utkin Y (2015) Neurotoxins from Snake Venoms and α-Conotoxin ImI Inhibit Functionally Active Ionotropic γ-Aminobutyric Acid (GABA) Receptors J Biol Chem, 290 (37): 22747-22758
- Sieghart W (2015) Allosteric Modulation of GABAA Receptors via Multiple Drug-Binding Sites Adv Pharmacol, : 53-96
- Rycek L, Puthenkalam R, Schnürch M, Ernst M, Mihovilovic M (2015) Metal-assisted synthesis of unsymmetrical magnolol and honokiol analogs and their biological assessment as GABAA receptor ligands Bioorg Med Chem Lett, 25 (2): 400-403
- Yocum GT, Gallos G, Zhang Y, Jahan R, Stephen MR, Varagic Z, Puthenkalam R, Ernst M, Cook JM, Emala CW (2015) Targeting the GABAA Receptor α4 Subunit in Airway Smooth Muscle to Alleviate Bronchoconstriction Am J Respir Cell Mol Biol, Sept 25: Epub ahead of print
- Ádori C, Glück L, Barde S, Yoshitake T, Kovacs G, Mulder J, Maglóczky Z, Havas L, Bölcskei K, Mitsios N, Uhlén M, Szolcsányi J, Kehr J, Rönnbäck A, Schwartz T, Rehfeld J, Harkany T, Palkovits M, Schulz S, Hökfelt T (2015) Critical role of somatostatin receptor 2 in the vulnerability of the central noradrenergic system: new aspects on Alzheimer’s disease Acta Neuropathol, 129 (4): 541-563
- Guggenhuber S, Alpar A, Chen R, Schmitz N, Wickert M, Mattheus T, Harasta AE, Purrio M, Kaiser N, Elphick MR, Monory K, Kilb W, Luhmann HJ, Harkany T, Lutz B, Klugmann M (2015) Cannabinoid receptor-interacting protein Crip 1a modulates CB1 receptor signaling in mouse hippocampus Brain Struct Funct, March 15: Epub ahead of print
- Penz O, Fuzik J, Kurek A, Romanov R, Larson J, Park T, Harkany T, Keimpema E (2015) Protracted brain development in a rodent model of extreme longevity Sci Rep, 5: 11592
| Article (PDF): 1 2 | - Valladolid-Acebes I, Daraio T, Brismar K, Harkany T, Ögren S, Hökfelt T, Bark C (2015) Replacing SNAP-25b with SNAP-25a expression results in metabolic disease PNAS, 112 (31): E4326-E4335
- Bitencourt R, Alpár A, Cinquina V, Ferreira S, Pinheiro B, Lemos C, Ledent C, Takahashi R, Sialana F, Lubec G, Cunha R, Harkany T, Köfalvi A (2015) Lack of presynaptic interaction between glucocorticoid and CB1 cannabinoid receptors in GABA- and glutamatergic terminals in the frontal cortex of laboratory rodents Neurochem Internat, 90: 72-84
- Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Björklund P, Mackie K, Di Marzo V, Hökfelt T, Dobrzyn A, Harkany T (2015) Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture PNAS, 112 (45): E6185-E6194
- Alpár A, Di Marzo V, Harkany T (2015) At the Tip of an Iceberg: Prenatal Marijuana and Its Possible Relation to Neuropsychiatric Outcome in the Offspring Biol Psychiatry,
- Tesoriero C, Codita A, Zhang M, Cherninsky A, Karlsson H, Grassi-Zucconi G, Bertini G, Harkany T, Ljungberg K, Liljeström P, Hökfelt T, Bentivoglio M, Kristensson K (2015) H1N1 influenza virus induces narcolepsy-like sleep disruption and targets sleep–wake regulatory neurons in mice PNAS, 113 (3): E368-E377
- Fuzik J, Zeisel A, Máté Z, Calvigioni D, Yanagawa Y, Szabó G, Linnarsson S, Harkany T (2015) Integration of electrophysiological recordings with single-cell RNA-seq data identifies neuronal subtypes Nat Biotechnol, 34 (2): 175-183
- Ivashkin E, Khabarova M, Melnikova V, Nezlin LP, Kharchenko O, Voronezhskaya EE, Adameyko I (2015) Serotonin Mediates Maternal Effects and Directs Developmental and Behavioral Changes in the Progeny of Snails Cell Rep, 12 (7): 1144-1158
| Article (PDF) || Weblink | - Hnat J, Berger ML (2015) Radioligand kinetics at the NMDA receptor channel revisited: an active part by Na+ and Tris Neurotransmitter, 2: e 945
- Hornykiewicz O (2015) 50 years of levodopa Movement Disorders, 30: 1008
- Tong J, Ang LC, Williams B, Furukawa Y, Fitzmaurice P, Guttman M, Boileau I, Hornykiewicz O, Kish SJ (2015) Low levels of astroglial markers in Parkinson's disease: relationship to alpha-synuclein accumulation Neurobiol Dis, 82: 243-253
- Berger ML, Rebernik P (2015) Differential influence of 7 cations on 16 non-competitive NMDA receptor blockers Bioorg Med Chem Lett, 25 (19): 4131-4135
