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2024 Original Articles

  • Lewis E, Al Khazal F, Wilbanks B, Gades N, Ortega‐Sáenz P, López‐Barneo J, Adameyko I, Maher L (2024) Mouse developmental defects, but not paraganglioma tumorigenesis, upon conditional Complex II loss in early Sox10<sup>+</sup> cells FASEB Bioadv, 6 (9): 327-336
  • Boutou A, Roufagalas I, Politopoulou K, Tastsoglou S, Abouzeid M, Skoufos G, Verdu de Juan L, Ko J, Kyrargyri V, Hatzigeorgiou A, Barnum C, Tesi R, Bauer J, Lassmann H, Johnson M, Probert L (2024) Microglia regulate cortical remyelination via TNFR1-dependent phenotypic polarization Cell Rep, 43 (11): 114894
  • Winklehner M, Wickel J, Gelpi E, Brämer D, Rauschenberger V, Günther A, Bauer J, Serra A, Jauk P, Villmann C, Höftberger R, Geis C (2024) Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor and GAD65 Antibodies Neurol Neuroimmunol Neuroinflamm, 11 (6): e200298
  • Bien C, Rada A, Mertens M, Bien C, Bauer J, Hagemann A, Woermann F (2024) LGI1 encephalitis: potentially complement-activating anti-LGI1-IgG subclasses 1/2/3 are associated with the development of hippocampal sclerosis J Neurol, 271 (9): 6325-6335
  • Roll W, Bauer J, Dik A, Mueller C, Backhaus P, Räuber S, Zinnhardt B, Gallus M, Wimberley C, Körtvelyessy P, Schindler P, Stenzel W, Elger C, Becker A, Lewerenz J, Wiendl H, Meuth S, Schäfers M, Melzer N (2024) 18F-DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis J Neurol, 271 (6): 3653-3659
  • Beliën J, Swinnen S, D’hondt R, de Juan L, Dedoncker N, Matthys P, Bauer J, Vens C, Moylett S, Dubois B (2024) CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis Nat Commun, 15 (1): 5013
  • Yu W, Kastriti M, Ishan M, Choudhary S, Rashid M, Kramer N, Do H, Wang Z, Xu T, Schwabe R, Ye K, Adameyko I, Liu H (2024) The duct of von Ebner’s glands is a source of Sox10+ taste bud progenitors and susceptible to pathogen infections Front Cell Dev Biol, 12: 12:1460669
  • Olsen T, Otte J, Mei S, Embaie B, Kameneva P, Cheng H, Gao T, Zachariadis V, Tsea I, Björklund ?, Kryukov E, Hou Z, Johansson A, Sundström E, Martinsson T, Fransson S, Stenman J, Fard S, Johnsen J, Kogner P, Adameyko I, Enge M, Kharchenko P, Baryawno N (2024) Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastoma Mol Cancer, 23 (1): 180
  • Erickson A, Motta A, Kastriti M, Edwards S, Coulpier F, Théoulle E, Murtazina A, Poverennaya I, Wies D, Ganofsky J, Canu G, Lallemend F, Topilko P, Hadjab S, Fried K, Ruhrberg C, Schwarz Q, Castellani V, Bonanomi D, Adameyko I (2024) Motor innervation directs the correct development of the mouse sympathetic nervous system Nat Commun, 15 (1): 7065
  • Kaneko K, Kuroda H, Matsumoto Y, Sakamoto N, Yamazaki N, Yamamoto N, Umezawa S, Namatame C, Ono H, Takai Y, Takahashi T, Fujimori J, Nakashima I, Harigaya Y, Lassmann H, Fujihara K, Misu T, Aoki M (2024) Different Complement Activation Patterns Following C5 Cleavage in MOGAD and AQP4-IgG+NMOSD Neurol Neuroimmunol Neuroinfl, 11 (5): e200293
  • Kibalnyk Y, Afanasiev E, Noble R, Watson A, Poverennaya I, Dittmann N, Alexiou M, Goodkey K, Greenwell A, Ussher J, Adameyko I, Massey J, Graf D, Bourque S, Stratton J, Voronova A (2024) The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function Nat Commun, 15 (1): 4632
  • Jevans B, Cooper F, Fatieieva Y, Gogolou A, Kang Y, Restuadi R, Moulding D, Vanden Berghe P, Adameyko I, Thapar N, Andrews P, De Coppi P, Tsakiridis A, McCann C (2024) Human enteric nervous system progenitor transplantation improves functional responses in Hirschsprung disease patient-derived tissue Gut, 73(9): 1441-1453
  • Xie M, Kaiser M, Gershtein Y, Schnyder D, Deviatiiarov R, Gazizova G, Shagimardanova E, Zikmund T, Kerckhofs G, Ivashkin E, Batkovskyte D, Newton P, Andersson O, Fried K, Gusev O, Zeberg H, Kaiser J, Adameyko I, Chagin A (2024) The level of protein in the maternal murine diet modulates the facial appearance of the offspring via mTORC1 signaling Nat Commun, 15 (1): 2367
  • Guo Y, Endmayr V, Zekeridou A, McKeon A, Leypoldt F, Hess K, Kalinowska-Lyszczarz A, Klang A, Pakozdy A, Höftberger E, Hametner S, Haider C, De Simoni D, Peters S, Gelpi E, Röcken C, Oberndorfer S, Lassmann H, Lucchinetti C, Höftberger R (2024) New insights into neuropathology and pathogenesis of autoimmune glial fibrillary acidic protein meningoencephalomyelitis Acta Neuropathol, 147 (1): 31
  • Avloniti M, Evangelidou M, Gomini M, Loupis T, Emmanouil M, Mitropoulou A, Tselios T, Lassmann H, Gruart A, Delgado-García J, Probert L, Kyrargyri V (2024) IKKβ deletion from CNS macrophages increases neuronal excitability and accelerates the onset of EAE, while from peripheral macrophages reduces disease severity J Neuroinflammation, 21 (1): 34
  • Steinmaurer A, Riedl C, König T, Testa G, Köck U, Bauer J, Lassmann H, Höftberger R, Berger T, Wimmer I, Hametner S (2024) The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis Brain Pathol, 34(5): e13240

2024 Reviews

  • Geraldes R, Arrambide G, Banwell B, Rovira A, Cortese R, Lassmann H, Messina S, Rocca M, Waters P, Chard D, Gasperini C, Hacohen Y, Mariano R, Paul F, DeLuca G, Enzinger C, Kappos L, Leite M, Sastre-Garriga J, Yousry T, Ciccarelli O, Filippi M, Barkhof F, Palace J, (2024) The influence of MOGAD on diagnosis of multiple sclerosis using MRI Nat Rev Neurol, 20(10): 620-635
  • Kaiser M, Zikmund T, Vora S, Metscher B, Adameyko I, Richman J, Kaiser J (2024) 3D atlas of the human fetal chondrocranium in the middle trimester Sci Data, 11 (1): 626
  • Filippi M, Preziosa P, Barkhof F, Ciccarelli O, Cossarizza A, De Stefano N, Gasperini C, Geraldes R, Granziera C, Haider L, Lassmann H, Margoni M, Pontillo G, Ropele S, Rovira ?, Sastre-Garriga J, Yousry T, Rocca M, Rocca M, Sastre-Garriga J, Barkhof F, Ciccarelli O, de Stefano N, Filippi M, Gasperini C, Kappos L, De Luca G, Enzinger C, Rovira ?, Schoonheim M, Yousry T, (2024) The ageing central nervous system in multiple sclerosis: the imaging perspective Brain, 47(11): 3665-3680
  • Schmierer K, Lassmann H (2024) The shoulders we keep standing on: remembering Otto Marburg, a big brain in neurology and multiple sclerosis, at 150 Acta Neuropathol, 147 (1): 81
  • Calabrese M, Preziosa P, Scalfari A, Colato E, Marastoni D, Absinta M, Battaglini M, De Stefano N, Di Filippo M, Hametner S, Howell O, Inglese M, Lassmann H, Martin R, Nicholas R, Reynolds R, Rocca M, Tamanti A, Vercellino M, Villar L, Filippi M, Magliozzi R (2024) Determinants and Biomarkers of Progression Independent of Relapses in Multiple Sclerosis Ann Neurol, 96(1): 1-20
  • Rommer P, Puchhammer‐Stöckl E, Lassmann H, Berger T, Vietzen H (2024) Ineffective control of Epstein–Barr virus infection is seen in MS: What is next? Clin Transl Med, 14 (2): :e1596
  • Kameneva P, Taschner-Mandl S (2024) In preprints: recapitulation of development and wound healing shapes the spatial organization of glioblastoma Development, 151 (1): dev202618

2023 Original Articles

  • Jacob T, Annusver K, Czarnewski P, Dalessandri T, Kalk C, Levra Levron C, Campamà Sanz N, Kastriti ME, Mikkola ML, Rendl M, Lichtenberger MB, Donati G , Björklund AK, Kasper M (2023) Molecular and spatial landmarks of early mouse skin development Development, 58(20) : 2140-2162.e5.
  • Gerschenfeld G, Coulpier F, Gresset A, Pulh P, Job B, Topilko T, Siegenthaler, Ph.D. J, Kastriti M, Brunet I, Charnay P, Topilko P (2023) Neural tube-associated boundary caps are a major source of mural cells in the skin eLife, 12
  • Mathias S, Adameyko I, Hellander A, Kursawe J (2023) Contributions of cell behavior to geometric order in embryonic cartilage PloS Computational Biology, 19 (11): e1011658
  • Gao T, Kastriti M, Ljungström V, Heinzel A, Tischler A, Oberbauer R, Loh P, Adameyko I, Park P, Kharchenko P (2023) A pan-tissue survey of mosaic chromosomal alterations in 948 individuals Nature Genetics, 55(11): )1901-1911
  • Samadzadeh S, Olesen M, Wirenfeldt M, Möller S, Misu T, Soelberg K, Frederiksen J, Heegaard S, Mariotto S, Fujihara K, Ruprecht K, Andersen T, Marignier R, Lillevang S, Flanagan E, Pittock S, Kim H, Bennett J, Paul F, Sorensen G, Weinshenker B, Lassmann H, Asgari N (2023) Microfibrillar-associated protein 4 as a potential marker of acute relapse in inflammatory demyelinating diseases of the central nervous system: Pathological and clinical aspects Mult Scler, 29(14): 1721-1735
  • Laddach A, Chng S, Lasrado R, Progatzky F, Shapiro M, Erickson A, Sampedro Castaneda M, Artemov A, Bon-Frauches A, Amaniti E, Kleinjung J, Boeing S, Ultanir S, Adameyko I, Pachnis V (2023) A branching model of lineage differentiation underpinning the neurogenic potential of enteric glia Nat Commun, 14 (1): 5904
  • Krupenko D, Miroliubov A, Kryukov E, Faure L, Minemizu R, Haag L, Lundgren M, Kameneva P, Kastriti M, Adameyko I (2023) Polymorphic parasitic larvae cooperate to build swimming colonies luring hosts Curr Biol., 33(20)4524-4531: 4524-4531
  • Gallus M, Roll W, Dik A, Barca C, Zinnhardt B, Hicking G, Mueller C, Naik V, Anstötz M, Krämer J, Rolfes L, Wachsmuth L, Pitsch J, van Loo K, Räuber S, Okada H, Wimberley C, Strippel C, Golombeck K, Johnen A, Kovac S, Groß C, Backhaus P, Seifert R, Lewerenz J, Surges R, Elger C, Wiendl H, Ruck T, Becker A, Faber C, Jacobs A, Bauer J, Meuth S, Schäfers M, Melzer N (2023) Translational imaging of TSPO reveals pronounced innate inflammation in human and murine CD8 T cell–mediated limbic encephalitis Sci Adv, 9 (23): eabq7595.
  • Krajnc N, Schmidbauer V, Leinkauf J, Haider L, Bsteh G, Kasprian G, Leutmezer F, Kornek B, Rommer P, Berger T, Lassmann H, Dal-Bianco A, Hametner S (2023) Paramagnetic rim lesions lead to pronounced diffuse periplaque white matter damage in multiple sclerosis Mult Scler, 29(11-12): 1406-1417
  • Martinović K, Bauer J, Kunze M, Berger J, Forss-Petter S (2023) Abcd1 deficiency accelerates cuprizone-induced oligodendrocyte loss and axonopathy in a demyelinating mouse model of X-linked adrenoleukodystrophy Acta Neuropathologica Communications, 11 (1): 98
  • Sunadome K, Erickson A, Kah D, Fabry B, Adori C, Kameneva P, Faure L, Kanatani S, Kaucka M, Dehnisch Ellström I, Tesarova M, Zikmund T, Kaiser J, Edwards S, Maki K, Adachi T, Yamamoto T, Fried K, Adameyko I (2023) Directionality of developing skeletal muscles is set by mechanical forces Nat Commun, 14 (1): 3060
  • Petersen J, Englmaier L, Artemov A, Poverennaya I, Mahmoud R, Bouderlique T, Tesarova M, Deviatiiarov R, Szilvásy-Szabó A, Akkuratov E, Pajuelo Reguera D, Zeberg H, Kaucka M, Kastriti M, Krivanek J, Radaszkiewicz T, Gömöryová K, Knauth S, Potesil D, Zdrahal Z, Ganji R, Grabowski A, Buhl M, Zikmund T, Kavkova M, Axelson H, Lindgren D, Kramann R, Kuppe C, Erdélyi F, Máté Z, Szabó G, Koehne T, Harkany T, Fried K, Kaiser J, Boor P, Fekete C, Rozman J, Kasparek P, Prochazka J, Sedlacek R, Bryja V, Gusev O, Adameyko I (2023) A previously uncharacterized Factor Associated with Metabolism and Energy (FAME/C14orf105/CCDC198/1700011H14Rik) is related to evolutionary adaptation, energy balance, and kidney physiology Nat Commun, 14 (1): 3092
  • Geeraerts T, Guilbeau-Frugier C, Garcia C, Memier V, Raposo N, Bonneville F, Gales C, Darcourt J, Voisin S, Ribes A, Piel-Julian M, Bounes F, Albucher J, Roux F, Izopet J, Telmon N, Olivot J, Sié P, Bauer J, Payrastre B, Liblau R (2023) Immunohistologic Features of Cerebral Venous Thrombosis Due to Vaccine-Induced Immune Thrombotic Thrombocytopenia Neurol Neuroimmunol Neuroinfl, 10 (4): e200127
  • Pegoretti V, Bauer J, Fischer R, Paro I, Douwenga W, Kontermann R, Pfizenmaier K, Houben E, Broux B, Hellings N, Baron W, Laman J, Eisel U (2023) Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS J Neuroinflammation, 20 (1): 106
  • Gonzalez-Fierro C, Fonte C, Dufourd E, Cazaentre V, Aydin S, Engelhardt B, Caspi R, Xu B, Martin-Blondel G, Spicer J, Trapani J, Bauer J, Liblau R, Bost C (2023) Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell–Mediated Neuroinflammation Neurol Neuroimmunol Neuroinfl, 10 (4): e200117
  • Li X, Andrusivova Z, Czarnewski P, Langseth C, Andersson A, Liu Y, Gyllborg D, Braun E, Larsson L, Hu L, Alekseenko Z, Lee H, Avenel C, Kallner H, Åkesson E, Adameyko I, Nilsson M, Linnarsson S, Lundeberg J, Sundström E (2023) Profiling spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin Nature Neurosci, 26(5): 891-901
  • Schwab J, Haider C, Kopp M, Zrzavy T, Endmayr V, Ricken G, Kubista H, Haider T, Liebscher T, Lübstorf T, Blex C, Serdani-Neuhaus L, Curt A, Cinelli P, Scivoletto G, Fehlings M, May C, Guntermann A, Marcus K, Meisel C, Dirnagl U, Martus P, Prüss H, Popovich P, Lassmann H, Höftberger R (2023) Lesional Antibody Synthesis and Complement Deposition Associate With De Novo Antineuronal Antibody Synthesis After Spinal Cord Injury Neurol Neuroimmunol Neuroinfl, 10 (3): e200099
  • Mader S, Ho S, Wong H, Baier S, Winklmeier S, Riemer C, Rübsamen H, Fernandez I, Gerhards R, Du C, Chuquisana O, Lünemann J, Lux A, Nimmerjahn F, Bradl M*, Kawakami N*, Meinl E* (* shared senior authorship) (2023) Dissection of complement and Fc-receptor-mediated pathomechanisms of autoantibodies to myelin oligodendrocyte glycoprotein PNAS, 120 (13): e2300648120
  • Dorninger F, Kiss A, Rothauer P, Stiglbauer-Tscholakoff A, Kummer S, Fallatah W, Perera-Gonzalez M, Hamza O, König T, Bober M, Cavallé-Garrido T, Braverman N, Forss-Petter S, Pifl C, Bauer J, Bittner R, Helbich T, Podesser B, Todt H, Berger J (2023) Overlapping and Distinct Features of Cardiac Pathology in Inherited Human and Murine Ether Lipid Deficiency Int J Mol Sci, 24 (3): 1884
  • Zakani M, Nigritinou M, Ponleitner M, Takai Y, Hofmann D, Hillebrand S, Höftberger R, Bauer J, Lasztoczi B, Misu T, Kasprian G, Rommer P, Bradl M (2023) Paths to hippocampal damage in neuromyelitis optica spectrum disorders Neuropathol Appl Neurobiol, 49 (2)
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  • Kalinowska‐Lyszczarz A, Tillema J, Tobin W, Guo Y, Weigand S, Metz I, Brück W, Lassmann H, Giraldo‐Chica M, Port J, Lucchinetti C (2023) Long‐term clinical, imaging and cognitive outcomes association with MS immunopathology Ann Clin Transl Neurol, 26(5): 891-901
  • Tröscher A, Mair K, de Juan L, Köck U, Steinmaurer A, Baier H, Becker A, Blümcke I, Finzel M, Geis C, Höftberger R, Mawrin C, von Oertzen T, Pitsch J, Surges R, Voges B, Weis S, Winklehner M, Woermann F, Bauer J, Bien C (2023) Temporal lobe epilepsy with GAD antibodies: neurons killed by T cells not by complement membrane attack complex Brain, 146(4): 1436-1452
  • Zhou C, Häneke T, Rohner E, Sohlmér J, Kameneva P, Artemov A, Adameyko I, Sahara M (2023) STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development Cardiovascular Res, 119(5): 1202-1217
  • Krajnc N, Dal-Bianco A, Leutmezer F, Kasprian G, Pemp B, Kornek B, Berger T, Rommer P, Hametner S, Lassmann H, Bsteh G (2023) Association of paramagnetic rim lesions and retinal layer thickness in patients with multiple sclerosis Mult Scler, 29(3): 374-384
  • Faure L, Soldatov R, Kharchenko P, Adameyko I (2023) scFates: a scalable python package for advanced pseudotime and bifurcation analysis from single-cell data Bioinformatics, : 39(1):btac746
  • Licht‐Mayer S, Campbell G, Mehta A, McGill K, Symonds A, Al‐Azki S, Pryce G, Zandee S, Zhao C, Kipp M, Smith K, Baker D, Altmann D, Anderton S, Kap Y, Laman J, t’Hart B, Rodriguez M, Franklin R, Chandran S, Lassmann H, Trapp B, Mahad D (2023) Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis Neuropathol Appl Neurobiol, 49(1): e12851

2023 Reviews

  • Kameneva P (2023) Pathway to Independence – an interview with Polina Kameneva Development, 150 (17): dev202261
  • Murtazina A, Adameyko I (2023) The peripheral nervous system Development, 150 (9): dev201164
  • Erickson A, Adameyko I (2023) hPSCs-derived Schwann cells serve for disease modeling and drug discovery Cell Stem Cell, 30 (5): 501-502
  • Adameyko I (2023) Evolutionary origin of the neural tube in basal deuterostomes Curr Biol., 33 (8): R319-R331
  • Bien C, Bauer J (2023) What neuropathology teaches us about autoimmune encephalitides, autoimmune epilepsies, and encephalomyelitides Clin Neuropathol, 42(3): 87-92
  • Krivanek J, Buchtova M, Fried K, Adameyko I (2023) Plasticity of Dental Cell Types in Development, Regeneration, and Evolution J Dent Res, 102(6): 589-598
  • Erickson A, Kameneva P, Adameyko I (2023) The transcriptional portraits of the neural crest at the individual cell level Semin Cell Dev Biol, : 138:68-80

2022 Original Articles

  • Artemov A, Zhenilo S, Kaplun D, Starshin A, Sokolov A, Mazur A, Szpotan J, Gawronski M, Modrzejewska M, Gackowski D, Prokhortchouk E (2022) An IDH-independent mechanism of DNA hypermethylation upon VHL inactivation in cancer Epigenetics, 17 (8): 894-905
  • Lomov N, Viushkov V, Ulianov S, Gavrilov A, Alexeyevsky D, Artemov A, Razin S, Rubtsov M (2022) Recurrent Translocations in Topoisomerase Inhibitor-Related Leukemia Are Determined by the Features of DNA Breaks Rather Than by the Proximity of the Translocating Genes Int J Mol Sci, 23 (17): 9824
  • Kaucka M, Joven Araus A, Tesarova M, Currie J, Boström J, Kavkova M, Petersen J, Yao Z, Bouchnita A, Hellander A, Zikmund T, Elewa A, Newton P, Fei J, Chagin A, Fried K, Tanaka E, Kaiser J, Simon A, Adameyko I (2022) Altered developmental programs and oriented cell divisions lead to bulky bones during salamander limb regeneration Nat Commun, 13 (1): 14;13(1):6949
  • Hametner S, Silvaieh S, Thurnher M, Dal-Bianco A, Cetin H, Ponleitner M, Zebenholzer K, Pemp B, Trattnig S, Rössler K, Berger T, Lassmann H, Hainfellner J, Bsteh G (2022) A case of primary optic pathway demyelination caused by oncocytic oligodendrogliopathy of unknown origin Acta Neuropathologica Communications, 10 (1): 160
  • Akkuratova N, Faure L, Kameneva P, Kastriti M, Adameyko I (2022) Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics Front Endocrinol, 13: 1020000.
  • Weinhofer I, Buda A, Kunze M, Palfi Z, Traunfellner M, Hesse S, Villoria-Gonzalez A, Hofmann J, Hametner S, Regelsberger G, Moser A, Eichler F, Kemp S, Bauer J, Kühl J, Forss-Petter S, Berger J (2022) Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response Commun Biol, 5 (1): 944
  • Winklehner M, Bauer J, Endmayr V, Schwaiger C, Ricken G, Motomura M, Yoshimura S, Shintaku H, Ishikawa K, Tsuura Y, Iizuka T, Yokota T, Irioka T, Höftberger R (2022) Paraneoplastic Cerebellar Degeneration With P/Q-VGCC vs Yo Autoantibodies Neurol Neuroimmunol Neuroinfl, 9 (4): e200006
  • Chuquisana O, Strippel C, Tröscher A, Baumgartner T, Rácz A, Keller C, Elger C, Melzer N, Kovac S, Wiendl H, Bauer J, Lünemann J (2022) Complement activation contributes to GAD antibody-associated encephalitis Acta Neuropathol, 144 (2): 381-383
  • Krajnc N, Bsteh G, Kasprian G, Zrzavy T, Kornek B, Berger T, Leutmezer F, Rommer P, Lassmann H, Hametner S, Dal-Bianco A (2022) Peripheral Hemolysis in Relation to Iron Rim Presence and Brain Volume in Multiple Sclerosis Front Neurol, 13: 928582
  • Kastriti M, Faure L, Von Ahsen D, Bouderlique T, Boström J, Solovieva T, Jackson C, Bronner M, Meijer D, Hadjab S, Lallemend F, Erickson A, Kaucka M, Dyachuk V, Perlmann T, Lahti L, Krivanek J, Brunet J, Fried K, Adameyko I (2022) Schwann cell precursors represent a neural crest‐like state with biased multipotency Embo Journ, : 41(17):e108780
  • Petitpré C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F (2022) Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification Nat Commun, 13 (1): 3878
  • Sriha J, Louis-Brennetot C, Pierre-Eugène C, Baulande S, Raynal V, Kramdi A, Adameyko I, Ernsberger U, Deller T, Delattre O, Janoueix-Lerosey I, Rohrer H (2022) BET and CDK Inhibition Reveal Differences in the Proliferation Control of Sympathetic Ganglion Neuroblasts and Adrenal Chromaffin Cells Cancers, 14 (11): 2755
  • Yizhou Hu, Yiwen Jiang, Jinan Behnan, Mariana Messias Ribeiro, Chrysoula Kalantzi, Ming-Dong Zhang, Daohua Lou, Martin Häring, Nilesh Sharma, Satoshi Okawa, Antonio Del Sol, Igor Adameyko, Mikael Svensson, Oscar Persson, Patrik Ernfors (2022) Neural network learning defines glioblastoma features to be of neural crest perivascular or radial glia lineages Sci Adv, : 8(23):eabm6340
  • Bernard-Valnet R, Frieser D, Nguyen X, Khajavi L, Quériault C, Arthaud S, Melzi S, Fusade-Boyer M, Masson F, Zytnicki M, Saoudi A, Dauvilliers Y, Peyron C, Bauer J, Liblau R (2022) Influenza vaccination induces autoimmunity against orexinergic neurons in a mouse model for narcolepsy Brain, : 145(6):2018-2030
  • Kameneva P, Melnikova V, Kastriti M, Kurtova A, Kryukov E, Murtazina A, Faure L, Poverennaya I, Artemov A, Kalinina T, Kudryashov N, Bader M, Skoda J, Chlapek P, Curylova L, Sourada L, Neradil J, Tesarova M, Pasqualetti M, Gaspar P, Yakushov V, Sheftel B, Zikmund T, Kaiser J, Fried K, Alenina N, Voronezhskaya E, Adameyko I (2022) Serotonin limits generation of chromaffin cells during adrenal organ development Nat Commun, 13 (1): 2901
  • Matula J, Polakova V, Salplachta J, Tesarova M, Zikmund T, Kaucka M, Adameyko I, Kaiser J (2022) Resolving complex cartilage structures in developmental biology via deep learning-based automatic segmentation of X-ray computed microtomography images Sci Rep, 12 (1): 8728
  • Bouderlique T, Petersen J, Faure L, Abed-Navandi D, Bouchnita A, Mueller B, Nazarov M, Englmaier L, Tesarova M, Frade P, Zikmund T, Koehne T, Kaiser J, Fried K, Wild C, Pantos O, Hellander A, Bythell J, Adameyko I (2022) Surface flow for colonial integration in reef-building corals Curr Biol., : 32(12):2596-2609
  • Steinkellner H, Kempaiah P, Beribisky A, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam J, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F (2022) TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome Int J Biol Macromol, 209: 972-983
  • Frieser D, Pignata A, Khajavi L, Shlesinger D, Gonzalez-Fierro C, Nguyen X, Yermanos A, Merkler D, Höftberger R, Desestret V, Mair K, Bauer J, Masson F, Liblau R (2022) Tissue-resident CD8+ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons Sci Transl Med, 14 (640)
  • Tesařová M, Mancini L, Mauri E, Aljančič G, Năpăruş-Aljančič M, Kostanjšek R, Bizjak Mali L, Zikmund T, Kaucká M, Papi F, Goyens J, Bouchnita A, Hellander A, Adameyko I, Kaiser J (2022) Living in darkness: Exploring adaptation of Proteus anguinus in 3 dimensions by X-ray imaging GigaScience, 11: giac030
  • Rauschmeier R, Reinhardt A, Gustafsson C, Glaros V, Artemov AV, Dunst J, Taneja R, Adameyko I, Månsson R, Busslinger M, Kreslavsky T.exp (2022) Bhlhe40 function in activated B and TFH cells restrains the GC reaction and prevents lymphomagenesis J Exp Med, 219(2): e20211406
  • Westerhout EM, Hamdi M, Stroeken P, Nowakowska NE, Lakeman A, van Arkel J, Hasselt NE, Bleijlevens B, Akogul N, Haneveld F, Chan A, van Sluis P, Zwijnenburg D, Volckmann R, van Noesel CJ, Adameyko I, van Groningen T, Koster J, Valentijn LJ, van Nes J, Versteeg R. (2022) Mesenchymal type neuroblastoma cells escape ALK inhibitors Cancer Res, 82(3): 484-496

2022 Reviews

  • Faure L, Techameena P, Hadjab S (2022) Emergence of neuron types Curr Opin Cell Biol, 79: 102133
  • Ineichen BV , Okar SV , Proulx ST, Engelhardt B , Lassmann H , Reich DS (2022) Perivascular spaces and their role in neuroinflammation Neuron, 110(21): 3566-3581
  • Giovannoni G, Vanderdonckt P, Hartung H, Lassmann H, Comi G (2022) EBV and multiple sclerosis: Setting the research agenda Mult Scler Relat Disord., 67: 104158
  • Höftberger R, Lassmann H, Berger T, Reindl M (2022) Pathogenic autoantibodies in multiple sclerosis — from a simple idea to a complex concept Nat Rev Neurol, : 18(11):681-688
  • Bradl M (2022) From astrocyte destruction to axon injury: watching lesion evolution in experimental neuromyelitis optica Brain, 145(5): 1581-1583
  • Vanderdonckt P, Aloisi F, Comi G, de Bruyn A, Hartung H, Huitinga I, Kuhlmann T, Lucchinetti C, Metz I, Reynolds R, Lassmann H (2022) Tissue donations for multiple sclerosis research: current state and suggestions for improvement Brain Commun, 4 (2)
  • Lassmann H (2022) The Contribution of Neuropathology to Multiple Sclerosis Research Eur J Neurol, : 29(9):2869-2877
  • Lassmann H (2022) Tumefactive Multiple Sclerosis or Inflammatory Demyelinating Disease with Large Lesions? Eur J Neurol, 29(3): 687-688

2021 Original Articles

  • Colin A, Micali G, Faure L, Cosentino Lagomarsino M, van Teeffelen S (2021) Two different cell-cycle processes determine the timing of cell division in Escherichia coli eLife, 10: e67495
  • Aschauer C, Jelencsics K, Hu K, Heinzel A, Gregorich M, Vetter J, Schaller S, Winkler S, Weinberger J, Pimenov L, Gualdoni G, Eder M, Kainz A, Troescher A, Regele H, Reindl-Schwaighofer R, Wekerle T, Huppa J, Sykes M, Oberbauer R (2021) Prospective Tracking of Donor-Reactive T-Cell Clones in the Circulation and Rejecting Human Kidney Allografts Front Immunol, 12: 750005
  • Dal-Bianco A, Schranzer R, Grabner G, Lanzinger M, Kolbrink S, Pusswald G, Altmann P, Ponleitner M, Weber M, Kornek B, Zebenholzer K, Schmied C, Berger T, Lassmann H, Trattnig S, Hametner S, Leutmezer F, Rommer P (2021) Iron Rims in Patients With Multiple Sclerosis as Neurodegenerative Marker? A 7-Tesla Magnetic Resonance Study Front Neurol, 12: 632749
  • Förster M, Nelke C, Räuber S, Lassmann H, Ruck T, Sormani MP, Signori A, Hartung HP, Küry P, Meuth SG, Kremer D (2021) Nitrosative Stress Molecules in Multiple Sclerosis: A Meta-Analysis Biomedicines, 9(12): 1899
  • Uçar M, Kamenev D, Sunadome K, Fachet D, Lallemend F, Adameyko I, Hadjab S, Hannezo E (2021) Theory of branching morphogenesis by local interactions and global guidance Nat Commun, 12 (1): 6830
  • Krivanek J, Lavicky J, Bouderlique T, Adameyko I (2021) Rapid Isolation of Single Cells from Mouse and Human Teeth J Vis Exp, (176)
  • Tröscher A, Sakaraki E, Mair K, Köck U, Racz A, Borger V, Cloppenborg T, Becker A, Bien C, Bauer J (2021) T cell numbers correlate with neuronal loss rather than with seizure activity in medial temporal lobe epilepsy Epilepsia, 62 (6): 1343-1353
  • Papazian I, Tsoukala E, Boutou A, Karamita M, Kambas K, Iliopoulou L, Fischer R, Kontermann R, Denis M, Kollias G, Lassmann H, Probert L (2021) Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKβ promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice J Neuroinflammation, 18 (1): 222.
  • Zrzavy T, Endmayr V, Bauer J, Macher S, Mossaheb N, Schwaiger C, Ricken G, Winklehner M, Glatter S, Breu M, Wimmer I, Kovacs G, Risser D, Klupp N, Simonitsch‐Klupp I, Roetzer T, Rommer P, Berger T, Gelpi E, Lassmann H, Graus F, Dalmau J, Höftberger R (2021) Neuropathological variability within a spectrum of NMDAR‐encephalitis. Ann Neurol, : 2021 Sep 25. doi: 10.1002/ana.26223. Online ahead of print.
  • Glaros V, Rauschmeier R, Artemov A, Reinhardt A, Ols S, Emmanouilidi A, Gustafsson C, You Y, Mirabello C, Björklund, Perez L, King N, Månsson R, Angeletti D, Loré K, Adameyko I, Busslinger M, Kreslavsky T (2021) Limited access to antigen drives generation of early B cell memory while restraining the plasmablast response Immunity, 54 (9): 2005-2023.e10
  • Tobin W, Kalinowska-Lyszczarz A, Weigand S, Guo Y, Tosakulwong N, Parisi J, Metz I, Frischer J, Lassmann H, Brück W, Linbo L, Lucchinetti C (2021) Clinical Correlation of Multiple Sclerosis Immunopathologic Subtypes Neurology, 97(19): e1906-e1913
  • Bedoya-Reina O, Li W, Arceo M, Plescher M, Bullova P, Pui H, Kaucka M, Kharchenko P, Martinsson T, Holmberg J, Adameyko I, Deng Q, Larsson C, Juhlin C, Kogner P, Schlisio S (2021) Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumors Nat Commun, 12 (1): 5309
  • Fleischer V, Gonzalez-Escamilla G, Ciolac D, Albrecht P, Küry P, Gruchot J, Dietrich M, Hecker C, Müntefering T, Bock S, Oshaghi M, Radetz A, Cerina M, Krämer J, Wachsmuth L, Faber C, Lassmann H, Ruck T, Meuth SG, Muthuraman M, Groppa S. (2021) Translational value of choroid plexus imaging for tracking neuroinflammation in mice and humans Proc Natl Acad Sci USA, 118(36): e2025000118
  • Marignier R, Hacohen Y, Cobo-Calvo A, Pröbstel A, Aktas O, Alexopoulos H, Amato M, Asgari N, Banwell B, Bennett J, Brilot F, Capobianco M, Chitnis T, Ciccarelli O, Deiva K, De Sèze J, Fujihara K, Jacob A, Kim H, Kleiter I, Lassmann H, Leite M, Linington C, Meinl E, Palace J, Paul F, Petzold A, Pittock S, Reindl M, Sato D, Selmaj K, Siva A, Stankoff B, Tintore M, Traboulsee A, Waters P, Waubant E, Weinshenker B, Derfuss T, Vukusic S, Hemmer B (2021) Myelin-oligodendrocyte glycoprotein antibody-associated disease Lancet Neurol, 20 (9): 762-772
  • Petersen MA, Tognatta R, Meyer-Franke A, Bushong EA, Mendiola AS, Yan Z, Muthusamy A, Merlini M, Meza-Acevedo R, Cabriga B, Zhou Y, Thomas R, Ryu JK, Lassmann H, Ellisman MH, Akassoglou K. (2021) BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis. Brain, 144(8): .2291-2301
  • Kaucka M, Szarowska B, Kavkova M, Kastriti M, Kameneva P, Schmidt I, Peskova L, Joven Araus A, Simon A, Kaiser J, Adameyko I (2021) Nerve-associated Schwann cell precursors contribute extracutaneous melanocytes to the heart, inner ear, supraorbital locations and brain meninges Cell Mol Life Sci, : 2021 Jul 18. doi: 10.1007/s00018-021-03885-9. Online ahead of print. PMID: 34274976
  • Metz I, Gavrilova R, Weigand S, Frischer J, Popescu B, Guo Y, Gloth M, Tobin W, Zalewski N, Lassmann H, Tillema J, Erickson B, Parisi J, Becker S, König F, Brück W, Lucchinetti C (2021) MRI Correlates of Multiple Sclerosis Immunopathological Patterns Ann Neurol, 90(3): 440-454
  • Kamenev D, Sunadome K, Shirokov M, Chagin A, Singh A, Irion U, Adameyko I, Fried K, Dyachuk V (2021) Schwann cell precursors generate sympathoadrenal system during zebrafish development J Neurosci Res, : 99(10)
  • Rodríguez-Pascau L, Vilalta A, Cerrada M, Traver E, Forss-Petter S, Weinhofer I, Bauer J, Kemp S, Pina G, Pascual S, Meya U, Musolino P, Berger J, Martinell M, Pizcueta P (2021) The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy Sci Transl Med, 13 (596): eabc0555
  • Häusler D, Akgün K, Stork L, Lassmann H, Ziemssen T, Brück W, Metz I. (2021) CNS inflammation after natalizumab therapy for multiple sclerosis: A retrospective histopathological and CSF cohort study Brain Pathol, 31(6): e12969
  • Kameneva P, V.Artemov A, Kastriti M, Sundström E, Kharchenko P, Adameyko I (2021) Evolutionary switch in expression of key markers between mouse and human leads to mis-assignment of cell types in developing adrenal medulla Cancer Cell, 39(5): 590-591
  • Kameneva P, Artemov A, Kastriti M, Faure L, Olsen T, Otte J, Erickson A, Semsch B, Andersson E, Ratz M, Frisén J, Tischler A, de Krijger R, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundström E, Mei S, Kogner P, Baryawno N, Kharchenko P, Adameyko I (2021) Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin Nature Genetics, : 53(5)
  • Takai Y, Misu T, Suzuki H, Takahashi T, Okada H, Tanaka S, Okita K, Sasou S, Watanabe M, Namatame C, Matsumoto Y, Ono H, Kaneko K, Nishiyama S, Kuroda H, Nakashima I, Lassmann H, Fujihara K, Itoyama Y, Aoki M (2021) Staging of astrocytopathy and complement activation in neuromyelitis optica spectrum disorders Brain, 144: 2401-2415
  • Doss P, Umair M, Baillargeon J, Fazazi R, Fudge N, Akbar I, Yeola A, Williams J, Leclercq M, Joly-Beauparlant C, Beauchemin P, Ruda G, Alpaugh M, Anderson A, Brennan P, Droit A, Lassmann H, Moore C, Rangachari M (2021) Male sex chromosomal complement exacerbates the pathogenicity of Th17 cells in a chronic model of central nervous system autoimmunity Cell Rep, 34 (10): 108833
  • Hamminger P, Marchetti L, Preglej T, Platzer R, Zhu C, Kamnev A, Rica R, Stolz V, Sandner L, Alteneder M, Kaba E, Waltenberger D, Huppa J, Trauner M, Bock C, Lyck R, Bauer J, Dupré L, Seiser C, Boucheron N, Engelhardt B, Ellmeier W (2021) Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases J Autoimmun, 119: 102610
  • Matula J, Tesarova M, Zikmund T, Kaucka M, Adameyko I, Kaiser J (2021) X-ray microtomography–based atlas of mouse cranial development GigaScience, 10 (3)
  • Cubas-Núñez L, Gil-Perotín S, Castillo-Villalba J, López V, Solís Tarazona L, Gasqué-Rubio R, Carratalá-Boscá S, Alcalá-Vicente C, Pérez-Miralles F, Lassmann H, Casanova B (2021) Potential Role of CHI3L1+ Astrocytes in Progression in MS Neurol Neuroimmunol Neuroinfl, 8 (3): e972
  • Dal-Bianco A, Grabner G, Kronnerwetter C, Weber M, Kornek B, Kasprian G, Berger T, Leutmezer F, Rommer P, Trattnig S, Lassmann H, Hametner S (2021) Long-term evolution of multiple sclerosis iron rim lesions in 7 T MRI Brain, 144(3): 833-847
  • Zrzavy T, Schwaiger C, Wimmer I, Berger T, Bauer J, Butovsky O, Schwab J, Lassmann H, Höftberger R (2021) Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury Brain, 144(1): 144-161
  • Tham M, Frischer J, Weigand S, Fitz‐Gibbon P, Webb S, Guo Y, Adiele R, Robinson C, Brück W, Lassmann H, Furber K, Pushie M, Parisi J, Lucchinetti C, Popescu B (2021) Iron heterogeneity in early active multiple sclerosis lesions Ann Neurol, 89(3): 498-510
  • Beltrán E+, Paunovic M+, Gebert D, Cesur E, Jeitler M, Höftberger R, Malotka J, Mader S, Kawakami N, Meinl E, Bradl M*, Dornmair K*, Lassmann H* + sharing co-first; *sharing senior authorship (2021) Archeological neuroimmunology: resurrection of a pathogenic immune response from a historical case sheds light on human autoimmune encephalomyelitis and multiple sclerosis Acta Neuropathol, 141(1): 67-83
  • Wimmer I, Scharler C, Kadowaki T, Hillebrand S, Scheiber‐Mojdehkar B, Ueda S, Bradl M, Berger T, Lassmann H, Hametner S (2021) Iron accumulation in the choroid plexus, ependymal cells and CNS parenchyma in a rat strain with low‐grade haemolysis of fragile macrocytic red blood cells Brain Pathol, 31(2): 333-345
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  • Zhao J, Faure L, Adameyko I, Sharpe PT (2021) Stem cell contributions to cementoblast differentiation in healthy periodontal ligament and periodontitis Stem Cells, 39(1): 92-102

2021 Reviews

  • Wiendl H, Gross C, Bauer J, Merkler D, Prat A, Liblau R (2021) Fundamental mechanistic insights from rare but paradigmatic neuroimmunological diseases Nat Rev Neurol, 17 (7): 433-447
  • Schwabenland M, Brück W, Priller J, Stadelmann C, Lassmann H, Prinz M (2021) Analyzing microglial phenotypes across neuropathologies: a practical guide Acta Neuropathol, 142(6): 923-936.
  • Baert L, Marignier R, Lassmann H, Huard B (2021) Case Report: In Situ Expression of a Proliferation-Inducing Ligand in Neuromyelitis Optica Front Neurol, 12: e721877
  • Dal-Bianco A, Höftberger R, Lassmann H, Berger T (2021) Kurt Jellinger 90: his contribution to neuroimmunology J Neural Transm, 128(10): 1545-1550
  • Cree B, Arnold D, Chataway J, Chitnis T, Fox R, Ramajo A, Murphy N, Lassmann H (2021) Secondary Progressive Multiple Sclerosis: New Insights Neurology, 97(8): 378-388
  • Comi G, Bar‐Or A, Lassmann H, Uccelli A, Hartung H, Montalban X, Sørensen P, Hohlfeld R, Hauser S, Absinta M, Battistini L, Bennet J, Bergman J, Calabrese M, Correale J, Dornmair K, Moiola L, Edan G, Fujihara K, Gastaldi M, Ghezzi A, Gommerman J, Hausler D, Hoftberger R, Kappos L, Sörensen P, Klotz L, Leocani L, Magliozzi R, Michel L, Meinl E, Misu T, Palace J, Prat A, Rocca M, Selmaj K, (2021) The role of B cells in Multiple Sclerosis and related disorders Ann Neurol, 89(1): 13-23
  • Kameneva P, Kastriti M, Adameyko I (2021) Neuronal lineages derived from the nerve-associated Schwann cell precursors Cell Mol Life Sci, 78(2): 513-529

2021 Book Chapters

  • Lassmann, Hans (2021) Pathophysiological Bases of Autoimmune-Initiated/Mediated Neurodegeneration. In: Sergiu Groppa and Sven G. Meuth: , Translational Methods for Multiple Sclerosis Research Springer Nature, Cham Switzerland: 3-12

2020 Original Articles

  • Albergante L, Mirkes E, Bac J, Chen H, Martin A, Faure L, Barillot E, Pinello L, Gorban A, Zinovyev A (2020) Robust and Scalable Learning of Complex Intrinsic Dataset Geometry via ElPiGraph Entropy, 22 (3): 296
  • Dagkonaki A, Avloniti M, Evangelidou M, Papazian I, Kanistras I, Tseveleki V, Lampros F, Tselios T, Jensen L, Möbius W, Ruhwedel T, Androutsou M, Matsoukas J, Anagnostouli M, Lassmann H, Probert L (2020) Mannan-MOG35-55 Reverses Experimental Autoimmune Encephalomyelitis, Inducing a Peripheral Type 2 Myeloid Response, Reducing CNS Inflammation, and Preserving Axons in Spinal Cord Lesions Front Immunol, 11: 575451
  • Gerhards R, Pfeffer L, Lorenz J, Starost L, Nowack L, Thaler F, Schlüter M, Rübsamen H, Macrini C, Winklmeier S, Mader S, Bronge M, Grönlund H, Feederle R, Hsia H, Lichtenthaler S, Merl-Pham J, Hauck S, Kuhlmann T, Bauer I, Beltran E, Gerdes L, Mezydlo A, Bar-Or A, Banwell B, Khademi M, Olsson T, Hohlfeld R, Lassmann H, Kümpfel T, Kawakami N, Meinl E (2020) Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS Acta Neuropathologica Communications, 8 (1): 207
  • Xie M, Gol'din P, Herdina AN, Estefa J, Medvedeva EV, Li L, Newton PT, Kotova S, Shavkuta B, Saxena A, Shumate LT, Metscher BD, Großschmidt K, Nishimori S, Akovantseva A, Usanova AP, Kurenkova AD, Kumar A, Arregui IL, Tafforeau P, Fried K, Carlström M, Simon A, Gasser C, Kronenberg HM, Bastepe M, Cooper KL, Timashev P, Sanchez S, Adameyko I, Eriksson A, Chagin AS. (2020) Secondary ossification center induces and protects growth plate structure eLife, 9: e55212
  • Krivanek J, Soldatov R, Kastriti M, Chontorotzea T, Herdina A, Petersen J, Szarowska B, Landova M, Matejova V, Holla L, Kuchler U, Zdrilic I, Vijaykumar A, Balic A, Marangoni P, Klein O, Neves V, Yianni V, Sharpe P, Harkany T, Metscher B, Bajénoff M, Mina M, Fried K, Kharchenko P, Adameyko I (2020) Dental cell type atlas reveals stem and differentiated cell types in mouse and human teeth Nat Commun, 11 (1): 4816
  • Faure L, Wang Y, Kastriti M, Fontanet P, Cheung K, Petitpré C, Wu H, Sun L, Runge K, Croci L, Landy M, Lai H, Consalez G, de Chevigny A, Lallemend F, Adameyko I, Hadjab S (2020) Single cell RNA sequencing identifies early diversity of sensory neurons forming via bi-potential intermediates Nat Commun, 11 (1): 4175
  • Eggers C, Kopatz V, Dörr W, Lassmann H, Geinitz H (2020) Localised multiple sclerosis-like disease after irradiation of the cervicothoracic spinal cord Mult Scler Relat Disord., 45: 102443
  • Klimovich A, Giacomello S, Björklund A, Faure L, Kaucka M, Giez C, Murillo-Rincon A, Matt A, Willoweit-Ohl D, Crupi G, de Anda J, Wong G, D’Amato M, Adameyko I, Bosch T (2020) Prototypical pacemaker neurons interact with the resident microbiota Proc Natl Acad Sci USA, 117(30): 17854-17863
  • Licht-Mayer S, Campbell G, Canizares M, Mehta A, Gane A, McGill K, Ghosh A, Fullerton A, Menezes N, Dean J, Dunham J, Al-Azki S, Pryce G, Zandee S, Zhao C, Kipp M, Smith K, Baker D, Altmann D, Anderton S, Kap Y, Laman J, Hart B, Rodriguez M, Watzlawick R, Schwab J, Carter R, Morton N, Zagnoni M, Franklin R, Mitchell R, Fleetwood-Walker S, Lyons D, Chandran S, Lassmann H, Trapp B, Mahad D (2020) Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis Acta Neuropathol, 140(2): 143-167
  • Zhang Y, Kameneva P, Annusver K, Kasper M, Chagin A, Adameyko I, Xie M (2020) Cruciate ligament, patellar tendon, and patella formation involves differential cellular sources and dynamics as joint cavitation proceeds Dev Dyn, 249(6): 711-722
  • Zierfuss B, Weinhofer I, Kühl J, Köhler W, Bley A, Zauner K, Binder J, Martinović K, Seiser C, Hertzberg C, Kemp S, Egger G, Leitner G, Bauer J, Wiesinger C, Kunze M, Forss-Petter S, Berger J (2020) Vorinostat in the acute neuroinflammatory form of X-linked adrenoleukodystrophy Ann Clin Transl Neurol, 7 (5): 639-652
  • Kuehn J, Scheuerle A, Bauer J, Becker A, Wirtz R, Lewerenz J (2020) A 64‐Year‐Old Patient With a Mesiotemporal Mass and Symptomatic Epilepsy Brain Pathol, 30 (2): 413-414
  • Malviya M, Saoudi A, Bauer J, Fillatreau S, Liblau R (2020) Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells J Autoimmun, 108: 102401
  • Takai Y, Misu T, Kaneko K, Chihara N, Narikawa K, Tsuchida S, Nishida H, Komori T, Seki M, Komatsu T, Nakamagoe K, Ikeda T, Yoshida M, Takahashi T, Ono H, Nishiyama S, Kuroda H, Nakashima I, Suzuki H, Bradl M, Lassmann H, Fujihara K, Aoki M; Japan MOG-antibody Disease Consortium. (2020) Myelin oligodendrocyte glycoprotein antibody-associated disease: an immunopathological study Brain, 143(5):: 1431-1446
  • Zhang Y, Annusver K, Sunadome K, Kameneva P, Edwards S, Lei G, Kasper M, Chagin A, Adameyko I, Xie M (2020) Epiphyseal Cartilage Formation Involves Differential Dynamics of Various Cellular Populations During Embryogenesis Front Cell Dev Biol, 8: 22
  • Romanov R, Tretiakov E, Kastriti M, Zupancic M, Häring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews W, Parnavelas J, Farlik M, Bock C, Adameyko I, Hökfelt T, Keimpema E, Harkany T (2020) Molecular design of hypothalamus development Nature, 582(7811): 246-252
  • Sierra R, Gómez Bustillo S, Kameneva P, Fiore E, Mazzone G, Borda M, Blanco M, Usuardi C, Furlan A, Ernfors P, Alaniz L, Montaner A, Adameyko I, Aquino J (2020) Contribution of neural crest and GLAST + Wnt1 + bone marrow pericytes with liver fibrogenesis and/or regeneration Liver Int, 40 (4): 977-987
  • Tsymala I, Nigritinou M, Zeka B, Schulz R, Niederschick F, Matković M, Bauer I, Szalay M, Schanda K, Lerch M, Misu T, Fujihara K, Bennett J, Dahle C, Pache F, Rommer P, Leutmezer F, Illes Z, Leite M, Palace J, Scholze P, Reindl M, Lassmann H, Bradl M (2020) Induction of aquaporin 4-reactive antibodies in Lewis rats immunized with aquaporin 4 mimotopes Acta Neuropathologica Communications, 15; 8 (1)
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  • Gödel C, Kunkel B, Kashani A, Lassmann H, Arumugam M, Krishnamoorthy G (2020) Perturbation of gut microbiota decreases susceptibility but does not modulate ongoing autoimmune neurological disease J Neuroinflammation, 17 (1): 79
  • Höftberger R, Guo Y, Flanagan E, Lopez-Chiriboga A, Endmayr V, Hochmeister S, Joldic D, Pittock S, Tillema J, Gorman M, Lassmann H, Lucchinetti C (2020) The pathology of central nervous system inflammatory demyelinating disease accompanying myelin oligodendrocyte glycoprotein autoantibody Acta Neuropathol, 139(5): 875-892
  • Klinger M, Zugmaier G, Nägele V, Goebeler M, Brandl C, Stelljes M, Lassmann H, von Stackelberg A, Bargou R, Kufer P (2020) Adhesion of T cells to endothelial cells facilitates blinatumomab-associated neurologic adverse events Cancer Res, 80 (1) : 91-101