| Article (PDF) || Weblink | - Karabacak Y, Sase S, Aher YD, Sase A, Saroja SR, Cicvaric A, Höger H, Berger M, Bakulev V, Sitte HH, Leban J, Monje FJ, Lubec G (2015) The effect of modafinil on the rat dopamine transporter and dopamine receptors D1-D3 paralleling cognitive enhancement in the radial arm maze Front Behav Neurosci, Epub August 2015
- Ramerstorfer J, Foppa V, Thiery H, Hermange P, Janody S, Berger M, Dodd R, Sieghart W (2015) GABAA Receptor Subtype-Selectivity of Novel Bicuculline Derivates Curr Med Chem, 22: 771-780
- Berger M, Maciejewska D, Vanden Eynde JJ, Mottamal M, Zabinski J, Kazmierczak P, Rezler M, Jarak I, Piantanida I, Karminski-Zamola G, Mayence A, Rebernik P, Kumar A, Ismail MA, Boykin DW, Huang TL (2015) Pentamidine analogs as iInhibitors of [3H]MK-801 and [3H]ifenprodil binding to rat brain NMDA receptors Bioorg Med Chem, 23 (15): 4489-4500
| Article (PDF): 1 2 || Weblink |
2014 Original Articles
- Keimpema E, Zheng K, Barde SS, Berghuis P, Dobszay MB, Schnell R, Mulder J, Luiten PG, Xu ZD, Runesson J, Langel Ü, Lu B, Hökfelt T, Harkany T (2014) GABAergic terminals are a source of galanin to modulate cholinergic neuron development in the neonatal forebrain Cereb. Cortex,
- Alpár A, Tortoriello G, Calvigioni D, Niphakis M, Milenkovic I, Bakker J, Cameron G, Hanics J, Morris C, Fuzik J, Kovacs G, Cravatt B, Parnavelas J, Andrews W, Hurd Y, Keimpema E, Harkany T (2014) Endocannabinoids modulate cortical development by configuring Slit2/Robo1 signalling Nat Commun, 5
- Obradović A, Joksimović S, Poe M, Ramerstorfer J, Varagic Z, Namjoshi O, Batinić B, Radulović T, Marković B, Roth B, Sieghart W, Cook J, Savić M (2014) Sh-I-048A, an in vitro non-selective super-agonist at the benzodiazepine site of GABAA receptors: The approximated activation of receptor subtypes may explain behavioral effects Brain Res, 1554: 36-48
- Middendorp S, Puthenkalam R, Baur R, Ernst M, Sigel E (2014) Accelerated Discovery of Novel Benzodiazepine Ligands by Experiment-Guided Virtual Screening ACS Chem Biol, 9 (8): 1854-1859
- Carta V, Pangerl M, Baur R, Puthenkalam R, Ernst M, Trauner D, Sigel E (2014) A Pentasymmetric Open Channel Blocker for Cys-Loop Receptor Channels PLoS One, 9 (9): e106688
- Iannotti F, Silvestri C, Mazzarella E, Martella A, Calvigioni D, Piscitelli F, Ambrosino P, Petrosino S, Czifra G, Biro T, Harkany T, Taglialatela M, Di Marzo V (2014) The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels PNAS, 111 (24): E2472-E2481
- Parnia S, Spearpoint K, de Vos G, Fenwick P, Goldberg D, Yang J, Zhu J, Baker K, Killingback H, Beisteiner R, Berger M, Bullock S, Sutton J, Walmsley A, Deakin CD, Little P, Farber M, Greyson B, Schoenfeld ER (2014) AWARE-AWAREness during REsuscitation-A prospective study Resuscitation, 85: 1799-1805
- Romanov R, Alpar A, Zhang M, Zeisel A, Calas A, Landry M, Fuszard M, Shirran SL, Schnell R, Dobolyi A, Olah M, Spence L, Mulder J, Martens H, Palkovits M, Uhlen M, Sitte H, Botting CH, Wagner L, Linnarsson S, Hökfelt T, Harkany T (2014) A secretagonin locus of the mammalian hypothalamus controls stress hormon release EMBO J., 34 (1): 36-54
| Article (PDF) | - Maccarrone M, Guzman M, Mackie K, Doherty P, Harkany T (2014) Programming of neural cells by (endo)cannabinoids: from physiological rules to emerging therapies Nat. Rev. Neurosci., 15: 786-801
- Ferreira SG, Goncalves FQ, Marques JM, Tomé AR, Rodrigues RJ, Nunes-Correia I, Ledent C, Harkany T, Venance L, Cunha RA, Köfalvi A (2014) Presynaptic A2A adenosine receptors dampen CB1 cannabinoid receptor-mediated inhibition of corticostriatal glutamatergic transmission Br J Pharmacol, Oct 9
- Harkany T, Zeilhofer HU, Cattaneo A (2014) Neurotrophin and endocannabinoid interactions in the neurobiology of pain Eur J Neurosci, 39: 331-333
- Gati G, Lendvai D, Hökfelt T, Harkany T, Alpar A (2014) Revival of calcium-binding proteins for neuromorphology: secretagonin typifies distinct cell populations in the avian brain Brain Behav Evol, Epub April 24. 2014