2020 Reviews

  • Kastriti M, Kameneva P, Adameyko I (2020) Stem cells, evolutionary aspects and pathology of the adrenal medulla: A new developmental paradigm Mol Cell Endocrinol, 518: 110998
  • Filippi M, Preziosa P, Langdon D, Lassmann H, Paul F, Rovira A, Schoonheim M, Solari A, Stankoff B, Rocca M (2020) Identifying Progression In Multiple Sclerosis: New Perspectives Ann Neurol, 88(3): 438-452
  • Absinta M, Lassmann H, Trapp B (2020) Mechanisms underlying progression in multiple sclerosis Curr Opin Neurol, 33(3): 277-285.
  • Lassmann H (2020) Pathology of inflammatory diseases of the nervous system: Human disease versus animal models Glia, 68 (4): 830-844

2020 Book Chapters

  • Adameyko, I and Eames, BF (2020) Evolving Neural Crest Cells: Hopes for Present and Future Understanding. In: Brian F. Eames, Daniel Meulemans Medeiros and Igor Adameyko, Evolving Neural Crest Cells; CRC Press - Taylor & Francis Group, Boca Raton, London, New York : 265-274
  • Adameyko, I (2020) Elaboration of Fates in Neural Crest Lineage. In: Brian F. Eames, Daniel Meulemans Medeiros and Igor Adameyko, Evolving Neural Crest Cells; CRC Press - Taylor & Francis Group, Boca Raton, London, New York : 157-183
  • Höftberger R, Lassmann H (2020) Acute Disseminated Encephalomyelitis and Acute Hemorrhagic Leukoencephalomyelitis. In: Fabrice Chretien, Infections of the Central Nervous System: Pathology and Genetics John Wiley & Sons, Inc; Oxford, UK, Hoboken, USA: 251-257

2019 Original Articles

  • Prakash V, Carson B, Feenstra J, Dass R, Sekyrova P, Hoshino A, Petersen J, Guo Y, Parks M, Kurylo C, Batchelder J, Haller K, Hashimoto A, Rundqivst H, Condeelis J, Allis C, Drygin D, Nieto M, Andäng M, Percipalle P, Bergh J, Adameyko I, Farrants A, Hartman J, Lyden D, Pietras K, Blanchard S, Vincent C (2019) Ribosome biogenesis during cell cycle arrest fuels EMT in development and disease Nat Commun, 10 (1)
  • Newton P, Li L, Zhou B, Schweingruber C, Hovorakova M, Xie M, Sun X, Sandhow L, Artemov A, Ivashkin E, Suter S, Dyachuk V, El Shahawy M, Gritli-Linde A, Bouderlique T, Petersen J, Mollbrink A, Lundeberg J, Enikolopov G, Qian H, Fried K, Kasper M, Hedlund E, Adameyko I, Sävendahl L, Chagin A (2019) A radical switch in clonality reveals a stem cell niche in the epiphyseal growth plate Nature, 567 (7747): 234-238
  • Soldatov R, Kaucka M, Kastriti M, Petersen J, Chontorotzea T, Englmaier L, Akkuratova N, Yang Y, Häring M, Dyachuk V, Bock C, Farlik M, Piacentino M, Boismoreau F, Hilscher M, Yokota C, Qian X, Nilsson M, Bronner M, Croci L, Hsiao W, Guertin D, Brunet J, Consalez G, Ernfors P, Fried K, Kharchenko P, Adameyko I (2019) Spatiotemporal structure of cell fate decisions in murine neural crest Science, 364 (6444): eaas9536
  • Anaby D, Morozov D, Seroussi I, Hametner S, Sochen N, Cohen Y (2019) Single‐ and double‐Diffusion encoding MRI for studying ex vivo apparent axon diameter distribution in spinal cord white matter NMR Biomed, 32 (12): e4170
  • Bergner C, Meer F, Winkler A, Wrzos C, Türkmen M, Valizada E, Fitzner D, Hametner S, Hartmann C, Pfeifenbring S, Stoltenburg‐Didinger G, Brück W, Nessler S, Stadelmann C (2019) Microglia damage precedes major myelin breakdown in X‐linked adrenoleukodystrophy and metachromatic leukodystrophy Glia, 67 (6): 1196-1209
  • Gross C, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher A, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud D, Loussouarn D, Parratt J, Barnett M, Buckland M, Hardy T, Reddel S, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth S, Martin-Blondel G, Wiendl H, Liblau R (2019) CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome Nat Commun, 10 (1): 5779
  • Magliozzi R, Hametner S, Facchiano F, Marastoni D, Rossi S, Castellaro M, Poli A, Lattanzi F, Visconti A, Nicholas R, Reynolds R, Monaco S, Lassmann H, Calabrese M (2019) Iron homeostasis, complement, and coagulation cascade as CSF signature of cortical lesions in early multiple sclerosis Ann Clin Transl Neurol, 6(11): 2150-2163
  • Konjevic Sabolek M, Held K, Beltrán E, Niedl A, Meinl E, Hohlfeld R, Lassmann H, Dornmair K (2019) Communication of CD 8 + T cells with mononuclear phagocytes in multiple sclerosis Ann Clin Transl Neurol, 6(7): 1151-1164
  • Hernández-Torres E, Wiggermann V, Machan L, Sadovnick A, Li D, Traboulsee A, Hametner S, Rauscher A (2019) Increased mean R2* in the deep gray matter of multiple sclerosis patients: Have we been measuring atrophy? J Magn Reson Imaging, 50 (1): 201-208
  • Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller W, Lassmann H, Engelhardt B (2019) PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation Front Immunol, 10: 711
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  • Yshii L, Pignolet B, Mauré E, Pierau M, Brunner-Weinzierl M, Hartley O, Bauer J, Liblau R (2019) IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration JCI Insight, 4 (7)
  • Bernard-Valnet R, Cobo-Calvo A, Siegfried A, Marasescu R, Bonnan M, Ballan G, Ellie E, Bauer J, Uro-Coste E, Marignier R, Brassat D (2019) Paraneoplastic neuromyelitis optica and ovarian teratoma: A case series Mult Scler Relat Disord., 31: 97-100
  • Wimmer I, Scharler C, Zrzavy T, Kadowaki T, Mödlagl V, Rojc K, Tröscher A, Kitic M, Ueda S, Bradl M, Lassmann H (2019) Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis Acta Neuropathologica Communications, 7 (1): 14
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  • Haindl M, Köck U, Zeitelhofer-Adzemovic M, Fazekas F, Hochmeister S (2019) The formation of a glial scar does not prohibit remyelination in an animal model of multiple sclerosis Glia, 67 (3): 467-481
  • Tröscher A, Wimmer I, Quemada-Garrido L, Köck U, Gessl D, Verberk S, Martin B, Lassmann H, Bien C, Bauer J (2019) Microglial nodules provide the environment for pathogenic T cells in human encephalitis Acta Neuropathol, 137(4): 137(4):619-635
  • Baert L, Benkhoucha M, Popa N, Ahmed M, Manfroi B, Boutonnat J, Sturm N, Raguenez G, Tessier M, Casez O, Marignier R, Ahmadi M, Broisat A, Ghezzi C, Rivat C, Sonrier C, Hahne M, Baeten D, Vives R, Lortat-Jacob H, Marche P, Schneider P, Lassmann H, Boucraut J, Lalive P, Huard B (2019) APRIL-mediated anti-inflammatory response of astrocytes in multiple sclerosis Ann Neurol, 85(3): 406-420
  • Hillebrand S, Schanda K, Nigritinou M, Tsymala I, Böhm D, Peschl P, Takai Y, Fujihara K, Nakashima I, Misu T, Reindl M, Lassmann H, Bradl M (2019) Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat Acta Neuropathol, 137(3): 467-485
  • Heckova E, Strasser B, Hangel G, Považan M, Dal-Bianco A, Rommer P, Bednarik P, Gruber S, Leutmezer F, Lassmann H, Trattnig S, Bogner W (2019) 7 T Magnetic Resonance Spectroscopic Imaging in Multiple Sclerosis Invest Radiol, 54(4): 247-254
  • Kau T, Hametner S, Endmayr V, Deistung A, Prihoda M, Haimburger E, Menard C, Haider T, Höftberger R, Robinson S, Reichenbach J, Lassmann H, Traxler H, Trattnig S, Grabner G (2019) Microvessels may Confound the “Swallow Tail Sign” in Normal Aged Midbrains: A Postmortem 7 T SW-MRI Study J Neuroimaging, 29(1): 65-69
  • Zrzavy T, Höftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, Lassmann H (2019) Pro-inflammatory Activation of Microglia in the Brain of Patients with Sepsis Neuropathol Appl Neurobiol, 45(3): 278-290

2019 Reviews

  • Zrzavy T, Kollaritsch H, Rommer P, Boxberger N, Loebermann M, Wimmer I, Winkelmann A, Zettl U (2019) Vaccination in Multiple Sclerosis: Friend or Foe? Front Immunol, 10
  • Titulaer M, Irani S, Lassmann H (2019) PDE10A antibodies in autoimmune encephalitis Neurology, 93(8): 327-328
  • Lassmann H (2019) The changing concepts in the neuropathology of acquired demyelinating central nervous system disorders. Curr Opin Neurol, 32(3): 313-319
  • Lassmann H (2019) Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis Front Immunol, 9: 3116
  • Ciccarelli O, Cohen J, Reingold S, Weinshenker B, Amato M, Banwell B, Barkhof F, Bebo B, Becher B, Bethoux F, Brandt A, Brownlee W, Calabresi P, Chatway J, Chien C, Chitnis T, Ciccarelli O, Cohen J, Comi G, Correale J, De Sèze J, De Stefano N, Fazekas F, Flanagan E, Freedman M, Fujihara K, Galetta S, Goldman M, Greenberg B, Hartung H, Hemmer B, Henning A, Izbudak I, Kappos L, Lassmann H, Laule C, Levy M, Lublin F, Lucchinetti C, Lukas C, Marrie R, Miller A, Miller D, Montalban X, Mowry E, Ourselin S, Paul F, Pelletier D, Ranjeva J, Reich D, Reingold S, Rocca M, Rovira A, Schlaerger R, Soelberg Sorensen P, Sormani M, Stuve O, Thompson A, Tintoré M, Traboulsee A, Trapp B, Trojano M, Uitdehaag B, Vukusic S, Waubant E, Weinshenker B, Wheeler-Kingshott C, Xu J (2019) Spinal cord involvement in multiple sclerosis and neuromyelitis optica spectrum disorders Lancet Neurol, 18 (2): 185-197

2018 Original Articles

  • Kap Y, Bus-Spoor C, van Driel N, Dubbelaar M, Grit C, Kooistra S, Fagrouch Z, Verschoor E, Bauer J, Eggen B, Harmsen H, Laman J, ’t Hart B (2018) Targeted Diet Modification Reduces Multiple Sclerosis–like Disease in Adult Marmoset Monkeys from an Outbred Colony J Immunol, 201 (11): 3229-3243
  • Reinthaler E, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill C, Hoffjan S, Epplen J, Zettl U, Hecker M, Deutschländer A, Meuth S, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick A, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A (2018) TPP2 mutation associated with sterile brain inflammation mimicking MS Neurol Genet, 4 (6): e285
  • Rubino S, Mayo L, Wimmer I, Siedler V, Brunner F, Hametner S, Madi A, Lanser A, Moreira T, Donnelly D, Cox L, Rezende R, Butovsky O, Lassmann H, Weiner H (2018) Acute microglia ablation induces neurodegeneration in the somatosensory system Nat Commun, 9 (1): 4578
  • Martin N, Nawrocki A, Molnar V, Elkjaer M, Thygesen E, Palkovits M, Acs P, Sejbaek T, Nielsen H, Hegedus Z, Sellebjerg F, Molnar T, Barbosa E, Alcaraz N, Gallyas F, Svenningsen A, Baumbach J, Lassmann H, Larsen M, Illes Z (2018) Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes PlosOne, 13 (8): e0202530
  • Spadaro M, Winklmeier S, Beltrán E, Macrini C, Höftberger R, Schuh E, Thaler F, Gerdes L, Laurent S, Gerhards R, Brändle S, Dornmair K, Breithaupt C, Krumbholz M, Moser M, Kirshnamoorthy G, Kamp F, Jenne D, Hohlfeld R, Kümpfel T, Lassmann H, Kawakami N, Meinl E (2018) Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein Ann Neurol, 84(2): 315-328
  • Hametner S, Endmayr V, Deistung A, Palmrich P, Prihoda M, Haimburger E, Menard C, Feng X, Haider T, Leisser M, Köck U, Kaider A, Höftberger R, Robinson S, Reichenbach JR, Lassmann H, Traxler H, Trattnig S, Grabner G. (2018) The influence of brain iron and myelin on magnetic susceptibility and effective transverse relaxation - A biochemical and histological validation study Neuroimage, 179: 117-133.
  • Weinhofer I, Zierfuss B, Hametner S, Wagner M, Popitsch N, Machacek C, Bartolini B, Zlabinger G, Ohradanova-Repic A, Stockinger H, Köhler W, Höftberger R, Regelsberger G, Forss-Petter S, Lassmann H, Berger J (2018) Impaired plasticity of macrophages in X-linked adrenoleukodystrophy Brain, 141: 2329-2342
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  • Machado-Santos J, Saji E, Tröscher A, Paunovic M, Liblau R, Gabriely G, Bien C, Bauer J, Lassmann H (2018) The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells Brain, 141(7): 2066-2082
  • Blaabjerg M, Hemdrup A, Drici L, Ruprecht K, Garred P, Höftberger R, Kristensen B, Kondziella D, Sejbaek T, Hansen S, Nielsen H, Jensen P, Meyer M, Paul F, Lassmann H, Larsen M, Illes Z (2018) Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS) Front Immunol, 9: 741
  • Wimmer I, Tröscher A, Brunner F, Rubino S, Bien C, Weiner H, Lassmann H, Bauer J (2018) Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples Sci Rep, 8 (1): 6351
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  • Bagnato F, Hametner S, Franco G, Pawate S, Sriram S, Lassmann H, Gore J, Smith S, Dortch R (2018) Selective Inversion Recovery Quantitative Magnetization Transfer Brain MRI at 7T: Clinical and Postmortem Validation in Multiple Sclerosis J Neuroimaging, 28(4) : 380-388
  • Martin N, Molnar V, Szilagyi G, Elkjaer M, Nawrocki A, Okarmus J, Wlodarczyk A, Thygesen E, Palkovits M, Gallyas F, Larsen M, Lassmann H, Benedikz E, Owens T, Svenningsen A, Illes Z (2018) Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice Front Immunol, 9: 490
  • Bagnato F, Hametner S, Boyd E, Endmayr V, Shi Y, Ikonomidou V, Chen G, Pawate S, Lassmann H, Smith S, Welch E (2018) Untangling the R2* contrast in multiple sclerosis: A combined MRI-histology study at 7.0 Tesla PlosOne, 13 (3): e0193839
  • Schweser F, Raffaini Duarte Martins A, Hagemeier J, Lin F, Hanspach J, Weinstock-Guttman B, Hametner S, Bergsland N, Dwyer M, Zivadinov R (2018) Mapping of thalamic magnetic susceptibility in multiple sclerosis indicates decreasing iron with disease duration: A proposed mechanistic relationship between inflammation and oligodendrocyte vitality Neuroimage, 167: 438-452
  • Zrzavy T, Machado-Santos J, Christine S, Baumgartner C, Weiner H, Butovsky O, Lassmann H (2018) Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts Brain Pathol, 28(6): 791-805
  • Lemke A, Ferguson J, Gross K, Penzenstadler C, Bradl M, Mayer R, Gerner C, Redl H, Wolbank S (2018) Transplantation of human amnion prevents recurring adhesions and ameliorates fibrosis in a rat model of sciatic nerve scarring Acta Biomater, 66: 335–349

2018 Reviews

  • Lassmann H (2018) Multiple Sclerosis Pathology and its Reflection by Imaging Technologies: Introduction Brain Pathol, 28 (5): 721-722
  • Wimmer I, Zrzavy T, Lassmann H (2018) Neuroinflammatory responses in experimental and human stroke lesions J Neuroimmunol, 323: 10-18
  • Hametner S, Bianco AD, Trattnig S, Lassmann H. (2018) Iron related changes in MS lesions and their validity to characterize MS lesion types and dynamics with Ultra-high field magnetic resonance imaging Brain Pathol, 28(5): 743-749
  • Bradl M, Reindl M, Lassmann H (2018) Mechanisms for lesion localization in neuromyelitis optica spectrum disorders Curr Opin Neurol, 31(3): 325-333
  • O’Loughlin E, Madore C, Lassmann H, Butovsky O (2018) Microglial Phenotypes and Functions in Multiple Sclerosis Cold Spring Harb Perspect Med., 8 (2): a028993
  • Lassmann H (2018) Multiple Sclerosis Pathology Cold Spring Harb Perspect Med., 8(3): a028936

2017 Original Articles

  • Furlan A, Dyachuk V, Kastriti M, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko P, Ernfors P, Adameyko I (2017) Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla Science, 357 (6346): eaal3753
  • Gebauer C, Pignolet B, Yshii L, Mauré E, Bauer J, Liblau R (2017) CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model Oncoimmunology, 6 (2): e1260212
  • Dunham J, van de Vis R, Bauer J, Wubben J, van Driel N, Laman J, ‘t Hart B, Kap Y (2017) Severe oxidative stress in an acute inflammatory demyelinating model in the rhesus monkey PlosOne, 12 (11): e0188013
  • Wiggermann V, Hametner S, Hernández-Torres E, Kames C, Endmayr V, Kasprian G, Höftberger R, Li D, Traboulsee A, Rauscher A (2017) Susceptibility-sensitive MRI of multiple sclerosis lesions and the impact of normal-appearing white matter changes NMR Biomed, 30 (8): e3727
  • Dal-Bianco A, Grabner G, Kronnerwetter C, Weber M, Höftberger R, Berger T, Auff E, Leutmezer F, Trattnig S, Lassmann H, Bagnato F, Hametner S (2017) Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging Acta Neuropathol, 133 (1): 25-42
  • Petersen M, Ryu J, Chang K, Etxeberria A, Bardehle S, Mendiola A, Kamau-Devers W, Fancy S, Thor A, Bushong E, Baeza-Raja B, Syme C, Wu M, Rios Coronado P, Meyer-Franke A, Yahn S, Pous L, Lee J, Schachtrup C, Lassmann H, Huang E, Han M, Absinta M, Reich D, Ellisman M, Rowitch D, Chan J, Akassoglou K (2017) Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage Neuron, 96(5): 1003-1012
  • Peschl P, Schanda K, Zeka B, Given K, Böhm D, Ruprecht K, Saiz A, Lutterotti A, Rostásy K, Höftberger R, Berger T, Macklin W, Lassmann H, Bradl M, Bennett J, Reindl M (2017) Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination J Neuroinflammation, 14 (1): 208
  • Tröscher A, Klang A, French M, Quemada-Garrido L, Kneissl S, Bien C, Pákozdy A, Bauer J (2017) Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies Front Immunol, 8: 1364
  • Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O’Loughlin E, Xu Y, Fanek Z, Greco D, Smith S, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich J, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner F, Litvak V, Holtzman D, Lassmann H, Weiner H, Ochando J, Haass C, Butovsky O (2017) The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases Immunity, 47 (3): 566-581.e9
  • Gabriely G, da Cunha A, Rezende R, Kenyon B, Madi A, Vandeventer T, Skillin N, Rubino S, Garo L, Mazzola M, Kolypetri P, Lanser A, Moreira T, Faria A, Lassmann H, Kuchroo V, Murugaiyan G, Weiner H (2017) Targeting latency-associated peptide promotes antitumor immunity Sci Immunol, 2 (11): eaaj1738
  • Kitic M, Karram K, Israel N, Yogev N, Lacher S, Tang Y, Yigit H, Bauer J, Wanke F, Knezovic A, Trotter J, Kurschus F, Waisman A (2017) NG2 plays a role in neuroinflammation but is not expressed by immune cells Acta Neuropathol, 134 (2): 325-327
  • Popkirov S, Ayzenberg I, Hahn S, Bauer J, Denno Y, Rieckhoff N, Radzimski C, Hans V, Berg S, Roghmann F, Noldus J, Bien C, Skodda S, Wellmer J, Stöcker W, Krogias C, Gold R, Schlegel U, Probst C, Komorowski L, Miske R, Kleiter I (2017) Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis Acta Neuropathologica Communications, 5 (1)
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  • Lemke A, Penzenstadler C, Ferguson J, Lidinsky D, Hopf R, Bradl M, Redl H, Wolbank S, Hausner T (2017) A novel experimental rat model of peripheral nerve scarring: reliably mimicking post-surgical complications and recurring adhesions Dis Model Mech, 10(8): 1015-1025
  • Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner H, Lassmann H (2017) Loss of ‘homeostatic’ microglia and patterns of their activation in active multiple sclerosis Brain, 140 (7): 1900-1913
  • Dunham J, Bauer J, Campbell G, Mahad D, van Driel N, van der Pol S, ‘t Hart B, Lassmann H, Laman J, van Horssen J, Kap Y (2017) Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis J Neuropath Exp Neurol, 76(6): 467-478
  • Karamita M, Barnum C, Möbius W, Tansey M, Szymkowski D, Lassmann H, Probert L (2017) Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia JCI Inside, 2 (8): e87455
  • Körtvélyessy P, Breu M, Pawlitzki M, Metz I, Heinze H, Matzke M, Mawrin C, Rommer P, Kovacs G, Mitter C, Reindl M, Brück W, Wandinger K, Lassmann H, Höftberger R, Leypoldt F (2017) ADEM-like presentation, anti-MOG antibodies, and MS pathology: TWO case reports Neurol Neuroimmunol Neuroinfl, 4 (3): e335
  • Popescu B, Frischer J, Webb S, Tham M, Adiele R, Robinson C, Fitz-Gibbon P, Weigand S, Metz I, Nehzati S, George G, Pickering I, Brück W, Hametner S, Lassmann H, Parisi J, Yong G, Lucchinetti C (2017) Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions Acta Neuropathol, 134 (1): 45-64
  • Espitia Pinzon N, Sanz-Morello B, Brevé J, Bol J, Drukarch B, Bauer J, Baron W, van Dam A (2017) Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination Sci Rep, 7: 40995
  • Laukoter S, Rauschka H, Tröscher A, Köck U, Saji E, Jellinger K, Lassmann H, Bauer J (2017) Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis Acta Neuropathol, 133(4): 613-627
  • Michailidou I, Naessens D, Hametner S, Guldenaar W, Kooi E, Geurts J, Baas F, Lassmann H, Ramaglia V (2017) Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis Glia, 65(2): 264-277

2017 Reviews

  • Lassmann H (2017) Targets of therapy in progressive MS Mult Scler, 23 (12): 1593-1599
  • ’t Hart B, Dunham J, Faber B, Laman J, van Horssen J, Bauer J, Kap Y (2017) A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model Front Immunol, 8: 804-
  • Bauer J, Becker A, Elyaman W, Peltola J, Rüegg S, Titulaer M, Varley J, Beghi E (2017) Innate and adaptive immunity in human epilepsies Epilepsia, 58: 57-68
  • Peschl P, Bradl M, Höftberger R, Berger T, Reindl M (2017) Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases Front Immunol, 8: 529
  • Türkoğlu R, Lassmann H, Aker F, Tzartos J, Tzartos S, Tüzün E (2017) Recurrent tumefactive demyelinating lesions: a pathological study Clin Neuropathol, 36(4): 195-198
  • Zeka B., Lassmann H., Bradl M. (2017) Müller cells and retinal axons can be primary targets in experimental neuromyelitis optica spectrum disorder Clinical and Experimental Neuroimmunology, 8: 3-7
  • Kuhlmann T, Ludwin S, Prat A, Antel J, Brück W, Lassmann H. (2017) An updated histological classification system for multiple sclerosis lesions Acta Neuropathol, 133(1): 13-24
  • Zurawski J, Lassmann H, Bakshi R. (2017) Use of Magnetic Resonance Imaging to Visualize Leptomeningeal Inflammation in Patients With Multiple Sclerosis: A Review. Jama Neurol, 74(1): 100-109
  • Lassmann H, Bradl M. (2017) Multiple sclerosis: experimental models and reality Acta Neuropathol, 133(2): 223-244
  • Kawachi I, Lassmann H (2017) Neurodegeneration in multiple sclerosis and neuromyelitis optica J Neurol Neurosurg Psychiatry, 88(2):: 137-145

2017 Book Chapters

  • Finsterer, J; Pakozdy, A; Bradl, M (2017) Epilepsy in Humans and Animals: From Patients to Disease Models. In: Jensen-Jarolim, E., Comparative Medicine: disorders linking humans with their animals Springer-Verlag : 13-25
  • Höftberger R, Lassmann H (2017) Immune-mediated disorders. In: , Handbook of Clinical Neurology : 285-299
  • Höftberger R, Lassmann H (2017) Inflammatory demyelinating diseases of the central nervous system. In: , Handbook of Clinical Neurology : 263-283