- Iannotti FA, Silvestri C, Mazzarella E, Martella A, Calvigioni D, Piscitelli F, Ambrosino P, Petrosino S, Czifra G, Biro T, Harkany T, Taglialatela M, Di Marzo V (2014) The endocannabinoid 2-AG controls skeletal muscle cell differentiation via CB1 receptor-dependent inhibition of Kv7 channels Proc Natl Acad Sci USA, Epub June 3, 2014
- Tortoriello G, Morris CV, Alpar A, Fuzik J, Shirran SL, Calvigioni D, Keimpema E, Botting CH, Reinecke K, Herdegen T, Courtney M, Hurd YL, Harkany T (2014) Miswiring the brain: delta9-tetrahydrocannabinol disrupts cortical development by inducing an SCG10/stathmin-2 degradation pathway Embo Journ, 33: 668-85
2014 Reviews
- Keimpema E, Hökfelt T, Harkany T, Doherty P (2014) The molecular interplay between endocannabinoid and neurotrophin signals in the nervous system and beyond Eur J Neurosci, 39: 334-343
- Calvigioni D, Hurd YL, Harkany T, Keimpema E, (2014) Neuronal substrates and functional consequences of prenatal cannabis exposure Child Adolesc Psychiatry Ment Health, Epub May 3, 2014
2014 Book Chapters
- Sieghart W (2014) GABA-A receptors in the brain: exciting targets for the development of clinically important drugs. In: , Magyar Tudomanyos Akademia k.A.: k.A.
2013 Original Articles
- Keimpema E, Alpár A, Howell F, Malenczyk K, Hobbs C, Hurd Y, Watanabe M, Sakimura K, Kano M, Doherty P, Harkany T (2013) Diacylglycerol lipase α manipulation reveals developmental roles for intercellular endocannabinoid signaling Sci Rep, 3 (1)
- Baur R, Kielar M, Richter L, Ernst M, Ecker G, Sigel E (2013) Molecular analysis of the site for 2-arachidonylglycerol (2-AG) on the β 2 subunit of GABA A receptors J Neurochem, 126 (1): 29-36
- Palangsuntikul R, Berner H, Berger ML,Wolschann P (2013) Holographic Quantitative Structure-Activity Relationships of Tryptamine Derivatives at NMDA, 5HT-1A and 5HT-2A Receptors Molecules, 18: 8799-8811
- Keimpema E, Tortoriello G, Alpar A, Capsoni S, Arisi I, Calvigioni D, Hu S, Cattaneo A, Doherty P, Mackie K, Harkany T (2013) Nerve growth factor scales endocannabinoid signaling by regulating monoacylglycerol lipase turnover in developing cholinergic neurons PNAS, 110: 1935-1940
- Malenczyk K, Jazurek M, Keimpema E, Silvestri C, Janikiewicz J, Mackie K, Di Marzo V, Redowicz MJ, Harkany T, Dobrzyn A (2013) CB1 Cannabinoid Receptors Couple to Focal Adhesion Kinase to Control Insulin Release J Biol Chem, 288: 32685-32699
2013 Reviews
- Keimpema E, Calvigioni D, Harkany T (2013) Endocannabinoid signals in the developmental programming of delayed-onset neuropsychiatric and metabolic illnesses Biochem. Soc. Trans., 41: 1569-1576
2012 Reviews
- Keimpema E, Straiker A, Mackie K, Harkany T, Hjerling‐Leffler J (2012) Sticking out of the crowd: the molecular identity and development of cholecystokinin‐containing basket cells Am J Physiol, 590 (4): 703-714
2011 Original Articles
- Mulder J, Zilberter M, Pasquaré S, Alpár A, Schulte G, Ferreira S, Köfalvi A, Martín-Moreno A, Keimpema E, Tanila H, Watanabe M, Mackie K, Hortobágyi T, de Ceballos M, Harkany T (2011) Molecular reorganization of endocannabinoid signalling in Alzheimer’s disease Brain, 134 (4): 1041-1060
2011 Reviews
- Keimpema E, Mackie K, Harkany T (2011) Molecular model of cannabis sensitivity in developing neuronal circuits Trends Pharmacol Sci, 32 (9): 551-561
2010 Original Articles
- Keimpema E, Barabas K, Morozov Y, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T (2010) Differential Subcellular Recruitment of Monoacylglycerol Lipase Generates Spatial Specificity of 2-Arachidonoyl Glycerol Signaling during Axonal Pathfinding J Neurosci, 30 (42): 13992-14007
2008 Original Articles
- Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado C, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd Y, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu H, Galve-Roperh I, Harkany T (2008) Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning Proc Natl Acad Sci USA, 105 (25): 8760-8765
2008 Reviews
- Harkany T, Keimpema E, Barabás K, Mulder J (2008) Endocannabinoid functions controlling neuronal specification during brain development Mol Cell Endocrinol, 286 (1-2): S84-S90