2016 Original Articles

  • Adzemovic M, Zeitelhofer M, Leisser M, Köck U, Kury A, Olsson T (2016) Immunohistochemical Analysis in the Rat Central Nervous System and Peripheral Lymph Node Tissue Sections J Vis Exp, (117)
  • Bernard-Valnet R, Yshii L, Quériault C, Nguyen X, Arthaud S, Rodrigues M, Canivet A, Morel A, Matthys A, Bauer J, Pignolet B, Dauvilliers Y, Peyron C, Liblau R (2016) CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice PNAS, 113 (39): 10956-10961
  • Yshii L, Gebauer C, Pignolet B, Mauré E, Quériault C, Pierau M, Saito H, Suzuki N, Brunner-Weinzierl M, Bauer J, Liblau R (2016) CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model Brain, 139 (11): 2923-2934
  • Peneder T, Bauer J, Pifl C (2016) Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice Movement Disorders, 31: 1729-1733
  • Burm S, Peferoen L, Zuiderwijk-Sick E, Haanstra K, ‘t Hart B, van der Valk P, Amor S, Bauer J, Bajramovic J (2016) Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself J Neuroinflammation, 13 (1)
  • Alidzanovic L, Starlinger P, Schauer D, Maier T, Feldman A, Buchberger E, Stift J, Koeck U, Pop L, Gruenberger B, Gruenberger T, Brostjan C (2016) The VEGF rise in blood of bevacizumab patients is not based on tumor escape but a host-blockade of VEGF clearance Oncotarget, 7(35): 57197-57212
  • Zeka B, Hastermann M, Kaufmann N, Schanda K, Pende M, Misu T, Rommer P, Fujihara K, Nakashima I, Dahle C, Leutmezer F, Reindl M, Lassmann H, Bradl M (2016) Aquaporin 4-specific T cells and NMO-IgG cause primary retinal damage in experimental NMO/SD Acta Neuropathologica Communications, 4 (1): 82
  • Wiedermann U, Sitte HH, Burgmann H, Eser A, Falb P, Holzmann H, Kitchen M, Köller M, Kollaritsch H, Kundi M, Lassmann H, Mutz I, Pickl WF, Riedl E, Sibilia M, Thalhammer F, Tucek B, Zenz W, Zwiauer K. (2016) Guidelines for vaccination of immunocompromised individuals Wiener Klinische Wochenschrift, 128 (S4): 337-376
  • Allan D, Fairlie-Clarke K, Elliott C, Schuh C, Barnett S, Lassmann H, Linnington C, Jiang H (2016) Role of IL-33 and ST2 signalling pathway in multiple sclerosis: expression by oligodendrocytes and inhibition of myelination in central nervous system Acta Neuropathologica Communications, 4 (1): 75
  • Schuh E, Berer K, Mulazzani M, Feil K, Meinl I, Lahm H, Krane M, Lange R, Pfannes K, Subklewe M, Gurkov R, Bradl M, Hohlfeld R, Kumpfel T, Meinl E, Krumbholz M (2016) Features of Human CD3+CD20+ T Cells J Immunol, 197 (4): 1111-1117
  • Mayo L, Cunha AP, Madi A, Beynon V, Yang Z, Alvarez JI, Prat A, Sobel RA, Kobzik L, Lassmann H, Quintana FJ, Weiner HL (2016) IL-10-dependent Tr1 cells attenuate astrocyte activation and ameliorate chronic central nervous system inflammation Brain, 139 (7): 1939-1957
  • Blaabjerg M, Ruprecht K, Sinnecker T, Kondziella D, Niendorf T, Kerrn-Jespersen B, Lindelof M, Lassmann H, Kristensen B, Paul F, Illes Z (2016) Widespread inflammation in CLIPPERS syndrome indicated by autopsy and ultra-high-field 7T MRI Neurol Neuroimmunol Neuroinflamm, 3 (3): e226-e226
  • Ramadan A, Lucca L, Carrié N, Desbois S, Axisa P, Hayder M, Bauer J, Liblau R, Mars L (2016) In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS Brain, : aww032
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  • Oji S, Nicolussi E, Kaufmann N, Zeka B, Schanda K, Fujihara K, Illes Z, Dahle C, Reindl M, Lassmann H, Bradl M (2016) Experimental Neuromyelitis Optica Induces a Type I Interferon Signature in the Spinal Cord PLoS One, 11 (3): e0151244
  • Haider L, Zrzavy T, Hametner S, Höftberger R, Bagnato F, Grabner G, Trattnig S, Pfeifenbring S, Brück W, Lassmann H (2016) The topograpy of demyelination and neurodegeneration in the multiple sclerosis brain Brain, 139 (3): 807-815
  • Dunham J, Lee L, van Driel N, Laman J, Ni I, Zhai W, Tu G, Lin J, Bauer J, ‘t Hart B, Kap Y (2016) Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis J Neuroimmune Pharmacol, 11 (1): 73-83

2016 Reviews

  • Lassmann H (2016) Demyelination and Neurodegeneration in Multiple Sclerosis: The Role of Hypoxia Ann Neurol, 79 (4): 520-521
  • Valent P, Groner B, Schumacher U, Superti-Furga G, Busslinger M, Kralovics R, Zielinski C, Penninger J, Kerjaschki D, Stingl G, Smolen J, Valenta R, Lassmann H, Kovar H, Jäger U, Kornek G, Müller M, Sörgel F (2016) Paul Ehrlich (1854-1915) and His Contributions to the Foundation and Birth of Translational Medicine J Innate Immun, 8(2): 111-120
  • Martin-Blondel G, Brassat D, Bauer J, Lassmann H, Liblau R (2016) CCR5 blockade for neuroinflammatory diseases — beyond control of HIV Nat Rev Neurol, 12(2): 95-105
  • Lassmann H, van Horssen J. (2016) Oxidative stress and its impact on neurons and glia in multiple sclerosis lesions Biochim Biophys Acta, 1862(3): 506-510
  • Bauer J, Lassmann H. (2016) Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis Methods Mol Biol, 1304: 211-229

2016 Book Chapters

  • Bauer J, Bien C (2016) Neuropathology of autoimmune encephalitides. In: , Handbook of Clinical Neurology : 107-120
  • Bradl M, Lassmann H (2016) Neurologic autoimmunity mechanisms revealed by animal models. In: , Handbook of Clinical Neurology : 121-143

2015 Original Articles

  • Zeka B, Hastermann M, Hochmeister S, Kögl N, Kaufmann N, Schanda K, Mader S, Misu T, Rommer P, Fujihara K, Illes Z, Leutmezer F, Sato D, Nakashima I, Reindl M, Lassmann H, Bradl M (2015) Highly encephalitogenic aquaporin 4-specific T cells and NMO-IgG jointly orchestrate lesion location and tissue damage in the CNS Acta Neuropathol, 130 (6): 783-798
  • Aboulenein-Djamshidian F, Höftberger R, Waters P, Krampla W, Lassmann H, Budka H, Vincent A, Kristoferitsch W (2015) Reduction in Serum Aquaporin-4 Antibody Titers During Development of a Tumor-Like Brain Lesion in a Patient With Neuromyelitis Optica: A Serum Antibody–Consuming Effect? J Neuropath Exp Neurol, 74 (3): 194-197
  • Dal-Bianco A, Hametner S, Grabner G, Schernthaner M, Kronnerwetter C, Reitner A, Vass C, Kircher K, Auff E, Leutmezer F, Vass K, Trattnig S (2015) Veins in plaques of multiple sclerosis patients – a longitudinal magnetic resonance imaging study at 7 Tesla – Eur Radiol, 25 (10): 2913-2920
  • Jagessar S, Heijmans N, Blezer E, Bauer J, Weissert R, ‘t Hart B (2015) Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant J Neuroinflammation, 12 (1): 169
  • Höftberger R, Leisser M, Bauer J, Lassmann H (2015) Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ? Acta Neuropathologica Communications, 3 (1): 80
  • Di Pauli F, Hoftberger R, Reindl M, Beer R, Rhomberg P, Schanda K, Sato D, Fujihara K, Lassmann H, Schmutzhard E, Berger T (2015) Fulminant demyelinating encephalomyelitis: Insights from antibody studies and neuropathology Neurol Neuroimmunol Neuroinflamm, 2 (6): e175-e175
  • Hernández-Torres E, Wiggermann V, Hametner S, Baumeister T, Sadovnick A, Zhao Y, Machan L, Li D, Traboulsee A, Rauscher A (2015) Orientation Dependent MR Signal Decay Differentiates between People with MS, Their Asymptomatic Siblings and Unrelated Healthy Controls PLoS One, 10 (10): e0140956
  • Ryu JK, Petersen MA, Murray SG, Baeten KM, Meyer-Franke A, Chan JP, Vagena E, Bedard C, Machado MR, Coronado PE, Prod'homme T, Charo IF, Lassmann H, Degen JL, Zamvil SS, Akassoglou K (2015) Blood coagulation protein fibrinogen promotes autoimmunity and demyelination via chemokine release and antigen presentation Nat Commun, 6: 8164
  • Kortvelyessy P, Bauer J, Stoppel C, Bruck W, Gerth I, Vielhaber S, Wiedemann F, Heinze H, Bartels C, Bien C (2015) Complement-associated neuronal loss in a patient with CASPR2 antibody-associated encephalitis Neurol Neuroimmunol Neuroinflamm, 2 (2): e75-e75. PK and JB share first authorship
  • Haanstra K, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart B, Vanhove B (2015) Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis J Immunol, 194 (4): 1454-1466
  • Frischer J, Weigand S, Guo Y, Kale N, Parisi J, Pirko I, Mandrekar J, Bramow S, Metz I, Brück W, Lassmann H, Lucchinetti C (2015) Clinical and pathological insights into the dynamic nature of the white matter multiple sclerosis plaque Ann Neurol, 78(5): 710-721
  • Licht-Mayer S, Wimmer I, Traffehn S, Metz I, Brück W, Bauer J, Bradl M, Lassmann H. (2015) Cell type-specific Nrf2 expression in multiple sclerosis lesions Acta Neuropathol, 130 (2): 263-277
  • Kaushansky N, Eisenstein M, Boura-Halfon S, Hansen BE, Nielsen CH, Milo R, Zeilig G, Lassmann H, Altmann DM, Ben-Nun A. (2015) Role of a novel HLA-DQA1*01:02;DRB1*15:01 mixed-isotype heterodimer in the pathogenesis of 'humanized' multiple sclerosis-like disease J Biol Chem, 290 (24): 15260-15278
  • Lindner M, Thümmler K, Arthur A, Brunner S, Elliott C, McElroy D, Mohan H, Williams A, Edgar JM, Schuh C, Stadelmann C, Barnett SC, Lassmann H, Mücklisch S, Mudaliar M, Schaeren-Wiemers N, Meinl E, Linington C (2015) Fibroblast growth factor signalling in multiple sclerosis: inhibition of myelination and induction of pro-inflammatory environment by FGF9 Brain, 138 (7): 1875-1893
  • Bagnato F, Hametner S, Pennell D, Dortch R, Dula A, Pawate S, Smith S, Lassmann H, Gore J, Welch E (2015) 7T MRI-Histologic Correlation Study of Low Specific Absorption Rate T2-Weighted GRASE Sequences in the Detection of White Matter Involvement in Multiple Sclerosis J Neuroimaging, 25 (3): 370-378
  • Spadaro M, Gerdes LA, Mayer MC, Ertl-Wagner B, Laurent S, Krumbholz M, Breithaupt C, Högen T, Straube A, Giese A, Hohlfeld R, Lassmann H, Meinl E, Kümpfel T. (2015) Histopathology and clinical course of MOG-antibody-associated encephalomyelitis Ann Clin Transl Neurol, 2(3: 295-301
  • Martin-Blondel G, Bauer J, Uro-Coste E, Biotti D, Averseng-Peaureaux D, Fabre N, Dumas H, Bonneville F, Lassmann H, Marchou B, Liblau RS, Brassat D. (2015) Therapeutic use of CCR5 antagonists is supported by strong expression of CCR5 on CD8+ T cells in progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome Acta Neuropathol, 129(3): 463-465
  • Tseveleki V, Tselios T, Kanistras I, Koutsoni O, Karamita M, Vamvakas S, Apostolopoulos V, Dotsika E, Matsoukas J, Lassmann H, Probert L (2015) Mannan-conjugated myelin peptides prime non-pathogenic Th1 and Th17 cells and ameliorate experimental autoimmune encephalomyelitis Exp. Neurol., 267: 254-267
  • Butovsky O, Jedrychowski M, Cialic R, Krasemann S, Murugaiyan G, Fanek Z, Greco D, Wu P, Doykan C, Kiner O, Lawson R, Frosch M, Pochet N, Fatimy R, Krichevsky A, Gygi S, Lassmann H, Berry J, Cudkowicz M, Weiner H (2015) Targeting miR-155 restores abnormal microglia and attenuates disease in SOD1 mice Ann Neurol, 77(1): 75-99
  • Skliris A, Papadaki O, Kafasla P, Karakasiliotis I, Hazapis O, Reczko M, Grammenoudi S, Bauer J, Kontoyiannis D (2015) Neuroprotection requires the functions of the RNA-binding protein HuR Cell Death Differ, 22(5): 703-718
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2015 Reviews

  • Lassmann H (2015) Spinal cord pathology in multiple sclerosis Lancet Neurol, 14 (4): 348-349
  • Bauer J, Gold R, Adams O, Lassmann H. (2015) Progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome (IRIS) Acta Neuropathol, 130(6): 751-764
  • Haider L (2015) Inflammation, Iron, Energy Failure, and Oxidative Stress in the Pathogenesis of Multiple Sclerosis Oxid Med Cell Longev, 2015: 1-10
  • Mahad DH, Trapp BD, Lassmann H (2015) Pathological mechanisms in progressive multiple sclerosis Lancet Neurology, 14: 183–93
  • Weier K, Banwell B, Cerasa A, Collins DL, Dogonowski AM, Lassmann H, Quattrone A, Sahraian MA, Siebner HR, Sprenger T. (2015) The Role of the Cerebellum in Multiple Sclerosis Cerebellum, 14(3): 364-74

2015 Book Chapters

  • Lassmann H (2015) Immune Response in the Human Central Nervous System in Multiple Sclerosis and Stroke. In: Wiley-Blackwell, Neuroinflammation - New Insights into Beneficial and Detrimental Functions Wiley-Blackwell: 3-19

2014 Original Articles

  • Mohan H, Friese A, Albrecht S, Krumbholz M, Elliott CL, Arthur A, Menon R, Farina C, Junker A, Stadelmann C, Barnett SC, Huitinga I, Wekerle H, Hohlfeld R, Lassmann H, Kuhlmann T, Linington C, Meinl E. (2014) Transcript profiling of different types of multiple sclerosis lesions yields FGF1 as a promoter of remyelination Acta Neuropathologica Communications, 2(1): 178
  • Hochmeister S, Pekar T, Lindner M, Kitic M, Haindl M, Storch M, Fazekas F, Linington C (2014) Maternal Neurofascin-Specific Autoantibodies Bind to Structures of the Fetal Nervous System during Pregnancy, but Have No Long Term Effect on Development in the Rat PLoS One, 9 (1): e85393
  • Nijland PG, Witte ME, van Het Hof B, van der Pol S, Bauer J, Lassmann H, van der Valk P, de Vries HE, van Horssen J. (2014) Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis Acta Neuropathologica Communications, 2(1): 170
  • Yao B, Hametner S, van Gelderen P, Merkle H, Chen C, Lassmann H, Duyn J, Bagnato F (2014) 7 Tesla Magnetic Resonance Imaging to Detect Cortical Pathology in Multiple Sclerosis PLoS One, 9 (10): e108863
  • Marlatt M, Bauer J, Aronica E, van Haastert E, Hoozemans J, Joels M, Lucassen P (2014) Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition Neural Plast, 2014: 1-12
  • Espitia Pinzon N, Stroo E, ‘t Hart B, Bol J, Drukarch B, Bauer J*, van Dam A* (2014) Tissue Transglutaminase in Marmoset Experimental Multiple Sclerosis: Discrepancy between White and Grey Matter PLoS One, 9 (6): e100574. *JB and AvD share senior authorship
  • Castelo-Branco G, Stridh P, Guerreiro-Cacais A, Adzemovic M, Falcão A, Marta M, Berglund R, Gillett A, Hamza K, Lassmann H, Hermanson O, Jagodic M (2014) Acute treatment with valproic acid and l-thyroxine ameliorates clinical signs of experimental autoimmune encephalomyelitis and prevents brain pathology in DA rats Neurobiol Dis, 71: 220-233
  • Taieb G, Uro-Coste E, Clanet M, Lassmann H, Benouaich-Amiel A, Laurent C, Delisle M, Labauge P, Brassat D (2014) A central nervous system B-cell lymphoma arising two years after initial diagnosis of CLIPPERS J Neurol Sci, 344 (1-2): 224-226
  • Guo Y, Lennon VA, Popescu BF, Grouse CK, Topel J, Milone M, Lassmann H, Parisi JE, Pittock SJ, Stefoski D, Balabanov R, Lucchinetti CF (2014) Autoimmune Aquaporin-4 Myopathy in Neuromyelitis Optica Spectrum Jama Neurol, 71 (8): 1025
  • Haider L, Simeonidou C, Steinberger G, Hametner S, Grigoriadis N, Deretzi G, Kovacs G, Kutzelnigg A, Lassmann H, Frischer J (2014) Multiple sclerosis deep grey matter: the relation between demyelination, neurodegeneration, inflammation and iron J Neurol Neurosurg Psychiatry, 85(12): 1386-1395
  • Metz Imke, Weigand Stephen D, Popescu Bogdan F.G., Frischer Josa M, Parisi Joseph E, Guo Yong, Lassmann Hans, Brück Wolfgang, Lucchinetti Claudia F. (2014) Pathologic heterogeneity persists in early active multiple sclerosis lesions Ann Neurol, 75 (5): 728-738
  • Mars Lennart T., Mas Magali, Beaudoin Lucie, Bauer Jan, Leite-de-Moraes Maria, Lehuen Agnès, Bureau Jean-Francois, Liblau Roland S. (2014) Invariant NKT Cells Regulate the CD8 T Cell Response during Theiler's Virus Infection PLoS.ONE., 9 (1): e87717
  • Klang Andrea, Schmidt Peter, Kneissl Sibylle, Bagó Zoltán, Vincent Angela, Lang Bethan, Moloney Teresa, Bien Christian G., Halász Péter, Bauer Jan*, Pákozdy Ákos* (2014) IgG and Complement Deposition and Neuronal Loss in Cats and Humans With Epilepsy and Voltage-Gated Potassium Channel Complex Antibodies J Neuropath Exp Neurol, 73 (5): 403-413. *JB and AP share senior authorship
  • Kitic Maja, Wimmer Isabella, Adzemovic Milena, Kögl Nikolaus, Rudel Antonia, Lassmann Hans, Bradl Monika (2014) Thymic stromal lymphopoietin is expressed in the intact central nervous system and upregulated in the myelin-degenerative central nervous system Glia, 62 (7): 1066-1074
  • Schuh C, Wimmer I, Hametner S, Haider L, Van Dam AM, Liblau RS, Smith KJ, Probert L, Binder CJ, Bauer J, Bradl M, Mahad D, Lassmann H. (2014) Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models Acta Neuropathol, 128 (2): 247-266
  • Frischer J, Reindl M, Künz B, Berger T, Schmidt S, Milford E, Knosp E, Lassmann H, Utku N. (2014) TIRC7 and HLA-DR axis contributes to inflammation in multiple sclerosis Mult Scler, 20(9) : 1171 –1181
  • Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, Zezula J, Weissmann S, Xie Y, Schöfer C, Schlederer M, Brosch G, Matthias P, Selfridge J, Lassmann H, Knoblich JA, Seiser C. (2014) A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog Development, 141(3): 604-616
  • Grabner G, Dal-Bianco A, Hametner S, Lassmann H, Trattnig S. (2014) Group specific vein-atlasing: An application for analyzing the venous system under normal and multiple sclerosis conditions J Magn Reson Imaging, 40 (3): 655-661

2014 Reviews

  • Lassmann H (2014) CNS neuroimmunology seen by a neuropathologist Rev Neurol (Paris), 170(10): 561-563
  • Lassmann H (2014) Genetic Control of Nerve Conduction Velocity May Influence Multiple Sclerosis Phenotype Am.J.Pathol., 184 (9): 2369-2370
  • Bradl M, Kanamori Y, Nakashima I, Misu T, Fujihara K, Lassmann H, Sandkühler J. (2014) Pain in neuromyelitis optica-prevalence, pathogenesis and therapy Nat Rev Neurol, 10 (9): 529-536
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  • Filippi M, Rocca M, Lassmann H (2014) KIR4.1: another misleading expectation in multiple sclerosis? Lancet Neurol, 13(8): 753-755
  • Bien C, Bauer J (2014) Autoimmune Epilepsies Neurotherapeutics, 11 (2): 311-318
  • Varadkar Sophia, Bien Christian G, Kruse Carol A, Jensen Frances E, Bauer Jan, Pardo Carlos A, Vincent Angela, Mathern Gary W, Cross J Helen (2014) Rasmussen's encephalitis: clinical features, pathobiology, and treatment advances Lancet Neurology, 13 (2): 195-205
  • Lassmann H (2014) Mechanisms of white matter damage in multiple sclerosis Glia, 62(11): 1816-1830
  • Bradl M, Lassmann H (2014) Experimental models of neuromyelitis optica Brain Pathol, : 24(1):74-82
  • Witte ME, Mahad DJ, Lassmann H, van Horssen J. (2014) Mitochondrial dysfunction contributes to neurodegeneration in multiple sclerosis Trends Mol Med, 20(3): 179-187

2014 Book Chapters

  • Bauer J, Lang B, Irani S, Vezzani A (2014) Immune Responses in the CNS in Epilepsy. In: Nicola Woodroofe and Sandra Amor, Neuroinflammation and CNS Disorders John Wiley & Sons, Ltd: 289-315
  • Kutzelnigg A, Lassmann H. (2014) Pathology of multiple sclerosis and related inflammatory demyelinating diseases. In: , Handbook of Clinical Neurology : 15-58

2013 Original Articles

  • Haanstra KG, Jagessar SA, Bauchet AL, Doussau M, Fovet CM, Heijmans N, Hofman SO, van Lubeek-Veth J, Bajramovic JJ, Kap YS, Laman JD, Touin H, Watroba L, Bauer J, Lachapelle F, Serguera C, 't Hart BA (2013) Induction of experimental autoimmune encephalomyelitis with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant in three non-human primate species J Neuroimmune Pharmacol, 8(5): 1251-1264
  • Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer MT, Machado-Santos J, Mader S, Ellwart JW, Misu T, Fujihara K, Wekerle H, Reindl M, Lassmann H, Bradl M (2013) T cell-activation in neuromyelitis optica lesions plays a role in their formation Acta Neuropathologica Communications, : 1(1):85
  • Dauvilliers Y, Bauer J, Rigau V, Lalloyer N, Labauge P, Carlander B, Liblau R, Peyron C, Lassmann H. (2013) Hypothalamic Immunopathology in Anti-Ma-Associated Diencephalitis With Narcolepsy-Cataplexy Jama Neurol, 70(10): 1305-1310
  • Martin-Blondel G, Bauer J, Cuvinciuc V, Uro-Coste E, Debard A, Massip P, Delisle MB, Lassmann H, Marchou B, Mars LT, Liblau RS (2013) In situ evidence of JC virus control by CD8+ T cells in PML-IRIS during HIV infection Neurology, 81(11): 964-970
  • Hametner S, Wimmer I, Haider L, Pfeifenbring S, Brück W, Lassmann H. (2013) Iron and Neurodegeneration in the Multiple Sclerosis Brain Ann Neurol, 74: 848–861
  • Fischer MT, Wimmer I, Höftberger R, Gerlach S, Haider L, Zrzavy T, Hametner S, Mahad D, Binder CJ, Krumbholz M, Bauer J, Bradl M, Lassmann H. (2013) Disease-specific molecular events in cortical multiple sclerosis lesions Brain, 136(Pt 6): 1799-1815
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  • Kitic M, Hochmeister S, Wimmer I, Bauer J, Misu T, Mader S, Reindl M, Fujihara K, Lassmann H, Bradl M (2013) Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats Acta Neuropathologica Communications, 1(1) : 5
  • Misu T, Höftberger R, Fujihara K, Wimmer I, Takai Y, Nishiyama S, Nakashima I, Konno H, Bradl M, Garzuly F, Itoyama Y, Aoki M, Lassmann H (2013) Presence of six different lesion types suggests diverse mechanisms of tissue injury in neuromyelitis optica Acta Neuropathol, 125(6): 815-827
  • Haanstra KG, Hofman SO, Lopes Estêvão DM, Blezer EL, Bauer J, Yang LL, Wyant T, Csizmadia V, 't Hart BA, Fedyk ER (2013) Antagonizing the a4b1 integrin, but not a4b7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis J Immunol, 190(5): 1961-1973
  • Jagessar SA, Fagrouch Z, Heijmans N, Bauer J, Laman JD, Oh L, Migone T, Verschoor EJ, 't Hart BA. (2013) The Different Clinical Effects of Anti-BLyS, Anti-APRIL and Anti-CD20 Antibodies Point at a Critical Pathogenic Role of -Herpesvirus Infected B Cells in the Marmoset EAE Model J Neuroimmune Pharmacol, 8(3): 727-738
  • Pakozdy A, Halasz P, Klang A, Bauer J, Leschnik M, Tichy A, Thalhammer JG, Lang B, Vincent A. (2013) Suspected Limbic Encephalitis and Seizure in Cats Associated with Voltage-Gated Potassium Channel (VGKC) Complex Antibody J Vet Intern Med, 27(1): 212-214
  • Berghoff AS, Lassmann H, Preusser M, Höftberger R. (2013) Characterization of the inflammatory response to solid cancer metastases in the human brain Clin Exp Metastasis, 30(1): 69-81
  • Filippi M, Preziosa P, Pagani E, Copetti M, Mesaros S, Colombo B, Horsfield M, Falini A, Comi G, Lassmann H, Rocca M. (2013) Microstructural magnetic resonance imaging of cortical lesions in multiple sclerosis Mult Scler, 19(4): 418-426

2013 Reviews

  • Lassmann H (2013) Multiple sclerosis: Lessons from molecular neuropathology Exp. Neurol., 262 Pt A: 2-7
  • Lassmann H (2013) Pathology and disease mechanisms in different stages of multiple sclerosis J Neurol Sci, 333 (1-2): 1-4
  • Bien CG, Bauer J (2013) Pathophysiologie antikörperassoziierter ZNS-Erkrankungen Nervenarzt, 84: 466–470
  • Filippi M, Rocca MA, Horsfield MA, Hametner S, Geurts JJ, Comi G, Lassmann H. (2013) Imaging Cortical Damage and Dysfunction in Multiple Sclerosis Jama Neurol, 70(5): 556-564
  • Lassmann H (2013) Relapsing-remitting and primary progressive MS have the same cause(s) - the neuropathologist's view: 1 Mult Scler, Mar;19(3): 266-267
  • Bagnato F, Hametner S, Welch EB (2013) Visualizing iron in multiple sclerosis Magn Reson Imaging, 31(3): 376-384
  • Lassmann H (2013) Henry de Forest Webster (1927-2012) Acta Neuropathol, 125(2): 311-312

2012 Original Articles

  • Jagessar SA, Heijmans N, Bauer J, Blezer EL, Laman JD, Migone TS, Devalaraja MN, 't Hart BA. (2012) Antibodies against human BLyS and APRIL attenuate EAE development in marmoset monkeys J Neuroimmune Pharmacol, 7(3): 557-570
  • Jagessar SA, Heijmans N, Bauer J, Blezer EL, Laman JD, Hellings N, 't Hart BA. (2012) B-cell depletion abrogates T cell-mediated demyelination in an antibody-nondependent common marmoset experimental autoimmune encephalomyelitis model J Neuropath Exp Neurol, 71(8): 716-728
  • Hochmeister S, Romauch M, Bauer J, Seifert-Held t, Weissert R, Linington C, Hartung HP, Fazekas F, Storch MK (2012) Re-expression of N-cadherin in remyelinating lesions of experimental inflammatory demyelination Exp. Neurol., 237: 70-77
  • Davalos D, Ryu JK, Merlini M, Baeten KM, Le Moan N, Petersen MA, Deerinck TJ, Smirnoff DS, Bedard C, Hakozaki H, Gonias Murray S, Ling JB, Lassmann H, Degen JL, Ellisman MH, Akassoglou K. (2012) Fibrinogen-induced perivascular microglial clustering is required for the development of axonal damage in neuroinflammation Nat Commun, 3: 1227
  • Rigau V, Mania A, Béfort P, Carlander B, Jonquet O, Lassmann H, Camu W, Thouvenot E. (2012) Lethal Multiple Sclerosis Relapse after Natalizumab withdrawal Neurology, 79(22): 2214-2216
  • Maj M, Milenkovic I, Bauer J, Berggard T, Veit M, Ilhan-Mutlu A, Wagner L, Tretter V (2012) Novel insights into the distribution and functional aspects of the calcium binding protein Secretagogin from studies on rat brain and primary neuronal cell culture Front Mol Neurosci, 5: Article 84
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  • Adzemovic MZ, Ockinger J, Zeitelhofer M, Hochmeister S, Beyeen AD, Paulson A, Gillett A, Hedreul MT, Covacu R, Lassmann H, Olsson T, Jagodic M. (2012) Expression of Ccl11 Associates with Immune Response Modulation and Protection against Neuroinflammation in Rats PLoS.ONE., : 7(7):e39794
  • Campbell GR, Kraytsberg Y, Krishnan KJ, Ohno N, Ziabreva I, Reeve A, Trapp BD, Newcombe J, Reynolds R, Lassmann H, Khrapko K, Turnbull DM, Mahad DJ. (2012) Clonally expanded mitochondrial DNA deletions within the choroid plexus in multiple sclerosis Acta Neuropathol, 124(2): 209-220
  • Preusser M, Hassler M, Birner P, Rudas M, Acker T, Plate H, Widhalm G, Knosp E, Breitschopf H, Berger J, Marosi C. (2012) Microvascularization and expression of VEGF and its receptors in recurring meningiomas: pathobiological data in favor of anti-angiogenic therapy approaches Clin Neuropathol, 31(5): 352-360
  • Bien CG, Vincent A, Barnett MH, Becker AJ, Blümcke I, Graus F, Jellinger KA, Reuss DE, Ribalta T, Schlegel J, Sutton I, Lassmann H, Bauer J. (2012) Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis Brain, 135(Pt 5): 1622-1638
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  • Scheikl T, Pignolet B, Dalard C, Desbois S, Raison D, Yamazaki M, Saoudi A, Bauer J, Lassmann H, Hardin-Pouzet H, Liblau RS. (2012) Cutting Edge: Neuronal Recognition by CD8 T Cells Elicits Central Diabetes Insipidus J Immunol, 188 (10): 4731-4735
  • Lax NZ, Campbell GR, Reeve AK, Ohno N, Zambonin J, Blakely EL, Taylor RW, Bonilla E, Tanji K, Dimauro S, Jaros E, Lassmann H, Turnbull DM, Mahad DJ. (2012) Loss of myelin-associated glycoprotein in kearns-sayre syndrome Arch Neurol, 69(4): 490-499.
  • Kaushansky N, Altmann DM, David CS, Lassmann H, Ben-Nun A. (2012) DQB1*0602 rather than DRB1*1501 confers susceptibility to multiple sclerosis-like disease induced by proteolipid protein (PLP). J Neuroinflammation, 9(1): 29
  • Jagessar SA, Heijmans N, Blezer EL, Bauer J, Blokhuis JH, Wubben JA, Drijfhout JW, van den Elsen PJ, Laman JD, Hart BA (2012) Unravelling the T-cell-mediated autoimmune attack on CNS myelin in a new primate EAE model induced with MOG(34-56) peptide in incomplete adjuvant Eur. J. Immunol., 42(1): 217-227
  • Jagessar SA, Gran B, Heijmans N, Bauer J, Laman JD, 't Hart BA, Constantinescu CS (2012) Discrepant Effects of Human Interferon-gamma on Clinical and Immunological Disease Parameters in a Novel Marmoset Model for Multiple Sclerosis J Neuroimmune Pharmacol, 7(1): 253-265
  • Fischer MT, Sharma R, Lim J, Haider L, Frischer J, Drexhage J, Mahad D, Bradl M, van Horssen J, Lassmann H (2012) NADPH Oxidase Expression in Active Multiple Sclerosis Lesions in Relation to Oxidative Tissue Damage and Mitochondrial Injury Brain, 135: 886-899
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  • Eisele S, Krumbholz M, Fischer M-T, Mohan H, Junker A, Arzberger T, Hohlfeld R, Bradl M, Lassmann H, Meinl E (2012) Prospects of transcript profiling for mRNAs and microRNAs using formalin fixed paraffin embedded dissected autoptic multiple sclerosis lesions Brain Pathol, 22(5): 607-618

2012 Reviews

  • Lassmann H (2012) Targeting intracerebral inflammation in multiple sclerosis: is it feasible? Acta Neuropathol, 124(3): 395-396
  • Berger T, Lassmann H (2012) Karl Vass, 1958-2012 Mult Scler, 18(12): 1666-1667
  • Fujihara K, Misu T, Nakashima I, Takahashi T, Bradl M, Lassmann H, Takano R, Nishiyama S, Takai Y, Suzuki C, Sato D, Kuroda H, Nakamura M, Fujimori J, Narikawa K, Sato S, Itoyama Y, Aoki M (2012) Neuromyelitis optica should be classified as an astrocytopathic disease rather than a demyelinating disease Clinical and Experimental Neuroimmunology, 3: 58-73
  • Lassmann H (2012) Cortical lesions in multiple sclerosis: inflammation versus neurodegeneration Brain, 135(Pt 10): 2904-2905
  • Lassmann H, van Horssen J, Mahad D (2012) Progressive multiple sclerosis: pathology and pathogenesis Nat Rev Neurol, 8(11): 647-656
  • Rathinam C, Lassmann H, Mengel M, Klein C. (2012) Retraction: transcription factor gfi1 restricts B cell-mediated autoimmunity J Immunol, : 189(7):3777
  • Lassmann H (2012) The birth of oligodendrocytes in the anatomical and neuropathological literature: the seminal contribution of Pío del Río-Hortega. Clin Neuropathol, 31(6): 435-436
  • Bauer J, Vezzani A, Bien CG (2012) Epileptic encephalitis: the role of the innate and adaptive immune system Brain Pathol, 22(3): 412-421
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  • Filippi M, Rocca MA, Barkhof F, Brück W, Chen JT, Comi G, Deluca G, De Stefano N, Erickson BJ, Evangelou N, Fazekas F, Geurts JJ, Lucchinetti C, Miller DH, Pelletier D, Popescu BF, Lassmann H (2012) Association between pathological and MRI findings in multiple sclerosis Lancet Neurology, 11(4): 349-360
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  • Bradl M, Lassmann H. (2012) Microarray analysis on archival multiple sclerosis tissue: Pathogenic authenticity outweighs technical obstacles Neuropathology, 32(4): 463-466

2012 Book Chapters

  • Bradl M and Lassmann H (2012) Multiple Sclerosis. In: Kettenmann H and Ransom B, Neuroglia, Third Edition Oxford University Press, Oxford New York: 785-797

2011 Original Articles

  • Kap YS, Bauer J, Driel N, Bleeker WK, Parren PW, Kooi EJ, Geurts JJ, Laman JD, Craigen JL, Blezer E, 't Hart BA (2011) B-cell depletion attenuates white and gray matter pathology in marmoset experimental autoimmune encephalomyelitis J Neuropath Exp Neurol, 70(11): 992-1005
  • Bagnato F, Hametner S, Yao B, van Gelderen P, Merkle H, Cantor FK, Lassmann H, Duyn JH. (2011) Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla Brain, 134(Pt 12): 3602-3615.
  • Lucchinetti CF, Popescu BFG, Bunyan RF, Moll NM, Roemer SF, Lassmann H, Brück W, Parisi JE, Scheithauer BW, Giannini C, Weigand SD, Mandrekar J, Ransohoff RM (2011) Inflammatory Cortical Demyelination in Early Multiple Sclerosis N Engl J Med, 365(23): 2188-2197.
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  • Taoufik E, Tseveleki V, Chu SY, Tselios T, Karin M, Lassmann H, Szymkowski DE, Probert L. (2011) Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-{kappa}B Brain, 134(Pt 9): 2722-2735
  • Van Strien ME, Baron W, Bakker EN, Bauer J, Bol JG, Brevé JJ, Binnekade R, Van Der Laarse WJ, Drukarch B, Van Dam AM (2011) Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin-forming oligodendrocytes during CNS remyelination Glia, 59(11): 1622-1634
  • Deckert M, Engert A, Brück W, Ferreri AJ, Finke J, Illerhaus G, Klapper W, Korfel A, Küppers R, Maarouf M, Montesinos-Rongen M, Paulus W, Schlegel U, Lassmann H, Wiestler OD, Siebert R, Deangelis LM. (2011) Modern concepts in the biology, diagnosis, differential diagnosis and treatment of primary central nervous system lymphoma Leukemia, 25(12): 1797-807.
  • Zambonin JL, Zhao C, Ohno N, Campbell GR, Engeham S, Ziabreva I, Schwarz N, Lee SE, Frischer JM, Turnbull DM, Trapp BD, Lassmann H, Franklin RJ, Mahad DJ. (2011) Increased mitochondrial content in remyelinated axons: implications for multiple sclerosis Brain, 134(Pt 7):: 1901-1913.
  • Haider L, Fischer MT, Frischer JM, Bauer J, Höftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL, Lassmann H. (2011) Oxidative damage in multiple sclerosis lesions Brain, 134(Pt 7):: 1914-1924
  • Serbecic N, Aboul-Enein F, Beutelspacher SC, Vass C, Kristoferitsch W, Lassmann H, Reitner A, Schmidt-Erfurth U. (2011) High Resolution Spectral Domain Optical Coherence Tomography (SD-OCT) in Multiple Sclerosis: The First Follow Up Study over Two Years PLoS.ONE., : 6(5):e19843
  • Grabner G, Dal-Bianco A, Schernthaner M, Vass K, Lassmann H, Trattnig S (2011) Analysis of multiple sclerosis lesions using a fusion of 3.0 T FLAIR and 7.0 T SWI phase: FLAIR SWI J Magn Reson Imaging, 33(3): 543-549
  • Lichtenbergová L, Lassmann H, Jones MK, Kolá&#345;ová L, Horák P (2011) Trichobilharzia regenti: Host immune response in the pathogenesis of neuroinfection in mice Exp Parasitol, 128(4): 328-335
  • Pohl M, Fischer MT, Mader S, Schanda K, Kitic M, Sharma R, Wimmer I, Misu T, Fujihara K, Reindl M, Lassmann H, Bradl M. (2011) Pathogenic T cell responses against aquaporin 4 Acta Neuropathol, 122(1): 21-34
  • Grigoriadis N, Lourbopoulos A, Lagoudaki R, Frischer JM, Polyzoidou E, Touloumi O, Simeonidou C, Deretzi G, Kountouras J, Spandou E, Kotta K, Karkavelas G, Tascos N, Lassmann H. (2011) Variable behavior of autologous bone marrow mesenchymal stem cells transplanted in experimental autoimmune encephalomyelitis Exp. Neurol., 230(1): 78-89
  • Serbecic N, Beutelspacher SC, Geitzenauer W, Kircher K, Lassmann H, Reitner A, Khan A, Schmidt-Erfurth U. (2011) RNFL thickness in MS-associated acute optic neuritis using SD-OCT: critical interpretation and limitations Acta Ophtalmol, 89(5): e451-460
  • Peneder TM, Scholze P, Berger ML, Reither H, Heinze G, Bertl J, Bauer J, Richfield EK, Hornykiewicz O, Pifl C (2011) Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice Neuroscience, 180: 280-292
  • Campbell GR, Ziabreva I, Reeve AK, Krishnan KJ, Reynolds R, Howell O, Lassmann H, Turnbull DM, Mahad DJ. (2011) Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis Ann Neurol, 69(3): 481-492

2011 Reviews

  • Lassmann H, van Horssen J. (2011) The molecular basis of neurodegeneration in multiple sclerosis FEBS Letters, 585(23): 3715-3723
  • Bien CG, Bauer J. (2011) Which pathomechanism damages the brain in antibody-associated CNS disease? Neurology, 77(5): 414-415
  • Lassmann H, Niedobitek G, Aloisi F, Middeldorp JM; the NeuroproMiSe EBV Working Group (2011) Epstein-Barr virus in the multiple sclerosis brain: a controversial issue--report on a focused workshop held in the Centre for Brain Research of the Medical University of Vienna, Austria Brain, 134(Pt 9) : 2772-2786
  • Lassmann H (2011) A dynamic view of the blood-brain barrier in active multiple sclerosis lesions Ann Neurol, 70(1): 1-2
  • Lassmann H (2011) The Architecture of Inflammatory Demyelinating Lesions: Implications for Studies on Pathogenesis Neuropathol Appl Neurobiol, 37(7): 698-710
  • Lassmann H, Bancher C, Attems J, Paulus W. (2011) In honor of the 80th birthday of Kurt Jellinger: a living legend in neuropathology Acta Neuropathol, 121(5): 565-568
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  • Lassmann H (2011) Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer's disease J Neural Transm, 118(5): 747-752
  • Lassmann H. (2011) Pathophysiology of inflammation and tissue injury in multiple sclerosis: What are the targets for therapy J Neurol Sci, 306(1-2): 167-169
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2010 Original Articles

  • Málaga-Diéguez L, Yang Q, Bauer J, Pankevych H, Freissmuth M, Nanoff C. (2010) Pharmacochaperoning of the A1 adenosine receptor is contingent on the endoplasmic reticulum Mol Pharmacol, 77(6): 940-952
  • Domingues HS, Mues M, Lassmann H, Wekerle H, Krishnamoorthy G. (2010) Functional and pathogenic differences of Th1 and th17 cells in experimental autoimmune encephalomyelitis PLoS.ONE., 5(11): e15531
  • Serbecic N, Aboul-Enein F, Beutelspacher SC, Graf M, Kircher K, Geitzenauer W, Brannath W, Lang P, Kristoferitsch W, Lassmann H, Reitner A, Schmidt-Erfurth U. (2010) Heterogeneous Pattern of Retinal Nerve Fiber Layer in Multiple Sclerosis. High Resolution Optical Coherence Tomography: Potential and Limitations PLoS.ONE., 5(11): e13877
  • Beyeen AD, Adzemovic MZ, Ockinger J, Stridh P, Becanovic K, Laaksonen H, Lassmann H, Harris RA, Hillert J, Alfredsson L, Celius EG, Harbo HF, Kockum I, Jagodic M, Olsson T. (2010) IL-22RA2 Associates with Multiple Sclerosis and Macrophage Effector Mechanisms in Experimental Neuroinflammation. J Immunol, 185(11): 6883-6890
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  • Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W. (2010) The Protein Tyrosine Kinase Tec Regulates a CD44highCD62L- Th17 Subset J Immunol, 185(9):5111-5119
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  • Stridh P, Thessen Hedreul M, Beyeen AD, Adzemovic MZ, Laaksonen H, Gillett A, Ockinger J, Marta M, Lassmann H, Becanovic K, Jagodic M, Olsson T. (2010) Fine-mapping resolves Eae23 into two QTLs and implicates ZEB1 as a candidate gene regulating experimental neuroinflammation in rat PLoS.ONE., 5(9): e12716
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  • Bramow S, Frischer JM, Lassmann H, Koch-Henriksen N, Lucchinetti CF, Sørensen PS, Laursen H (2010) Demyelination versus remyelination in progressive multiple sclerosis Brain, 133(10): 2983-2998
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  • Höftberger R, Fink S, Aboul-Enein F, Botond G, Olah J, Berki T, Ovadi J, Lassmann H, Budka H, Kovacs GG. (2010) Tubulin polymerization promoting protein (TPPP/p25) as a marker for oligodendroglial changes in multiple sclerosis Glia, 58(15):1847-1857
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  • Höftberger R, Kunze M, Voigtländer T, Unterberger U, Regelsberger G, Bauer J, Aboul-Enein F, Garzuly F, Forss-Petter S, Bernheimer H, Berger J, Budka H (2010) Peroxisomal Localization of the Proopiomelanocortin-Derived Peptides β-Lipotropin and β-Endorphin Endocrinology, 151 (10): 4801-4810
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  • Ziabreva I, Campbell G, Rist J, Zambonin J, Rorbach J, Wydro MM, Lassmann H, Franklin RJ, Mahad D. (2010) Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes Glia, 58(15):1827-37
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  • Prevot N, Briet C, Lassmann H, Tardivel I, Roy E, Morin J, Mak TW, Tafuri A, Boitard C. (2010) Abrogation of icos/icosl costimulation in nod mice results in autoimmune deviation towards the neuromuscular system Eur. J. Immunol., 40(8): 2267-2276
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  • Sharma R, Fischer MT, Bauer J, Felts PA, Smith KJ, Misu T, Fujihara K, Bradl M, Lassmann H. (2010) Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination Acta Neuropathol, 120(2): 223-236
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  • Mohan H, Krumbholz M, Sharma R, Eisele S, Junker A, Sixt M, Newcombe J, Wekerle H, Hohlfeld R, Lassmann H, Meinl E. (2010) Extracellular Matrix in Multiple Sclerosis Lesions: Fibrillar Collagens, Biglycan and Decorin are Upregulated and Associated with Infiltrating Immune Cells Brain Pathol, 20(5): 966-975
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  • Rémi J, Pfefferkorn T, König FB, Lassmann H, Brück W, Holtmannspötter M, Straube A, Kretzschmar HA, Schüller U (2010) A 76-year-old woman with paraplegia Brain Pathol, 20(2): 507-510
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  • Khan O, Filippi M, Freedman MS, Barkhof F, Dore-Duffy P, Lassmann H, Trapp B, Bar-Or A, Zak I, Siegel MJ, Lisak R. (2010) Chronic cerebrospinal venous insufficiency and multiple sclerosis Ann Neurol, 67(3): 286-290
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  • Veto S, Acs P, Bauer J, Lassmann H, Berente Z, Setalo G Jr, Borgulya G, Sumegi B, Komoly S, Gallyas F Jr, Illes Z. (2010) Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death Brain, 133(Pt 3):: 822-834
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2010 Reviews

  • Pollak D, Rey C, Monje F (2010) Rodent models in depression research: Classical strategies and new directions Ann Med, 42 (4): 252-264
  • Misu T, Fujihara K, Takahashi T, Takano R, Nishiyama S, Takai Y, Nakashima I, Sato S, Lassmann H, Itoyama Y (2010) Pathogenesis of Neuromyelitis Optica aquaporin 4 autoimmunity and astrocytopathy Rinsho Shinkeigaku, 50(11): 872
  • Lassmann H (2010) Reply: Non-multiple sclerosis recurrent demyelinating disorders: an ongoing debate Brain, 133(8): E151
  • Grois N, Fahrner B, Arceci RJ, Henter JI, McClain K, Lassmann H, Nanduri V, Prosch H, Prayer D; for the Histiocyte Society CNS LCH Study Group. (2010) Central Nervous System Disease in Langerhans Cell Histiocytosis J Pediatr, 156(6): 873-881
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  • Lassmann H (2010) Acute disseminated encephalomyelitis and multiple sclerosis Brain, 133(2): 317-319
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  • Bradl M, Lassmann H (2010) Oligodendrocytes: biology and pathology Acta Neuropathol, 119(1): 37-53
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  • Lassmann H (2010) Axonal and neuronal pathology in multiple sclerosis: What have we learnt from animal models Exp. Neurol., 225(1): 2-8
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2010 Book Chapters

  • Bien CC, Bauer J (2010) Rasmussen Encephalitis. In: Dale, Russell C. and Vincent, Angela, Inflammatory and Autoimmune Disorders of the nervous system in children MacKeith Press, London / Clinics in Developmental Medicine No.184-185: 207-226

2009 Original Articles

  • Emmanouil M, Taoufik E, Tseveleki V, Vamvakas SS, Tselios T, Karin M, Lassmann H, Probert L. (2009) Neuronal I{kappa}B Kinase {beta} Protects Mice from Autoimmune Encephalomyelitis by Mediating Neuroprotective and Immunosuppressive Effects in the Central Nervous System J Immunol, 183(12): 7877-89
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  • Junker A, Krumbholz M, Eisele S, Mohan H, Augstein F, Bittner R, Lassmann H, Wekerle H, Hohlfeld R, Meinl E. (2009) Micro-ribonucleic acid profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47 Brain, 132(Pt 12): 3342-52
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  • Bradl M, Misu T, Takahashi T, Watanabe M, Mader S, Reindl M, Adzemovic M, Bauer J, Berger T, Fujihara K, Itoyama Y, Lassmann H. (2009) Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo Ann Neurol, 66(5): 630-643
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  • Kaushansky N, Altmann DM, Ascough S, David CS, Lassmann H, Ben-Nun A. (2009) HLA-DQB1*0602 determines disease susceptibility in a new "humanized" multiple sclerosis model in HLA-DR15 (DRB1*1501;DQB1*0602) transgenic mice J Immunol, 183(5): 3531-41
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  • Isaksson M, Ardesjö B, Rönnblom L, Kämpe O, Lassmann H, Eloranta ML, Lobell A. (2009) Plasmacytoid dendritic cells promote priming of autoimmune Th17 cells and experimental autoimmune encephalomyelitis Eur. J. Immunol., 39(10): 2925-35
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  • Fuchs P, Zorer M, Reipert S, Rezniczek GA, Propst F, Walko G, Fischer I, Bauer J, Leschnik MW, Luscher B, Thalhammer JG, Lassmann H, Wiche G. (2009) Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1C) in mice leads to reduced motor nerve conduction J Biol Chem, 284(39): 26502-9
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  • Owens GP, Bennett JL, Lassmann H, O'Connor KC, Ritchie AM, Shearer A, Lam C, Yu X, Birlea M, Dupree C, Williamson RA, Hafler DA, Burgoon MP, Gilden D. (2009) Antibodies produced by clonally expanded plasma cells in multiple sclerosis cerebrospinal fluid Ann Neurol, 65(6): 639-649
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  • Schoderboeck L, Adzemovic M, Nicolussi EM, Crupinschi C, Hochmeister S, Fischer MT, Lassmann H, Bradl M. (2009) The 'window of susceptibility' for inflammation in the immature central nervous system is characterized by a leaky blood-brain barrier and the local expression of inflammatory chemokines Neurobiol Dis, 35(3): 368-75
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  • Pöllinger B, Krishnamoorthy G, Berer K, Lassmann H, Bösl MR, Dunn R, Domingues HS, Holz A, Kurschus FC, Wekerle H. (2009) Spontaneous relapsing-remitting EAE in the SJL/J mouse: MOG-reactive transgenic T cells recruit endogenous MOG-specific B cells J Exp Med, 206(6): 1303-1316
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  • Krishnamoorthy G, Saxena A, Mars LT, Domingues HS, Mentele R, Ben-Nun A, Lassmann H, Dornmair K, Kurschus FC, Liblau RS, Wekerle H. (2009) Myelin-specific T cells also recognize neuronal autoantigen in a transgenic mouse model of multiple sclerosis Nat Med, 15(6): 626-632
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  • Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, Kümpfel T, Moldenhauer A, Rader C, Sonderegger P, Pöllmann W, Tiefenthaller C, Bauer J, Lassmann H, Wekerle H, Karagogeos D et al (2009) Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals Proc Natl Acad Sci USA, 106(20): 8302-8307
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  • Nicolussi EM, Huck S, Lassmann H, Bradl M (2009) The cholinergic anti-inflammatory system limited T cell infiltration into the neurodegenerative CNS, but can not counteract complex CNS inflammation Neurobiol Dis, 35: 24-31
  • Frischer JM, Bramow S, Dal-Bianco A, Lucchinetti CF, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Lassmann H (2009) The relation between inflammation and neurodegeneration in multiple sclerosis brains Brain, 132 (Pt. 5): 1175-1189
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  • Mahad DJ, Ziabreva I, Campbell G, Lax N, White K, Hanson PS, Lassmann H, Turnbull DM (2009) Mitochondial changes within axons in multiple sclerosis Brain, 132 (Pt. 5): 1161-1174
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  • Hochmeister S, Bittner RE, Höger H, Lassmann H, Bradl M (2009) The susceptibility to experimental autoimmune encephalomyelitis is not related to dysferlin-deficiency Autoimmunity, 42(3): 235-241

2009 Reviews

  • Bauer J, Bien CG (2009) Encephalitis and epilepsy Semin Immunopathol, 31(4) : 537-544
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  • Lassmann H (2009) Clinical and pathological topics of multiple sclerosis Rinsho Shinkeigaku, 49(11): 715-718
  • Lassmann H (2009) Experimental models of neuromyelitis optica Rinsho Shinkeigaku, 49(11): 900-901
  • Bradl M, Lassmann H (2009) Progressive multiple sclerosis Semin Immunopathol, 31(4): 455-465
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2008 Original Articles

  • Dal Bianco A, Bradl M, Frischer J, Kutzelnigg A, Jellinger K, Lassmann H. (2008) Multiple sclerosis and Alzheimer's disease. Ann Neurol, 63 (2): 174-83
  • Multiple Sclerosis Therapeutic Consensus Group (MSTCG; u.a. Lassmann H), Wiendl H, Toyka KV, Rieckmann P, Gold R, Hartung HP, Hohlfeld R (2008) Basic and escalating immunomodulatory treatments in multiple sclerosis: current therapeutic recommendations J Neurol, 255(10): 1449-1463
  • Kap YS, Smith P, Jagessar SA, Remarque E, Blezer E, Strijkers GJ, Laman JD, Hintzen RQ, Bauer J, Brok HP, 't Hart BA (2008) Fast progression of recombinant human myelin/oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis in marmosets is associated with the activation of MOG34-56-specific cy J Immunol, 180(3): 1326-1337
  • Jagessar SA, Smith PA, Blezer E, Delarasse C, Pham-Dinh D, Laman JD, Bauer J, Amor S, 't Hart B (2008) Autoimmunity against myelin oligodendrocyte glycoprotein is dispensable for the initiation although essential for the progression of chronic encephalomyelitis in common marmosets J Neuropath Exp Neurol, 67(4): 326-40.
  • Bajramovic JJ, Brok HP, Ouwerling B, Jagessar SA, van Straalen L, Kondova I, Bauer J, Amor S, 't Hart BA, Ben-Nun A. (2008) Oligodendrocyte-specific protein is encephalitogenic in rhesus macaques and induces specific demyelination of the optic nerve Eur. J. Immunol., 38(5): 1452-1464
  • Stavrou I, Baumgartner C, Frischer JM, Trattnig S, Knosp E (2008) Long-term seizure control after resection of supratentorial cavernomas: a retrospective single-center study in 53 patients. Neurosurgery, 63(5): 888-896
  • Hochmeister S, Zeitelhofer M, Bauer J, Nicolussi EM, Fischer MT, Heinke B, Selzer E, Lassmann H, Bradl M (2008) After injection into the striatum, in vitro-differentiated microglia- and bone marrow-derived dendritic cells can leave the central nervous system via the blood stream Am.J.Pathol., 173(6): 1669-1681
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  • Rathinam C, Lassmann H, Mengel M, Klein C (2008) Transcription factor Gfi1 restricts B cell-mediated autoimmunity J Immunol, 181(9): 6222-6229
  • Aharonowiz M, Einstein O, Fainstein N, Lassmann H, Reubinoff B, Ben-Hur T (2008) Neuroprotective effect of transplanted human embryonic stem cell-derived neural precursors in an animal model of multiple sclerosis PLoS.ONE., 3(9): e3145
  • Andersson A, Covacu R, Sunnemark D, Danilov AI, Dal Bianco A, Khademi M, Wallström E, Lobell A, Brundin L, Lassmann H, Harris RA (2008) Pivotal advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis J Leukoc Biol, 84(5): 1248-1255
  • Saxena A*, Bauer J*, Scheikl T, Zapulla J, Audebert M, Desbois S, Waisman A, Lassmann H, Liblau RS, Mars LT (2008) Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes J Immunol, 181(3): 1617-1621. *AS and JB share first authorship
  • Bramow S, Faber-Rod JC, Jacobsen C, Kutzelnigg A, Patrikios P, Sorensen PS, Lassmann H, Laursen H (2008) Fatal neurogenic pulmonary edema with progressive multiple sclerosis Mult Scler, 14(5): 711-715
  • Lucchinetti CF, Gavrilova RH, Metz I, Parisi JE, Scheithauer BW, Weigand S, Thomsen K, Mandrekar J, Altintas A, Erickson BJ, König F, Giannini C, Lassmann H, Linbo L, Pittock SJ, Brück W. (2008) Clinical and radiographic spectrum of pathologically confirmed tumefactive multiple sclerosis Brain, 131(Pt 7): 1759-1775
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  • Mahad D, Ziabreva I, Lassmann H, Turnbull D (2008) Mitochondrial defects in acute multiple sclerosis lesions. Brain, 131(Pt 7): 1722-1735
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  • Aboul-Enein F, Höftberger R, Buxhofer-Ausch V, Drlicek M, Lassmann H, Budka H, Kristoferitsch W. (2008) Neocortical neurones may be targeted by immune attack in anti-Yo paraneoplastic syndrome Neuropathol Appl Neurobiol, 34(2): 248-252
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  • Frischer JM, Pipp I, Stavrou I, Trattnig S, Hainfellner JA, Knosp E (2008) Cerebral cavernous malformations: congruency of histopathological features with the current clinical definition J Neurol Neurosurg Psych, 79(7): 783-788
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  • Dal Bianco A, Bradl M, Frischer J, Kutzelnigg A, Jellinger K, Lassmann H (2008) Multiple sclerosis and Alzheimer's disease Ann Neurol, 63(2): 174-183
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2008 Reviews

  • Lassmann H (2008) The pathological substrate of magnetic resonance alterations in multiple sclerosis Neuroimaging Clin N Am, 18(4): 563-576
  • Mahad D, Lassmann H, Turnbull D (2008) Mitochondria and disease progression in multiple sclerosis Neuropathol Appl Neurobiol, 34(6): 577-589
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  • Kutzelnigg A, Lassmann H (2008) Neuropathology of cognitive dysfunction in multiple sclerosis Handb Clin Neurol, 89: 719-723
  • Zivadinov R, Reder AT, Filippi M, Minagar A, Stüve O, Lassmann H, Racke MK, Dwyer MG, Frohman EM, Khan O (2008) Mechanisms of action of disease-modifying agents and brain volume changes in multiple sclerosis Neurology, 71(2): 136-144
  • Lassmann H (2008) Mechanisms of inflammation induced tissue injury in multiple sclerosis. J Neurol Sci, 274(1-2): 45-47
  • Lassmann H (2008) Model of multiple sclerosis: new insights into pathopysiology and repair Curr Opin Neurol, 21(3): 242-247
  • Lassmann H, Lucchinetti CF (2008) Cortical Demyelination ín CNS inflammatory demyelinating disease (Editorial) Neurology, 70(5): 332-333
  • Kuhlmann T, Lassmann H, Brück W (2008) Diagnosis of inflammatory demyelination in biopsy specimens: a practical approach Acta Neuropathol, 115(3): 275-287

2008 Book Chapters

  • Bradl M, Dornmair K, Hohlfeld R (2008) New tools for investigating the immuno-pathogenesis of MS: principles and applications. In: Raine C, McFarland HF, Hohlfeld R (ed.), Multiple Sclerosis: a comprehensive text Elsevier, Philadelphia, USA: 284-299

2007 Original Articles

  • Mars LT, Bauer J, Gross DA, Bucciarelli F, Firat H, Hudrisier D, Lemonnier F, Kosmatopoulos K, Liblau RS (2007) CD8 T Cell Responses to Myelin Oligodendrocyte Glycoprotein-Derived Peptides in Humanized HLA-A*0201-Transgenic Mice J Immunol, 179: 5090-5098
  • Brok HP, Boven L, van MM, Kerlero de RN, Celebi-Paul L, Kap YS, Jagessar A, Hintzen RQ, Keir G, Bajramovic J, Ben-Nun A, Bauer J, Laman JD, Amor S, 't Hart BA (2007) The human CMV-UL86 peptide 981-1003 shares a crossreactive T-cell epitope with the encephalitogenic MOG peptide 34-56, but lacks the capacity to induce EAE in rhesus monkeys J Neuroimmunol, 182: 135-152
  • Blezer EL, Bauer J, Brok HP, Nicolay K, 't Hart BA (2007) Quantitative MRI-pathology correlations of brain white matter lesions developing in a non-human primate model of multiple sclerosis. NMR Biomed, 20: 90-103
  • Seifert T, Bauer J, Weissert R, Fazekas F, Storch MK (2007) Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination Acta Neuropathol, 113: 195-203
  • Rauschka H, Aboul-Enein F, Bauer J, Nobis H, Lassmann H, Schmidbauer M (2007) Acute cerebral white matter damage in lethal salicylate intoxication Neurotoxicology, 28: 33-37
  • Einstein O, Fainstein N, Vaknin I, Mizrachi-Kol R, Reihartz E, Grigoriadis N, Lavon I, Baniyash M, Lassmann H, Ben-Hur T (2007) Neural precursors attenuate autoimmune encephalomyelitis by peripheral immunosuppression Ann Neurol, 61(3): 209-218
  • Müller GJ, Lassmann H, Johansen FF (2007) Anti-apoptotic signaling and failure of apoptosis in the ischemic rat hippocampus Neurobiol Dis, 25(3): 582-593
  • Odoardi F, Kawakami N, Li Z, Cordiglieri C, Streyl K, Nosov M, Klinkert WE, Ellwart JW, Bauer J, Lassmann H, Wekerle H, Flügel A (2007) Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis Proc Natl Acad Sci USA, 104(3): 920-925
  • Roemer SF, Parisi JE, Lennon VA, Benarroch EE, Lassmann H, Bruck W, Mandler RN, Weinshenker BG, Pittock SJ, Wingerchuk DM, Lucchinetti CF (2007) Pattern-specific loss of aquaporin-4 immunoreactivity distinguishes neuromyelitis optica from multiple sclerosis Brain, 130 (Pt 5): 1194-1205
  • Pittock SJ, Reindl M, Achenbach S, Berger T, Bruck W, Konig F, Morales Y, Lassmann H, Bryant S, Moore SB, Keegan BM, Lucchinetti CF (2007) Myelin oligodendrocyte glycoprotein antibodies in pathologically proven multiple sclerosis: frequency, stability and clinicopathologic correlations Mult Scler, 13(1): 7-16
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  • Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K (2007) The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease J Exp Med, 204(3): 571-582
  • Eltayeb S, Berg AL, Lassmann H, Wallström E, Nilsson M, Olsson T, Ericsson-Dahlstrand A, Sunnemark D (2007) Temporal expression and cellular origin of CC chemokine receptors CCR1, CCR2 and CCR5 in the central nervous system: insight into mechanisms of MOG-induced EAE J Neuroinflammation, 4: Art. 14
  • Kutzelnigg A, Faber-Rod JC, Bauer J, Lucchinetti CF, Sorensen PS, Laursen H, Stadelmann C, Brück W, Rauschka H, Schmidbauer M, Lassmann H (2007) Widespread demyelination in the cerebellar cortex in multiple sclerosis Brain Pathol, 17(1): 38-44
  • Bauer J, Elger CE, Hans VH, Schramm J, Urbach H, Lassmann H, Bien CG (2007) Astrocytes are a specific immunological target in Rasmussen's encephalitis Ann Neurol, 62(1): 67-80
  • Schmidt WM, Kraus C, Höger H, Hochmeister S, Oberndorfer F, Branka M, Bingemann S, Lassmann H, Müller M, Macedo-Souza LI, Vainzof M, Zatz M, Reis A, Bittner RE (2007) Mutation in the Scyl1 gene encoding amino-terminal kinase-like protein causes a recessive form of spinocerebellar neurodegeneration EMBO Rep, 8(7): 691-697
  • Taoufik E, Valable S, Müller GJ, Roberts ML, Divoux D, Tinel A, Voulgari-Kokota A, Tseveleki V, Altruda F, Lassmann H, Petit E, Probert L (2007) FLIP(L) protects neurons against in vivo ischemia and in vitro glucose deprivation-induced cell death J Neurosci, 27(25): 6633-6646
  • Dumser M, Bauer J, Lassmann H, Berger J, Forss-Petter S (2007) Lack of adrenoleukodystrophy protein enhances oligodendrocyte disturbance and microglia activation in mice with combined Abcd1/Mag deficiency Acta Neuropathol, 114;6: 573-586
  • Grundtner R, Dornmair K, Dahm R, Flügel A, Kawakami N, Zeitelhofer M, Schoderboeck L, Nosov M, Selzer E, Willheim M, Kiebler M, Wekerle H, Lassmann H, Bradl M (2007) Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system Neurobiol Dis, 28;3: 261-275
  • Junker A, Ivanidze J, Malotka J, Eiglmeier I, Lassmann H, Wekerle H, Meinl E, Hohlfeld R, Dornmair K (2007) Multiple sclerosis: T-cell receptor expression in distinct brain regions Brain, 130;11: 2789-2799
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  • Metz I, Lucchinetti CF, Openshaw H, Garcia-Merino A, Lassmann H, Freedman MS, Azzarelli B, Kolar OJ, Atkins HL, Brück W (2007) Autologous hematopoietic stem cell transplantation: the glass seems to be half full for aggressive, early forms of MS and half empty for advanced MS Brain, 130;5: 1254-1262
  • Marik C, Felts PA, Bauer J, Lassmann H, Smith KJ (2007) Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity? Brain, 130;11: 2800-2815
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  • Höftberger R, Garzuly F, Dienes HP, Grubits J, Rohonyi B, Fischer G, Hanzely Z, Lassmann H, Budka H (2007) Fulminant central nervous system demyelination associated with interferon-{alpha} therapy and hepatitis C virus infection Mult Scler, 13(9): 1100-1106
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2007 Reviews

  • Lassmann H (2007) Cortical, subcortical and spinal alterations in neuroimmunological diseases J Neurol, 254 (Suppl 2): II/15-II/17
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  • Lassmann H (2007) Experimental models in multiple sclerosis Rev Neurol (Paris), 163(6-7): 651-655
  • Lassmann H (2007) Multiple sclerosis: is there neurodegeneration independent from inflammation? J Neurol Sci, 259 (1-2): 1-3
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  • Lassmann H, Brück W, Lucchinetti CF (2007) The immunopathology of multiple sclerosis: an overview Brain Pathol, 17(2): 210-218
  • Lassmann H (2007) New concepts on progressive multiple sclerosis Curr Neurol Neurosci Rep, 7(3): 239-244

2006 Original Articles

  • Hohlfeld R, Kerschensteiner M, Stadelmann C, Lassmann H, Wekerle H (2006) The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis. Neurological Sciences, 27 Suppl 1: 1-7
  • Krishnamoorthy G, Lassmann H, Wekerle H, Holz A (2006) Spontaneous opticospinal encephalomyelitis in a double-transgenic mouse model of autoimmune T cell/B cell cooperation J Clin Invest, 116(9): 2385-2392
  • Patrikios P, Stadelmann C, Kutzelnigg A, Rauschka H, Schmidbauer M, Laursen H, Sorensen PS, Bruck W, Lucchinetti C, Lassmann H (2006) Remyelination is extensive in a subset of multiple sclerosis patients Brain, 129(Pt.12): 3165-3172
  • van Loo G, De Lorenzi R, Schmidt H, Huth M, Mildner A, Schmidt-Supprian M, Lassmann H, Prinz MR, Pasparakis M (2006) Inhibition of transcription factor NF-kappaB in the central nervous system ameliorates autoimmune encephalomyelitis in mice Nature Immunol, 7(9): 954-961
  • Becanovic K, Jagodic M, Sheng JR, Dahlman I, Aboul-Enein F, Wallstrom E, Olofsson P, Holmdahl R, Lassmann H, Olsson T (2006) Advanced intercross line mapping of Eae5 reveals Ncf-1 and CLDN4 as candidate genes for experimental autoimmune encephalomyelitis J Immunol, 176(10): 6055-6064
  • Spazierer D, Fuchs P, Reipert S, Fischer I, Schmuth M, Lassmann H, Wiche G (2006) Epiplakin is dispensable for skin barrier function and for integrity of keratin network cytoarchitecture in simple and stratified epithelia Mol Cell Biol, 26(2): 559-568
  • Storch MK, Bauer J, Linington C, Olsson T, Weissert R, Lassmann H (2006) Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatability complex (MHC) haplotype-related J Neuropath Exp Neurol, 65(12): 1137-1142
  • Kaushansky N, Zhong MC, Kerlero de Rosbo N, Hoeftberger R, Lassmann H, Ben-Nun A (2006) Epitope specificity of autoreactive T and B cells associated with experimental autoimmune encephalomyelitis and optic neuritis induced by oligodendrocyte-specific protein in SJL/J mice J Immunol, 15;177(10): 7364-7376
  • Aboul-Enein F., Weiser, P., Höftberger, R., Lassmann, H., and Bradl, M. (2006) Transient axonal injury in the absence of demyelination: a correlate of clinical disease in acute experimental autoimmune encephalomyelitis Acta Neuropathol, 111: 539-547
  • Fraisl P., Tanaka H., Forss-Petter S, Lassmann H., Nishimune Y., Berger J (2006) A novel mammalian bubblegum-related acyl-CoA synthetase restricted to testes and possibly involved in spermatogenesis Arch Biochem Biophys, 451: 23-33
  • Hochmeister S., Grundtner R., Bauer J., Engelhardt B., Lyck R., Gordon G., Korosec T., Kutzelnigg A., Berger J., Bradl M., Bittner R.E., Lassmann H (2006) Dysferlin Is a New Marker for Leaky Brain Blood Vessels in Multiple Sclerosis J Neuropath Exp Neurol, 65: 855-865

2006 Reviews

  • Gold R, Linington C, Lassmann H (2006) Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research. Brain, 129(Pt. 8): 1953-1971
  • Lassmann H (2006) Genetic predisposition for autoimmunity in multiple sclerosis? Lancet, 5(11): 897-898
  • Kutzelnigg A, Lassmann H (2006) Cortical demyelination in multiple sclerosis: a substrate for cognitive deficits? J Neurol Sci, 15;245(1-2): 123-126

2006 Book Chapters

  • Bradl M. (2006) Progenitors and precursos of neurons and glial cells. In: Janigro D., Cell cycle in CNS development Humana Press, Totowa, NJ, USA: 23-29

2006 Books

  • Compston A, Confavreux C, Lassmann H, McDonald I, Miller D, Noseworthy J, Smith K and Wekerle H (2006) McAlpine's Multiple Sclerosis, 4th Edition. , Churchill Livingstone, Elsevier, Philadelphia

2005 Original Articles

  • Kovacs,-G-G; Hoftberger,-R; Majtenyi,-K; Horvath,-R; Barsi,-P; Komoly,-S; Lassmann,-H; Budka,-H; Jakab,-G (2005) Neuropathology of white matter disease in Leber's hereditary optic neuropathy Brain, 128(Pt. 1): 35-41
  • Miletic,-H; Utermohlen,-O; Wedekind,-C; Hermann,-M; Stenzel,-W; Lassmann,-H; Schluter,-D; Deckert,-M (2005) P0(106-125) is a neuritogenic epitope of the peripheral myelin protein P0 and induces autoimmune neuritis in C57BL/6 mice J Neuropath Exp Neurol, 64(1): 66-73
  • Bien,-C-G; Granata,-T; Antozzi,-C; Cross,-J-H; Dulac,-O; Kurthen,-M; Lassmann,-H; Mantegazza,-R; Villemure,-J-G; Spreafico,-R; Elger,-C-E (2005) Pathogenesis, diagnosis and treatment of Rasmussen encephalitis: a European consensus statement Brain, 128 (Pt. 3): 454-471
  • Mahad,-D-J; Staugaitis,-S; Ruggieri,-P; Parisi,-J; Kleinschmidt-Demasters,-B-K; Lassmann,-H; Ransohoff,-R-M (2005) Steroid-responsive encephalopathy associated with autoimmune thyroiditis and primary CNS demyelination J Neurol Sci, 228(1): 3-5
  • Grois N, Prayer D, Prosch H, Lassmann H and the CNS LCH Co-operative Group (2005) Neuropathology of CNS disease in Langerhans cell histiocytosis. Brain, 128 (Pt. 4): 829-838
  • Pittock SJ, McClelland RL, Achenbach SJ, Konig F, Bitsch A, Bruck W, Lassmann H, Parisi JE, Scheithauer BW, Rodriguez M, Weinshenker BG, Lucchinetti CF (2005) Clinical course, pathological correlations, and outcome of biopsy proved inflammatory demyelinating disease. J Neurol Neurosurg Psych, 76 (12): 1693-1697
  • Hovelmeyer N, Hao Z, Kranidioti K, Kassiotis G, Buch T, Frommer F, von Hoch L, Kramer D, Minichiello L, Kollias G, Lassmann H, Waisman A (2005) Apoptosis of oligodendrocytes via Fas and TNF-R1 is a key event in the induction of experimental autoimmune encephalomyelitis. J Immunol, 175(9): 5875-5884
  • Kutzelnigg A, Lucchinetti CF, Stadelmann C, Bruck W, Rauschka H, Bergmann M, Schmidbauer M, Parisi JE, Lassmann H (2005) Cortical demyelination and diffuse white matter injury in multiple sclerosis Brain, 128 (Pt .11): 2705-2712
  • Kantarci OH, Morales Y, Ziemer PA, Hebrink DD, Mahad DJ, Atkinson EJ, Achenbach SJ, De Andrade M, Mack M, Ransohoff RM, Lassmann H, Bruck W, Weinshenker BG, Lucchinetti CF (2005) CCR5Delta32 polymorphism effects on CCR5 expression, patterns of immunopathology and disease course in multiple sclerosis J Neuroimmunol, 169 (1-2): 137-143
  • Gies U, Gruia D, Lassmann H, Bergmann M (2005) A case of rapidly progressive Rosai-Dorfman disease restricted to the central nervous system Zentralbl Neurochir, 66(3): 142-146
  • Ali S, King GD, Curtin JF, Candolfi M, Xiong W, Liu C, Puntel M, Cheng Q, Prieto J, Ribas A, Kupiec-Weglinski J, van Rooijen N, Lassmann H, Lowenstein PR, Castro MG (2005) Combined immunostimulation and conditional cytotoxic gene therapy provide long-term survival in a large glioma model Cancer Res, 65(16): 7194-7204
  • Keegan M, Konig F, McClelland R, Bruck W, Morales Y, Bitsch A, Panitch H, Lassmann H, Weinshenker B, Rodriguez M, Parisi J, Lucchinetti CF (2005) Relation between humoral pathological changes in multiple sclerosis and response to therapeutic plasma exchange Lancet, 366(9485): 579-582
  • Sunnemark D, Eltayeb S, Nilsson M, Wallstrom E, Lassmann H, Olsson T, Berg AL, Ericsson-Dahlstrand A (2005) CX3CL1 (fractalkine) and CX3CR1 expression in myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis: kinetics and cellular origin J Neuroinflammation, 2: 17
  • Perron H, Lazarini F, Ruprecht K, Pechoux-Longin C, Seilhean D, Sazdovitch V, Creange A, Battail-Poirot N, Sibai G, Santoro L, Jolivet M, Darlix JL, Rieckmann P, Arzberger T, Hauw JJ, Lassmann H (2005) Human endogenous retrovirus (HERV)-W ENV and GAG proteins: physiological expression in human brain and pathophysiological modulation in multiple sclerosis lesions J Neurovirol, 11(1): 23-33
  • Stadelmann C, Ludwin S, Tabira T, Guseo A, Lucchinetti CF, Leel-Ossy L, Ordinario AT, Bruck W, Lassmann H (2005) Tissue preconditioning may explain concentric lesions in Balo's type of multiple sclerosis Brain, 128(Pt. 5): 979-987
  • Sosnová, M., Bradl, M., and Forrester, J.V (2005) CD34+ corneal stromal cells are haematopoietic stem cells Stem Cells, 23: 507-515
  • Bradl, M., Bauer, J., Flügel A., Wekerle H., and Lassmann, H (2005) Complementary contribution of CD4 and CD8 T lymphocytes to T cell infiltration of the intact and the degenerative spinal cord Am.J.Pathol., 166: 1441-1450
  • Kawakami, N., Odoardi, F., Ziemssen, T., Bradl, M., Ritter, T., Neuhaus, O., Lassmann, H., Wekerle, H., and Flügel, A. (2005) Autoimmune CD4+ T cell memory: Life long persistence of encephalitogenic T cell clones in healthy immune repertoires J Neuroimmunol, 175: 69-81

2005 Reviews

  • Bien CG, Bauer J. (2005) T-cells in human encephalitis Neuromolecular Med., : 7(3):243-53
  • Aboul-Enein,-F; Lassmann,-H (2005) Mitochondrial damage and histotoxic hypoxia: a pathway of tissue injury in inflammatory brain disease? Acta Neuropathol, 109(1): 49-55
  • Lassmann H (2005) Multiple sclerosis pathology: evolution of pathogenetic concepts. Brain Pathol, 15(3): 217-222
  • Lassmann H (2005) Stem cell and progenitor cell transplantation in multiple sclerosis: the discrepancy between neurobiological attraction and clinical feasibility. J Neurol Sci, 233(1-2): 83-86
  • Kutzelnigg A, Lassmann H (2005) Cortical lesions and brain atrophy in MS J Neurol Sci, 233(1-2): 55-59

2005 Book Chapters

  • Lassmann H (2005) Pathology of Neurons in Multiple Sclerosis. In: S. Waxman, Multiple Sclerosis as a Neuronal Disease Elsevier, Academic Press, Amsterdam: 153-164
  • Bradl M, Lassmann H (2005) The role of autoimmunity in multiple sclerosis. In: Zouali, M., Molecular Autoimmunity Springer Science & Business Media, New York, USA: 209-225

2004 Original Articles

  • Muller,-G-J; Stadelmann,-C; Bastholm,-L; Elling,-F; Lassmann,-H; Johansen,-F-F (2004) Ischemia leads to apoptosis--and necrosis-like neuron death in the ischemic rat hippocampus Brain Pathol, 14(4): 415-424
  • Tseveleki,-V; Bauer,-J; Taoufik,-E; Ruan,-C; Leondiadis,-L; Haralambous,-S; Lassmann,-H; Probert,-L (2004) Cellular FLIP (long isoform) overexpression in T cells drives Th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis J Immunol, 173(11): 6619-6926
  • Preusser,-M; Strobel,-T; Birner,-P; Marosi,-C; Dieckmann,-K; Rossler,-K; Budka,-H; Lassmann,-H; Hainfellner,-J-A (2004) Presence of D110 antigen expressing immunocompetent cells in glioblastoma associates with prolonged survival Neuropathol Appl Neurobiol, 30(6): 608-614
  • Loers,-G; Aboul-Enein,-F; Bartsch,-U; Lassmann,-H; Schachner,-M (2004) Comparison of myelin, axon, lipid, and immunopathology in the central nervous system of differentially myelin-compromised mutant mice: a morphological and biochemical study Mol Cell Neurosci, 27(2): 175-189
  • Lucchinetti,-C-F; Bruck,-W; Lassmann,-H (2004) Evidence for pathogenic heterogeneity in multiple sclerosis Ann Neurol, 56(2): 308
  • Mead,-R-J; Neal,-J-W; Griffiths,-M-R; Linington,-C; Botto,-M; Lassmann,-H; Morgan,-B-P (2004) Deficiency of the complement regulator CD59a enhances disease severity, demyelination and axonal injury in murine acute experimental allergic encephalomyelitis Lab Invest, 84(1): 21-28
  • Tschachler,-E; Reinisch,-C-M; Mayer,-C; Paiha,-K; Lassmann,-H; Weninger,-W (2004) Sheet preparations expose the dermal nerve plexus of human skin and render the dermal nerve end organ accessible to extensive analysis J Invest Dermatol, 122(1): 177-182
  • Hoftberger,-R; Aboul-Enein,-F; Brueck,-W; Lucchinetti,-C; Rodriguez,-M; Schmidbauer,-M; Jellinger,-K; Lassmann,-H (2004) Expression of major histocompatibility complex class I molecules on the different cell types in multiple sclerosis lesions Brain Pathol, 14(1): 43-50
  • Cabarrocas,-J; Piaggio,-E; Zappulla,-J-P; Desbois,-S; Mars,-L-T; Lassmann,-H; Liblau,-R-S (2004) A transgenic mouse model for T-cell ignorance of a glial autoantigen J Autoimmun, 22(3): 179-189
  • Mahad,-D-J; Trebst,-C; Kivisakk,-P; Staugaitis,-S-M; Tucky,-B; Wei,-T; Lucchinetti,-C-F; Lassmann,-H; Ransohoff,-R-M (2004) Expression of chemokine receptors CCR1 and CCR5 reflects differential activation of mononuclear phagocytes in pattern II and pattern III multiple sclerosis lesions J Neuropath Exp Neurol, 63(3): 262-273
  • Aszmann,-O-C; Winkler,-T; Korak,-K; Lassmann,-H; Frey,-M (2004) The influence of GDNF on the timecourse and extent of motoneuron loss in the cervical spinal cord after brachial plexus injury in the neonate Neurol Res, 26(2): 211-217
  • Kivisakk,-P; Mahad,-D-J; Callahan,-M-K; Sikora,-K; Trebst,-C; Tucky,-B; Wujek,-J; Ravid,-R; Staugaitis,-S-M; Lassmann,-H; Ransohoff,-R-M (2004) Expression of CCR7 in multiple sclerosis: implications for CNS immunity Ann Neurol, 55 (5): 627-638
  • Akassoglou,-K; Adams,-R-A; Bauer,-J; Mercado,-P; Tseveleki,-V; Lassmann,-H; Probert,-L; Strickland,-S (2004) Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis Proc Natl Acad Sci USA, 101(17): 6698-6703
  • de-Rosbo,-N-K; Kaye,-J-F; Eisenstein,-M; Mendel,-I; Hoeftberger,-R; Lassmann,-H; Milo,-R; Ben-Nun,-A (2004) The myelin-associated oligodendrocytic basic protein region MOBP15-36 encompasses the immunodominant major encephalitogenic epitope(s) for SJL/J mice and predicted epitope(s) for multiple sclerosis-as J Immunol, 172(2): 1426-1435
  • Pellkofer,-H; Schubart,-A-S; Hoftberger,-R; Schutze,-N; Pagany,-M; Schuller,-M; Lassmann,-H; Hohlfeld,-R; Voltz,-R; Linington,-C (2004) Modelling paraneoplastic CNS disease: T-cells specific for the onconeuronal antigen PNMA1 mediate autoimmune encephalomyelitis in the rat Brain, 127 (Pt. 8): 1822-1830
  • Xanthoulea,-S; Pasparakis,-M; Kousteni,-S; Brakebusch,-C; Wallach,-D; Bauer,-J; Lassmann,-H; Kollias,-G (2004) Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases J Exp Med, 200 (3): 367-376
  • Kawakami, N., Lassmann, S., Li, Z., Odoardi, F., Ritter, T., Ziemssen, T., Klinkert, W.E.F., Ellwart, J.W., Bradl, M., Krivacic, K., Lassmann, H., Ransohoff, R.M., Volk, H.-D., Wekerle, H., Linington (2004) The activation status of neuroantigen-specific T cells in the target organ determines the clinical outcome of autoimmune encephalomyelitis J Exp Med, 199: 185-197
  • Aboul-Enein, F., Bauer, J., Klein, M., Schubart, A., Flügel, A., Ritter, T., Kawakami, N., Siedler, F., Linington, C., Wekerle, H., Lassmann, H., Bradl, M (2004) Selective and antigen dependent effects of myelin degeneration on central nervous system inflammation J Neuropath Exp Neurol, 63: 1284-1296

2004 Reviews

  • Lassmann,-H; Ransohoff,-R-M (2004) The CD4-Th1 model for multiple sclerosis: a critical [correction of crucial] re-appraisal Trends Immunol, 25(3): 132-137
    | Article (PDF) |
  • Lassmann,-H (2004) Recent neuropathological findings in MS-implications for diagnosis and therapy. J Neurol, 251 Suppl 4: IV2-5
  • Rieckmann,-P; Toyka,-K-V; Bassetti,-C; Beer,-K; Beer,-S; Buettner,-U; Chofflon,-M; Gotschi-Fuchs,-M; Kappos,-L; Kesselring,-J;...........Lassmann H et al (Multiple-Sclerosis-Therapy-Consensus-Group) (2004) Escalating immunotherapy of multiple sclerosis-new aspects and practical application J Neurol, 251(11): 1329-1339

2004 Books

  • Lazzarini RA, Griffin JW, Lassmann H, Nave KA, Miller RH, Trapp BD (Eds.) (2004) Myelin Biology and Disorders. , Elsevier, Academic Press, Amsterdam

2003 Original Articles

  • Becanovic K, Wallstrom E, Kornek B, Glaser A, Broman KW, Dahlman I, Olofsson P, Holmdahl R, Luthman H, Lassmann H, Olsson T (2003) New loci regulating rat myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis J Immunol, 170(2): 1062-1069
  • Lobell A, Weissert R, Eltayeb S, de Graaf KL, Wefer J, Storch MK, Lassmann H, Wigzell H, Olsson T (2003) Suppressive DNA vaccination in myelin oligodendrocyte glycoprotein peptide-induced experimental autoimmune encephalomyelitis involves a T1-biased immune response J Immunol, 170(4): 1806-1813
  • Trebst C, Staugaitis SM, Kivisakk P, Mahad D, Cathcart MK, Tucky B, Wei T, Rani MR, Horuk R, Aldape KD, Pardo CA, Lucchinetti CF, Lassmann H, Ransohoff RM (2003) CC Chemokine Receptor 8 in the Central Nervous System Is Associated with Phagocytic Macrophages Am.J.Pathol., 162(1): 427-438
  • Aboul-Enein F, Rauschka H, Kornek B, Stadelmann C, Stefferl A, Bruck W, Lucchinetti C, Schmidbauer M, Jellinger K, Lassmann H (2003) Preferential loss of myelin-associated glycoprotein reflects hypoxia-like white matter damage in stroke and inflammatory brain diseases J Neuropath Exp Neurol, 62(1): 25-33
  • Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, Probert L (2003) Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice Proc Natl Acad Sci USA, 100(2): 709-714
  • Eltayeb,-S; Sunnemark,-D; Berg,-A-L; Nordvall,-G; Malmberg,-A; Lassmann,-H; Wallstrom,-E; Olsson,-T; Ericsson-Dahlstrand,-A (2003) Effector stage CC chemokine receptor-1 selective antagonism reduces multiple sclerosis-like rat disease J Neuroimmunol, 142(1-2): 75-85
  • Schroeter,-M; Stoll,-G; Weissert,-R; Hartung,-H-P; Lassmann,-H; Jander,-S (2003) CD8+ phagocyte recruitment in rat experimental autoimmune encephalomyelitis: association with inflammatory tissue destruction Am.J.Pathol., 163(4): 1517-1524
  • Abdul-Majid,-K-B; Wefer,-J; Stadelmann,-C; Stefferl,-A; Lassmann,-H; Olsson,-T; Harris,-R-A (2003) Comparing the pathogenesis of experimental autoimmune encephalomyelitis in CD4(-/-) and CD8(-/-) DBA/1 mice defines qualitative roles of different T cell subsets J Neuroimmunol, 141 (1-2): 10-19
  • Rauschka,-H; Jellinger,-K; Lassmann,-H; Braier,-F; Schmidbauer,-M (2003) Guillain-Barre syndrome with marked pleocytosis or a significant proportion of polymorphonuclear granulocytes in the cerebrospinal fluid: neuropathological investigation of five cases and review of di Eur J Neurol, 10(5): 479-486
  • Wanschitz,-J; Maier,-H; Lassmann,-H; Budka,-H; Berger,-T (2003) Distinct time pattern of complement activation and cytotoxic T cell response in Guillain-Barre syndrome. Brain, 126(Pt.9): 2034-2042
  • Kivisakk,-P; Mahad,-D-J; Callahan,-M-K; Trebst,-C; Tucky,-B; Wei,-T; Wu,-L; Baekkevold,-E-S; Lassmann,-H; Staugaitis,-S-M; Campbell,-J-J; Ransohoff,-R-M (2003) Human cerebrospinal fluid central memory CD4+ T cells: evidence for trafficking through choroid plexus and meninges via P-selectin Proc Natl Acad Sci USA, 100(14): 8389-8394
  • Becanovic,-K; Backdahl,-L; Wallstrom,-E; Aboul-Enein,-F; Lassmann,-H; Olsson,-T; Lorentzen,-J-C (2003) Paradoxical effects of arthritis-regulating chromosome 4 regions on myelin oligodendrocyte glycoprotein-induced encephalomyelitis in congenic rats Eur. J. Immunol., 33(7): 1907-1916
  • Cabarrocas,-J; Bauer,-J; Piaggio,-E; Liblau,-R; Lassmann,-H (2003) Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes Eur. J. Immunol., 33(5): 1174-1182
  • Aszmann,-O-C; Korak,-K-J; Rab,-M; Grunbeck,-M; Lassmann,-H; Frey,-M (2003) Neuroma prevention by end-to-side neurorraphy: an experimental study in rats J Hand Surg, 28(6): 1022-1028
  • Trebst,-C; Staugaitis,-S-M; Tucky,-B; Wei,-T; Suzuki,-K; Aldape,-K-D; Pardo,-C-A; Troncoso,-J; Lassmann,-H; Ransohoff,-R-M (2003) Chemokine receptors on infiltrating leucocytes in inflammatory pathologies of the central nervous system (CNS) Neuropathol Appl Neurobiol, 29(6): 584-595
  • Carboni,-S; Aboul-Enein,-F; Waltzinger,-C; Killeen,-N; Lassmann,-H; Pena-Rossi,-C (2003) CD134 plays a crucial role in the pathogenesis of EAE and is upregulated in the CNS of patients with multiple sclerosis J Neuroimmunol, 145: 1-11
  • Sunnemark,-D; Eltayeb,-S; Wallstrom,-E; Appelsved,-L; Malmberg,-A; Lassmann,-H; Ericsson-Dahlstrand,-A; Piehl,-F; Olsson,-T (2003) Differential expression of the chemokine receptors CX3CR1 and CCR1 by microglia and macrophages in myelin-oligodendrocyte-glycoprotein-induced experimental autoimmune encephalomyelitis Brain Pathol, 13(4): 617-629
  • Lassmann H., Reindl M., Rauschka H., Berger J., Aboul-Enein F., Berger T., Zurbriggen A., Luterotti A., Brück W., Weber JR., Ullrich R., Schmidbauer M., Jellinger K., Vanddevelde M. (2003) A new paraclinical CSF marker for hypoxia-like tissue damage in multiple sclerosis lesions Brain, 126: 1347-1357

2003 Reviews

  • Kornek,-B; Lassmann,-H (2003) Neuropathology of multiple sclerosis-new concepts Brain Res Bull, 61(3): 321-326
  • Bradl, M.,Hohlfeld, R (2003) Neuroscience for Neurologists: molecular pathogenesis of neuroinflammation J Neurol Neurosurg Psych, 74: 1364-1370

2002 Original Articles

  • Storch MK, Weissert R, Stefferl A, Birnbacher R, Wallstrom E, Dahlman I, Ostensson CG, Linington C, Olsson T, Lassmann H (2002) MHC gene related effects on microglia and macrophages in experimental autoimmune encephalomyelitis determine the extent of axonal injury Brain Pathol, 12(3): 287-299
  • Svensson L, Abdul-Majid KB, Bauer J, Lassmann H, Harris RA, Holmdahl R (2002) A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination Eur. J. Immunol., 32(7): 1939-1946
  • Lucchinetti CF, Mandler RN, McGavern D, Bruck W, Gleich G, Ransohoff RM, Trebst C, Weinshenker B, Wingerchuk D, Parisi JE, Lassmann H (2002) A role for humoral mechanisms in the pathogenesis of Devic's neuromyelitis optica Brain, 125: 1450-1461
  • Mars LT, Laloux V, Goude K, Desbois S, Saoudi A, Van Kaer L, Lassmann H, Herbelin A, Lehuen A, Liblau RS (2002) Cutting edge: V alpha 14-J alpha 281 NKT cells naturally regulate experimental autoimmune encephalomyelitis in nonobese diabetic mice J Immunol, 15;168(12): 6007-6011
  • Sorensen TL, Trebst C, Kivisakk P, Klaege KL, Majmudar A, Ravid R, Lassmann H, Olsen DB, Strieter RM, Ransohoff RM, Sellebjerg F (2002) Multiple sclerosis: a study of CXCL10 and CXCR3 co-localization in the inflamed central nervous system J Neuroimmunol, 127(1-2): 59-68
  • Linker RA, Maurer M, Gaupp S, Martini R, Holtmann B, Giess R, Rieckmann P, Lassmann H, Toyka KV, Sendtner M, Gold R (2002) CNTF is a major protective factor in demyelinating CNS disease: a neurotrophic cytokine as modulator in neuroinflammation Nat Med, 8(6): 620-624
  • Bien CG, Bauer J, Deckwerth TL, Wiendl H, Deckert M, Wiestler OD, Schramm J, Elger CE, Lassmann H (2002) Destruction of neurons by cytotoxic T cells: a new pathogenic mechanism in Rasmussen's encephalitis Ann Neurol, 51(3): 311-318
  • Abdul-Majid KB, Stefferl A, Bourquin C, Lassmann H, Linington C, Olsson T, Kleinau S, Harris RA (2002) Fc receptors are critical for autoimmune inflammatory damage to the central nervous system in experimental autoimmune encephalomyelitis Scand J Immunol, 55(1): 70-81
  • Schobesberger M, Zurbriggen A, Doherr MG, Weissenbock H, Vandevelde M, Lassmann H, Griot C (2002) Demyelination precedes oligodendrocyte loss in canine distemper virus-induced encephalitis Acta Neuropathol, 103(1): 11-19
  • Stadelmann C, Kerschensteiner M, Misgeld T, Bruck W, Hohlfeld R, Lassmann H (2002) BDNF and gp145trkB in multiple sclerosis brain lesions: neuroprotective interactions between immune and neuronal cells? Brain, 125: 75-85
  • Holzfeind PJ, Grewal PK, Reitsamer HA, Kechvar J, Lassmann H, Hoeger H, Hewitt JE, Bittner RE (2002) Skeletal, cardiac and tongue muscle pathology, defective retinal transmission, and neuronal migration defects in the Large(myd) mouse defines a natural model for glycosylation-deficient muscle - eye – Hum Mol Genet, 11(21): 2673-2687
  • Bien CG, Urbach H, Deckert M, Schramm J, Wiestler OD, Lassmann H, Elger CE (2002) Diagnosis and staging of Rasmussen's encephalitis by serial MRI and histopathology Neurology, 2: 250-257
  • Mead RJ, Singhrao SK, Neal JW, Lassmann H, Morgan BP (2002) The membrane attack complex of complement causes severe demyelination associated with acute axonal injury J Immunol, 168(1): 458-465
  • Neumann H, Medana IM, Bauer J, Lassmann H (2002) Cytotoxic T lymphocytes in autoimmune and degenerative CNS diseases Trends Neurosci, 25(6): 313-319
  • Bauer, J., Bradl, M., Klein, M., Leisser, M., Deckwerth, T.I., Wekerle, H. and Lassmann, H (2002) Endoplasmic reticulum stress in PLP overexpressing transgenic rats: Gray matter oligodendrocytes are more vulnerable than white matter oligodendrocytes J Neuropath Exp Neurol, 61: 12-22

2002 Reviews

  • Bruck W, Lucchinetti C, Lassmann H (2002) The pathology of primary progressive multiple sclerosis Mult Scler, 8(2): 93-97
  • Bauer J, Bien CG, Lassmann H (2002) Rasmussen's encephalitis: a role for autoimmune cytotoxic T lymphocytes Curr Opin Neurol, 15(2): 197-200
  • Schwerer B (2002) Antibodies against gangliosides: a link between preceding infection and immunopathogenesis of Guillain-Barré syndrome Microbes Infect, 4: 373-384

2002 Book Chapters

  • Bradl M, Flügel A. (2002) The role of T-cells in brain pathology. In: Richt J, Dietzschold B, Protective and pathological immune responses in the CNS. Current Topics in Microbiology and Immunology Springer Verlag, Heidelberg, Germany: 141-162

2001 Original Articles

  • Flugel A, Matsumoro K, Neumann H, Klinkert WE, Birnbacher R, Lassmann H, Otten U, Wekerle H (2001) Anti inflammatory activity of nerve growth factor in experimental autoimmune encephalomyelitis: inhibition of monocyte transendeothelial migration Eur. J. Immunol., 31: 11-22
  • Kornek B, Storch MK, Bauer J, Djamshidian A, Weissert R, Wallstrom E, Stefferl A, Zimprich F, Olsson T, Linington C, Schmidbauer M, Lassmann H (2001) Distribution of calcium channel subunit in dystrophic axons in multiple sclerosis and experiemntal autoimmune encephalomyelitis Brain, 124: 1114-1124
  • Flugel A, Berkowicz T, Ritter T, Labeur M, Jenne DE, Li Z, Ellwart JW, Willem M, Lassmann H, Wekerle H (2001) Migratory activity and functional changes of green fluorescent effector cells before and during experiemntal autoimmune encephalomyelitis Immunity, 14: 547-560
  • Weissert R, de Graaf KL, Storch MK, Barth S, Linington C, Lassmann H, Olsson T (2001) MHC Class II-regulated central nervous system autoaggression and T cell responses in peripheral lymphoid tissues are dissociated in myelin oligodendrocyte glycoprotein-induced experimental autoimmune J Immunol, 166: 7588-7599
  • Bitsch A, Kuhlmann T, Stadelmann C, Lassmann H, Lucchinetti C, Bruck W (2001) A longitudinal MRI study of histopathologically defined hypointense multiple sclerosis lesions Ann Neurol, 49: 793-796
  • Stadelmann C, Mews I, Srinivasan A, Deckwerth TL, Lassmann H, Bruck W (2001) Expression of cell death-associated proteins in neuronal apoptosis associated with pontosubicular neuron necrosis Brain Pathol, 11: 273-281
  • Stefferl A, Storch MK, Linington C, Stadelmann C, Lassmann H, Pohl T, Holsboer F, Tilders FJ, Reul JM (2001) Disease progression in chronic relapsing experimental allergic encephalomyelitis is associated with reduced inflammation-driven production of corticosterone Endocrinology, 142: 3616-3624
  • Eugster HP, Frei K, Winkler F, Koedel U, Pfister W, Lassmann H, Fontana A (2001) Superantigen overcomes resistance of Il-6-deficient mice towards MOG-induced EAE by a TNFR1 controlled pathway Eur. J. Immunol., 31: 2302-2312
  • Jagodic M, Kornek B, Weissert R, Lassmann H, Olsson T, Dahlman I (2001) Congenic mapping confirms a locus on rat chromosome 10 conferring strong protection against myelin oligodendrocyte glycoprotein-induced experiemntal autoimmune encephalomyelitis Immunogenetics, 53: 410-415
  • Gerber J, Bruck W, Stadelmann C, Bunkowski S, Lassmann H, Nau R (2001) Expression of cell death proteins in dentate granule cells in human bacterial meningitis Brain Pathol, 11: 422-431
  • Cornet A, Savidge TC, Cabarrocas J, Dend WL, Colombel JF, Lassmann H, Desreumaux P, Liblau RS (2001) Enterocolitis induced by autoimmune targeting of enteric glia cells: a possible mechanism in Crohn’s disease? Proc Natl Acad Sci USA, 98: 13306-13311
  • Trebst C, Sorensen TL, Kivisakk P, Cathcart MK, Hesselgesser J, Horuk R, Selleberg F, Lassmann H, Ransohoff RM (2001) CCR1+/CCR5+ mononuclear phagocates accumulate in the central nervous system of patients with multiple sclerosis Am.J.Pathol., 159: 1701-1710
  • Flügel, A., Bradl, M., Kreutzberg, G.W. and Graeber, M.B. (2001) Transformation of donor-derived bone marrow precursors into host microglia during autoimmune CNS inflammation and during the retrograde response to axotomy J Neurosci Res, 66: 74-82

2001 Reviews

  • Lassmann H (2001) Classification of demyelinating diseases at the interface between etiology and pathogenesis Curr Opin Neurol, 14: 253-258
  • Flügel, A. and Bradl, M (2001) New tools to trace populations of inflammatory cells in the CNS Glia, 36: 125-136

2000 Original Articles

  • Kornek B, Storch M, Weissert R, Wallstroem E, Stefferl A, Olsson T, Linington C, Schmidbauer M, Lassmann H (2000) Multiple sclerosis and chronic autoimmune encephalomyelitis: A comparative quantitative study of axonal injury in active, inactive and remyelinated lesions Am.J.Pathol., 157: 267-276
  • Meixner A, Haverkamp S, Wassle H, Fuhrer S, Thalhammer J, Kropf N, Bittner RE, Lassmann H, Wiche G, Propst F (2000) MAP1B is reqired for axon guidance and is involved in the development of the central and peripheral nervous system J Cell Biol, 151: 1169-1178
  • Abdul-Majid K, Jirholt J, Stadelmann C, Stefferl A, Kjellen P, Wallstrom E, Holmdahl R, Lassmann H, Olsson T, Harris RA (2000) Screeining of several H-2 congenic mouse strains identified H-2q mice as highly susceptible to MOG-induced EAE with minimal adjuvant requirement J Neuroimmunol, 111: 23-33
  • Probert L, Eugster HP, Akassoglou K, Bauer J, Frei K, Lassmann H, Fontana A (2000) TNFR1 signalling is critical for the development of demyelination and the limitation of T-cell responses during immune mediated CNS disease Brain, 123: 2005-2019
  • Stefferl A, Schubart A, Storch M, Amini A, Mather I, Lassmann H, Linington C (2000) Butyrophylin, a milk protein, modulates the encephalitogenic T cell response to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis J Immunol, 165: 2859-2865
  • Babbe H, Roers A, Waisman A, Lassmann H, Goebels N, Hohlfeld R, Friese M, Schroder R, Deckert M, Schmidt S, Ravid R, Rajewsky K (2000) Clonal expansion of CD8+ T cells dominate the T cell infiltrate in active multiple sclerosis lesions as shown by micromanipulation and single cell polymerase chain reaction J Exp Med, 192: 393-404
  • Neisser A., Schwerer B., Bernheimer H., Moran A.P (2000) Ganglioside-induced antiganglioside antibodies from a neuropathy patient cross-react with lipopolysaccharides of Campylobacter jejuni associated with Guillain-Barré syndrome J Neuroimmunol, 102: 85-88

2000 Reviews

  • Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H (2000) Heterogeneity of multiple sclerosis lesions: Implications for the pathogenesis of demyelination Ann Neurol, 47: 707-717
  • Stadelmann C, Lassmann H (2000) Detection of apoptosis in tissue sections Cell Tissue Res, 301: 19-31
  • Hohlfeld R, Kerschensteiner M, Stadelmann C, Lassmann H, Wekerle H (2000) The neuroprotective effect of inflammation: implications for the pathogenesis of demyelination J Neuroimmunol, 107: 161-166

1999 Original Articles

  • Eugster HP, Frei K, Bachmann R, Bluethmann H, Lassmann H, Fontana A (1999) Severity of symptoms and demyelination depends in MOG induced EAE depends on TNFR1 Eur. J. Immunol., 29: 626-632
  • Bachmann R, Eugster HP, Frei K, Fontana A, Lassmann H (1999) Impaiment of TNF-receptor 1 signalling but not Fas-signalling diminishes T-cell apoptosis in MOG-peptide induced chronic demyelinating autoimmune encephalomyelitis in mice Am.J.Pathol., 154: 1417-1422
  • Kerschensteiner M, Gallmeier E, Behrens L, Klinkert WEF, Kolbeck R, Hoppe E, Oropeza-Wekerle RL, Bartke I, Stadelmann C, Lassmann H, Wekerle H, Hohlfeld R (1999) Activated human T cells, B cells and monocytes produce brain-derived neurotrophic factor (BDNF) in vitr and in brain lesions: A neuroprotective role of inflammation ? J Exp Med, 189: 865-870
  • Weerth S, Berger T, Lassmann H, Linington C (1999) Encephalitogenic and neuritogenic T-cell responses to the myelin-associated glycoprotein (MAG) in the Lewis rat J Neuroimmunol, 95: 157-164
  • Bauer J, Stadelmann C, Bancher C, Jellinger K, Lassmann H (1999) Apoptosis of T-lymphocytes in acute disseminated encephalomyelitis Acta Neuropathol, 97: 543-546
  • Kassiotis G, Bauer J, Akassoglou K, Lassmann H, Kollias G, Probert L (1999) A tumor necrosis factor-induced model of human primary demyelinating disease develops in immunodeficient backgrounds Eur. J. Immunol., 29: 912-917
  • Bradl M, Bauer J, Inomata T, Zielasek J, Nave KA, Toyka K, Lassmann H, Wekerle H (1999) Transgenic Lewis rats overexpressing the proteolipid protein gene : myelin degeneration and its effects on T-cell mediated experimental autoimmune encephalomyelitis Acta Neuropathol, 97: 595-606
  • Schmidt S, Hertfelder HJ, von Spiegel T, Hering R, Harzheim M, Lassmann H, Deckert-Schlüter M, Schlegel U (1999) Lethal capillary leak syndrome following a single administration of interferon beta-1b Neurology, 53: 220-222
  • Kuhlmann T, Lucchinetti CF, Zettl UK, Bitsch A, Lassmann H, Brück W (1999) Bcl-2 expressing oligodendrocytes in multiple sclerosis Glia, 28: 34-39
  • Bittner R, Anderson LVB, Burkhardt E, Bashir R, Vafiadaki E, Raffelsberger T, Maerk I, Höger H, Jung M, Karbasiyan M, Storch M, Lassmann H, Moss JA, Davison K, Harrison R, Bushby KMD, Reis A (1999) Dysferlin gene-deletion in the SJL mouse (dysf/sjl) defines a naturally occuring model for limb girdle muscular dystrophy 2B (LGMD 2B) and Miyoshi Myopathy Nature Genetics, 23: 141-142
  • Stefferl A, Brehm U, Storch M, Lambracht-Washington D, Bourquin C, Wonigeit K, Lassmann H, Linington C (1999) Myelin oligodendrocyte glycoprotein induces experimental autoimmune encephalomyelitis in the resistant Brown Norway rat: Disease susceptibility is determined by MHC and MHC-linked effects on the B-cel J Immunol, 163: 40-49
  • Lucchinetti C, Brück W, Parisi J, Scheithauer B, Rodriguez M, Lassmann H (1999) A quantitative analysis of oligodendrocytes in multiple sclerosis lesions. A study of 117 cases Brain, 122: 2279-2295
  • Stadelmann C, Deckwerth TL, Srinivasan A, Bancher C, Brück W, Jellinger K, Lassmann H (1999) Activation of caspase-3 in single neurons and autophagic granules of granulovacuolar degeneration in Alzheimer’s disease Am.J.Pathol., 155: 1459-1466
  • Dewey RA, Morrissey G, Coswill CM, Stone D, Bolognami F, Dodd NJF, Southgate TD, Klatzmann D, Lassmann H, Castro MG, Löwenstein PR (1999) Chronic brain inflammation and persistent HSV1-TK expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: Implications for clinical trials Nat Med, 5: 1256-1263
  • Schwerer B., Neisser A., Bernheimer H (1999) Distinct immunoglobulin class and immunoglobulin G subclass patterns against ganglioside GQ1b in Miller Fisher syndrome following different types of infection Infect Immun, 67: 2414-2420
  • Finsterer J., Schwerer B., Bittner R.E., Mamoli B (1999) Cerebrospinal fluid filtration and immunoglobulins in multifocal motor neuropathy Clin Neuropathol, 18: 31-36

1999 Reviews

  • Bradl M (1999) Myelin dysfunction/degradation in the central nervous system: Why are myelin sheaths susceptible to damage? J Neural Transm, Suppl 55: 9-17

1998 Original Articles

  • Storch MK, Piddlesden S, Haltia M, Iivanainen M, Morgan P, Lassmann H (1998) Multiple sclerosis: in situ evidence for antibody and complement mediated demyelination. Ann Neurol, 43: 465-471
  • Stadelmann C, Brück W, Bancher C, Jellinger K, Lassmann H (1998) Alzheimer’s disease: DNA fragmentation indicates increased neuronal vulnerability, but not apoptosis J Neuropath Exp Neurol, 86: 213-217
  • Lassmann H, Raine CS, Antel J, Prineas JW (1998) Immunopathology of multiple sclerosis: Report on an international meeting held at the Institute of Neurology of the University of Vienna J Neuroimmunol, 86: 213-217
  • Storch MK, Stefferl A, Brehm U, Weissert R, Wallström E, Kerschensteiner M, Olsson T, Linington C, Lassmann H (1998) Autoimmunity to myelin oligodendrocyte glycoprotein in rats mimics the spectrum of multiple sclerosis pathology Brain Pathol, 8: 681-694
  • Laman JD, Meurs KV, Schellekens MM, DeBoer M, Melchers B, Massacesi L, Lassmann H, Claassen E, t’Hart B (1998) Expression of accessory molecules and cytokines in acute EAE in marmoset monkeys (callizhrix jacchus) J Neuroimmunol, 86: 30-45
  • Andrä K, Lassmann H, Bittner R, Shorny S, Fässler R, Probst F, Wiche G (1998) Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle and heart cytoarchitecture Genes and Development, 11: 3143-3156
  • Lobell A, Weissert R, Storch MK, Svanholm C, DeGraaf KL, Lassmann H, Andersson R, Olsson T, Wigzell H (1998) Vaccination with DNA encoding an immunodominant myelin basic protein peptide targeted to Fc of IgG suppresses experimental autoimmune encephalomyelitis J Exp Med, 187: 1543-1548
  • Eugster HP, Frei K, Lassmann H, Fontana A (1998) Il-6 deficient mice resist myelin oligodendrocyte glycoprotein induced autoimmune encephalomyelitis despite intact T and B cell responses Eur. J. Immunol., 28: 2178-2187
  • Sahrbacher UC, Lechner F, Eugster HP, Frei K, Lassmann H, Fontana A (1998) Mice with an inactivation of the inducible nitric oxide sythase gene are susceptible to experimental autoimmune encephalomyelitis Eur. J. Immunol., 28: 1332-1338
  • Litzenburger T, Fässler R, Bauer J, Lassmann H, Linington C, Wekerle H, Iglesias A (1998) B lymphocytes producing demyelinating antibodies: Development and function in gene-trageted transgenic mice J Exp Med, 188: 169-180
  • Akassoglou K, Bauer J, Kassiotis G, Pasparakis M, Lassmann H, Kollias G, Probert L (1998) Oligodendrocyte apoptosis and primary demyelination induced by TNF/p55TNF receptor signaling in the CNS of transgenic mice models of chronic and acute multiple sclerosis Am.J.Pathol., 153: 801-813
  • t’Hart B, Bauer J, Muller HJ, Melchers B, Nicolay K, Brok H, Bontrop RE, Lassmann H, Massacesi L (1998) Histopathological characterization of magnetic resonance imaging-detectable brain white matter lesions in a primate model of multiple sclerosis. A correlative study in the experimental autoimmune ence Am.J.Pathol., 153: 649-663
  • Weissert R, Wallström E, Storch MK, Stefferl A, Lorentzen J, Lassmann H, Linington C, Olsson T (1998) MHC haplotype dependent regulation of MOG-induced EAE in rats J Clin Invest, 102: 1265-1273
  • Kääb, G., Haarmann, I., Wekerle, H., and Bradl, M (1998) The myelin basic protein-specific T cell repertoire in Lewis rats: T cell receptor diversity is influenced both by intrathymic milieu and by extrathymic peptide presentation Eur. J. Immunol., 28: 1499-1506
  • Bauer, J., Bradl, M., Hickey, W.F., Forss-Petter, S., Breitschopf, H., Linington, C., Wekerle, H., and Lassmann, H (1998) T cell apoptosis in inflammatory brain lesions. Destruction of T cells does not depend on antigen recognition Am.J.Pathol., 153: 715-724

1998 Reviews

  • Gatterbauer B., Neisser A., Bernheimer H., Schwerer B (1998) Antiglycosphingolipid immune responses in neurology: The Vienna experience with isotypes, subclasses, and disease Ann New York Acad Sci, 845: 353-362

1998 Books

  • Compston A, Ebers G, Lassmann H, McDonald I, Matthews B and Wekerle H (eds.) (1998) McAlpine's Multiple Sclerosis, 3rd Edition. , Churchill Livingstone, Philadelphia

1997 Original Articles

  • Rinner W, Pifl C, Lassmann H, Hörtnagl H (1997) Induction of apoptosis in vitro and in vivo by the cholinergic neurotoxin ethylcholine aziridinium Neuroscience, 79: 535-542
  • Stühler A, Flory E, Wege H, Lassmann H, Wege H (1997) No evidence for quasispezies populations during persistence of coronavirus mouse hepatitis virus JHM: sequence conservation within the surface glycoprotein gene S in Lewis rats J Gen Virol, 78: 747-756
  • Kojima K, Reindl M, Lassmann H, Wekerle H, Linington C (1997) The thymus and self-tolerance: co-existence of encephalitogenic S-100ß-specific T cells and their nominal autoantigen in normal adult rat thymus. Int Immunol, 9: 897-904
  • Berger T, Weerth S, Kojima K, Linington C, Wekerle H, Lassmann H (1997) Experimental autoimmune encephalomyelitis: The antigen specificity of T-lymphocytes determines the topography of lesions in the central and peripheral nervous system. Lab Invest, 76: 355-364
  • Bajramovic JJ, Lassmann H, VanNoort JM (1997) Expression of alphaB-crystallin in glia cells during lesional development in multiple sclerosis. J Neuroimmunol, 78: 143-151
  • Gold R, Hartung HP, Lassmann H (1997) T-cell apoptosis in autoimmune diseases: termination of inflammation in the nervous system and other sites with specialized immune-defense mechanisms. Trends Neurosci, 20: 399-404
  • Pouly S, Storch MK, Matthieu JM, Lassmann H, Monnet.Tschudi F, Honegger P (1997) Demyelination induced by protein kinase C-activating tumor promotors in aggregating brain cell cultures. J Neurosci Res, 49: 121-132
  • Brück W, Bitsch A, Kolenda H, Brück Y, Stiefel M, Lassmann H (1997) Inflammatory central nervous system demyelination: Correlation of magnetic resonance imaging findings with lesion pathology. Ann Neurol, 42: 783-793
  • Forss-Petter S, Werner H, Berger J, Lassmann H, Molzer B, Schwab MH, Bernheimer H, Zimmermann F, Nave KA (1997) Targeted inactivation of the X-linked adrenoleucodystrophy gene in mice. J Neurosci Res, 50: 829-843
  • Malpiero U, Frei K, Spanaus KS, Agresti C, Lassmann H, Hahne M, Tschopp J, Eugster HP, Fontana A (1997) Myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis is chronic relapsing in perforin knockout mice, but monophasic in Fas and Fas ligand-deficient lpr and gld mice. Eur. J. Immunol., 27: 3151-3160
  • Neisser A., Bernheimer H., Berger T., Moran A.P., Schwerer B (1997) Serum antibodies against gangliosides and Campylobacter jejuni lipopolysaccharides in Miller Fisher syndrome Infect Immun, 65: 4038-4042

1997 Reviews

  • Klinkert WEF, Kojima K, Lesslauer W, Rinner W, Lassmann H, Wekerle H (1997) TNF-alpha receptor fusion protein prevents experimental autoimmune encephalomyelitis and demyelination in Lewis rats: an overview J Neuroimmunol, 72: 163-168
  • Lassmann H, Brück W, Lucchinetti C, Rodriguez M (1997) Remyelination in multiple sclerosis Mult Scler, 3: 133-136

1996 Original Articles

  • Adelmann M, Wood J, Benzel I, Fiori P, Lassmann H, Matthieu JM, Gardinier MV, Dornmair K, Linington C (1996) The N-terminal domain of the myelin oligodendrocyte glycoprotein (MOG) induces acute demyelinating experimental autoimmune encephalomyelitis in the Lewis rat J Neuroimmunol, 63: 17-27
  • Schlüter D, Chahoud S, Lassmann H, Schumann A, Hof H, Dekert-Schlüter M (1996) The intracerebral lesions in murine listeria monocytogenes meningoencephalitis J Neuropath Exp Neurol, 55: 14-24
  • Simonova Z, Svoboda J, Orkand P, Bernard CCA, Lassmann H, Sykova E (1996) Changes in extracellular space volume and tortuosity in the spinal cord of Lewis rats with experimental autoimmune encephalomyelitis Physiol Res, 45: 11-22
  • Brück Y, Brück W, Kretschmar HA, Lassmann H (1996) Evidence of neuronal apotosis in pontosubicular neuronal necrosis Neuropathol Appl Neurobiol, 22: 23-29
  • Storch MK, Fischer-Colbrie R, Smith T, Rinner WA, Hickey WF, Cuzner ML, Winkler H, Lassmann H (1996) Co-localization of secretoneurin imunoreactivity and macrophage infiltration in the lesions of experimental autoimmune encephalomyelitis Neuroscience, 71: 885-893
  • Storch MK, Fischer-Colbrie R, Smith T, Rinner WA, Hickey WF, Cuzner ML, Winkler H, Lassmann H (1996) Co-localization of secretoneurin imunoreactivity and macrophage infiltration in the lesions of experimental autoimmune encephalomyelitis J Cell Sci., 71: 885-893
  • Morrissey SP, Stodal H, Zettl U, Simonis C, Jung S, Kiefer R, Lassmann H, Hartung HP, Haase A, Toyka KV (1996) In vivo MRI and its histological correlates in acute adoptive transfer experimental allergic encephalomyelitis. Quantification of inflammation and oedema Brain, 119: 239-248
  • Gold R, Schmied M, Tontsch U, Hartung H P, Wekerle H, Toyka K V, Lassmann H (1996) Antigen presentation by astrocytes primes rat T lymphocytes for apoptotic cell death: a model for T cell apoptosis in vivo Brain, 119: 651-659
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  • Smith T, Schmied M, Hewson AK, Lassmann H, Cuzner ML (1996) Apoptosis of T-cells and macrophages in the nervous system of intact and adrenalectomized Lewis rats during experimental allergic encephalomyelitis J Autoimmun, 9: 167-174
  • Brück W, Sommermeier N, Bergmann M, Zettl U, Goebel HH, Kretschmar HA, Lassmann H (1996) Macrophages in multiple sclerosis Immunobiology, 195: 588-600
  • Hainfellner JA, Kristoferitsch W, Lassmann H, Bernheimer H, Neisser A, Drlicek M, Beer F, Budka H (1996) T cell mediated ganglionitis associated with acute sensory neuronopathy Ann Neurol, 39: 543-547
  • Lucchinetti CF, Brück W, Rodriguez M, Lassmann H (1996) Distinct patterns of multiple sclerosis pathology indicates heterogeneity in pathogenesis Brain Pathol, 6: 259-274
  • Trieb K, Ransmayr G, Sgonc R, Lassmann H, Grubeck-Loebenstein B (1996) APP peptides stimulate lymphocyte proliferation in normals, but not in patients with Alzheimer’s disease. Neurobiol Aging, 17: 541-547
  • Meinl E, Hoch RM, Dornmair K, Malefyt R de W, Bontrop RE, Jonker M, Lassmann H, Hohlfeld R, Wekerle H, ‘t Hart BA (1996) Encephalitogenic potential of myelin basic protein-specific T cells isolated from normal rhesus macaques Am.J.Pathol., 150: 445-453
  • Schneider C, Gold R, Dalakas MC, Schmied M, Lassmann H, Toyka KV, Hartung HP (1996) MHC Class-I-mediated cytotoxicity does not induce apoptosis in muscle fibers nor in inflammatory T cells: Studies in patients with polymyositis, dermatomyositis and inclusion body myositis J Neuropath Exp Neurol, 55: 1205-1209
  • Salvati S, Sanchez M, Campeggi LM, Suchanek G, Breitschopf H, Lassmann H (1996) Accelerated myelinogenesis by dietary lipids in rat brain J Neurochem, 67: 1744-1750
  • Barac-Latas V, Suchanek G, Breitschopf H, Stuehler A, Wege H, Lassmann H (1996) Patterns of oligodendroglia pathology in coronavirus induced subacute demyelinating encephalomyelitis in the Lewis rat Glia, 19: 1-12
  • Lassmann H, Bartsch U, Montag D, Schachner M (1996) Dying-back oligodendrogliopathy: a late sequel of myelin-associated glycoprotein deficiency Glia, 19: 104-110
  • Jaquet V, Gow A, Tosic M, Suchanek G, Breitschopf H, Lassmann H, Lazzarini RA, Matthieu JM (1996) An antisense strategy to inhibit the myelin oligodendrocyte glycoprotein synthesis Mol Brain Res, 43: 333-337
  • Morrissey SP, Deichmann R, Syha J, Simonis C, Zettl U, Archelos JJ, Jung S, Stodahl H, Lassmann H, Toyka KV, Haase A, Hartung HP (1996) Partial inhibition of AT-EAE by an antibody to ICAM-1: clinico-histological and MRI studies J Neuroimmunol, 69: 85-93
  • Kääb, G., Brandl, G., Marx, A., Wekerle, H., and Bradl, M (1996) The myelin basic protein specific T cell repertoire in (transgenic) Lewis rat / SCID mouse chimeras: preferential vß8.2 T cell receptor usage depends on an intact Lewis thymic microenvironment Eur. J. Immunol., 26: 981-988

1996 Reviews

  • Bradl, M., and Linington, C (1996) Animal models of demyelination Brain Pathol, 6: 303-311
  • Bradl M (1996) Immune control of the brain Springer Sem Immun, 18: 35-49
  • Wekerle, H., Bradl, M., Linington, C., Kääb, G., and Kojima K (1996) The shaping of the brain-specific T lymphocyte repertoire in the thymus Immunol Rev, 149: 231-242

1995 Original Articles

  • HainfellnerJA, Pilz P, Lassmann H, Ladurner G, Budka H (1995) Diffuse Lewy body disease as substrate of primary lateral sclerosis J Neurol, 242: 59-63
  • Rössler K, Suchanek G, Breitschopf H, Kitz K, Matula C, Lassmann H, Koos WT (1995) Detection of TNFalpha protein and mRNA in human glial brain tumors comparing immunohistochemistry and in situ hybridization with molecular probes J Neurosurg, 83: 291-297
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  • Barac-Latas V, Wege H, Lassmann H (1995) Apoptosis of T Lymphocytes in Coronavirus induced Encephalomyelitis Regional Immunology, 6: 355-357
  • Rinner W, Bauer J, Schmidts M, Lassmann H, Hickey W F (1995) Resident microglia and hematogenous macrophages as phagocytes in adoptively transferred experimental autoimmune encephalomyelitis: an investigation using rat radiation bone marrow chimeras Glia, 14: 257-266
  • van Noort J M, van Sechel A C, Bajramovic J, El Ouagmiri M, Polman C H, Lassmann H, Ravid R (1995) A novel candidate autoantigen in multiple sclerosis: alpha-B-crystallin, a small heat shock protein Nature, 798-801
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  • Lorentzen JC, Issazadeh S, Storch M, Mustafa MI, Lassmann H, Linington C, Klareskog L, Olsson T (1995) Protracted, relapsing and demyelinating experimental autoimmune encephalomyelitis in DA rats immunized with syngeneic spinal cord and incomplete adjuvant J Neuroimmunol, 63: 193-205
  • Brück W, Porada Ph, Poser S, Rieckmann P, Hanefeld F, Kretschmer HA, Lassmann H (1995) Monocyte/macrophage differentiation in early multiple sclerosis Ann Neurol, 38: 788-796
  • Bauer J, Huitinga I, Zhao W, Lassmann H, Hickey WF, Dijkstra CE (1995) The role of macrophages, perivascular cells and microglia cells in the pathogenesis of experimental autoimmune encephalomyelitis Glia, 15: 437-446
  • Sykova E, Svoboda J, Simonova Z, Lehmenkühler A, Lassmann H (1995) X-irradiation induced changes in the diffusion parameters of the developing brain Neuroscience, 70: 597-610
  • Schmitt TL, Steiner E, Klingler P, Lassmann H, Grubeck-Loebenstein B (1995) Thyroid epithelial cells produce amounts of the Alzheimer ß-amyloid precursor protein (APP) and generate potentially amyloidogenic fragments J Clin Endocrinol Metab, 80: 3513-3519

1995 Reviews

  • Bradl M (1995) Autoimmunkrankheiten BiuZ, 25: 374-379

1995 Book Chapters

  • Lassmann H (1995) Pathology and experimental models. In: Kesselring, J&uuml;rg (ed.), Multiple Sclerosis; 3rd English Edition Kohlhammer, Stuttgart
  • Lassmann H, Vass K (1995) Inflammation in the nervous system. In: Mohr, JP and Gauthier, JC (eds), Adult Clinical Neurology Churchill Livingstone

1993 Original Articles

  • Larue, L., Dougherty, N., Bradl, M., and Mintz, B. (1993) Melanocyte culture lines from Tyr-SV40E transgenic mice: models for the molecular genetic evolution of malignant melanoma Oncogene, 8: 523-531

1993 Book Chapters

  • Lassmann H (1993) Pathologische Anatomie und experimentelle Modelle. In: Kesselring, J&uuml;rg (ed.), Multiple Sklerose, 2nd Edition Kohlhammer, Stuttgart: 18-45

1991 Original Articles

  • Bradl, M., Klein-Szanto, A., Porter, S., and Mintz, B (1991) Malignant melanoma in transgenic mice Proc Natl Acad Sci USA, 88: 164-168
  • Klein-Szanto, A., Bradl, M., Porter, S., and Mintz, B (1991) Melanosis and associated tumors in transgenic mice Proc Natl Acad Sci USA, 88: 169-173
  • Mintz, B. and Bradl, M (1991) Mosaic expression of a tyrosinase fusion gene in albino mice yields a heritable striped coat color pattern in transgenic homozygotes Proc Natl Acad Sci USA, 88: 9643-9647
  • Bradl, M., Larue, L., and Mintz, B (1991) Clonal coat color variation due to a transforming gene expressed in melanocytes of transgenic mice Proc Natl Acad Sci USA, 88: 6447-6451

1989 Original Articles

  • Bradl, M., Schmid, M., and Wekerle, H (1989) Clonotypic chromosomal aberrations in long term lines of myelin specific rat T lymphocytes J Neuroimmunol, 24: 95-104

1989 Book Chapters

  • Lassmann H (1989) Pathologische Anatomie und experimentelle Modelle. In: Kesselring, J&uuml;rg (ed.), Multiple Sklerose Kohlhammer, Stuttgart: 18-43

1988 Original Articles

  • Linington, C., Bradl, M., Lassmann, H., Brunner, C., and Vass, K. (1988) Augmentation of demyelination in rat acute allergic encephalomyelitis by circulating mouse monoclonal antibodies directed against a myelin/oligodendrocyte glycoprotein Am.J.Pathol., 130: 443-454
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  • Lassmann, H., Brunner, C., Bradl, M., and Linington, C (1988) Experimental allergic encephalomyelitis: The balance between encephalitogenic T lymphocytes and demyelinating antibodies determines size and structure of demyelinated lesions Acta Neuropathol, 75: 566-576

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