Skip to main content
English

Publikationen

  1. Zentrum für Hirnforschung
  2. Unsere Abteilungen
  3. Abteilung für Neuroimmunologie
  4. Research Labs
  5. Bauer Lab
  6. Publikationen

Last year | Last five years | All

2024202320222021202020192018201720162015201420132012201120102009200820072006200520042003

2024 Original Articles

  • Boutou A, Roufagalas I, Politopoulou K, Tastsoglou S, Abouzeid M, Skoufos G, Verdu de Juan L, Ko J, Kyrargyri V, Hatzigeorgiou A, Barnum C, Tesi R, Bauer J, Lassmann H, Johnson M, Probert L (2024) Microglia regulate cortical remyelination via TNFR1-dependent phenotypic polarization Cell Rep, 43 (11): 114894
  • Winklehner M, Wickel J, Gelpi E, Brämer D, Rauschenberger V, Günther A, Bauer J, Serra A, Jauk P, Villmann C, Höftberger R, Geis C (2024) Progressive Encephalomyelitis With Rigidity and Myoclonus With Glycine Receptor and GAD65 Antibodies Neurol Neuroimmunol Neuroinflamm, 11 (6): e200298
  • Bien C, Rada A, Mertens M, Bien C, Bauer J, Hagemann A, Woermann F (2024) LGI1 encephalitis: potentially complement-activating anti-LGI1-IgG subclasses 1/2/3 are associated with the development of hippocampal sclerosis J Neurol, 271 (9): 6325-6335
  • Roll W, Bauer J, Dik A, Mueller C, Backhaus P, Räuber S, Zinnhardt B, Gallus M, Wimberley C, Körtvelyessy P, Schindler P, Stenzel W, Elger C, Becker A, Lewerenz J, Wiendl H, Meuth S, Schäfers M, Melzer N (2024) 18F-DPA-714-PET-MRI reveals pronounced innate immunity in human anti-LGI1 and anti-CASPR2 limbic encephalitis J Neurol, 271 (6): 3653-3659
  • Beliën J, Swinnen S, D’hondt R, de Juan L, Dedoncker N, Matthys P, Bauer J, Vens C, Moylett S, Dubois B (2024) CHIT1 at diagnosis predicts faster disability progression and reflects early microglial activation in multiple sclerosis Nat Commun, 15 (1): 5013
  • Steinmaurer A, Riedl C, König T, Testa G, Köck U, Bauer J, Lassmann H, Höftberger R, Berger T, Wimmer I, Hametner S (2024) The relation between BTK expression and iron accumulation of myeloid cells in multiple sclerosis Brain Pathol, 34(5): e13240

2023 Original Articles

  • Gallus M, Roll W, Dik A, Barca C, Zinnhardt B, Hicking G, Mueller C, Naik V, Anstötz M, Krämer J, Rolfes L, Wachsmuth L, Pitsch J, van Loo K, Räuber S, Okada H, Wimberley C, Strippel C, Golombeck K, Johnen A, Kovac S, Groß C, Backhaus P, Seifert R, Lewerenz J, Surges R, Elger C, Wiendl H, Ruck T, Becker A, Faber C, Jacobs A, Bauer J, Meuth S, Schäfers M, Melzer N (2023) Translational imaging of TSPO reveals pronounced innate inflammation in human and murine CD8 T cell–mediated limbic encephalitis Sci Adv, 9 (23): eabq7595.
  • Martinović K, Bauer J, Kunze M, Berger J, Forss-Petter S (2023) Abcd1 deficiency accelerates cuprizone-induced oligodendrocyte loss and axonopathy in a demyelinating mouse model of X-linked adrenoleukodystrophy Acta Neuropathologica Communications, 11 (1): 98
  • Geeraerts T, Guilbeau-Frugier C, Garcia C, Memier V, Raposo N, Bonneville F, Gales C, Darcourt J, Voisin S, Ribes A, Piel-Julian M, Bounes F, Albucher J, Roux F, Izopet J, Telmon N, Olivot J, Sié P, Bauer J, Payrastre B, Liblau R (2023) Immunohistologic Features of Cerebral Venous Thrombosis Due to Vaccine-Induced Immune Thrombotic Thrombocytopenia Neurol Neuroimmunol Neuroinfl, 10 (4): e200127
  • Pegoretti V, Bauer J, Fischer R, Paro I, Douwenga W, Kontermann R, Pfizenmaier K, Houben E, Broux B, Hellings N, Baron W, Laman J, Eisel U (2023) Sequential treatment with a TNFR2 agonist and a TNFR1 antagonist improves outcomes in a humanized mouse model for MS J Neuroinflammation, 20 (1): 106
  • Gonzalez-Fierro C, Fonte C, Dufourd E, Cazaentre V, Aydin S, Engelhardt B, Caspi R, Xu B, Martin-Blondel G, Spicer J, Trapani J, Bauer J, Liblau R, Bost C (2023) Effects of a Small-Molecule Perforin Inhibitor in a Mouse Model of CD8 T Cell–Mediated Neuroinflammation Neurol Neuroimmunol Neuroinfl, 10 (4): e200117
  • Dorninger F, Kiss A, Rothauer P, Stiglbauer-Tscholakoff A, Kummer S, Fallatah W, Perera-Gonzalez M, Hamza O, König T, Bober M, Cavallé-Garrido T, Braverman N, Forss-Petter S, Pifl C, Bauer J, Bittner R, Helbich T, Podesser B, Todt H, Berger J (2023) Overlapping and Distinct Features of Cardiac Pathology in Inherited Human and Murine Ether Lipid Deficiency Int J Mol Sci, 24 (3): 1884
  • Zakani M, Nigritinou M, Ponleitner M, Takai Y, Hofmann D, Hillebrand S, Höftberger R, Bauer J, Lasztoczi B, Misu T, Kasprian G, Rommer P, Bradl M (2023) Paths to hippocampal damage in neuromyelitis optica spectrum disorders Neuropathol Appl Neurobiol, 49 (2)
    | Article (PDF) || Weblink |
  • Tröscher A, Mair K, de Juan L, Köck U, Steinmaurer A, Baier H, Becker A, Blümcke I, Finzel M, Geis C, Höftberger R, Mawrin C, von Oertzen T, Pitsch J, Surges R, Voges B, Weis S, Winklehner M, Woermann F, Bauer J, Bien C (2023) Temporal lobe epilepsy with GAD antibodies: neurons killed by T cells not by complement membrane attack complex Brain, 146(4): 1436-1452

2023 Reviews

  • Bien C, Bauer J (2023) What neuropathology teaches us about autoimmune encephalitides, autoimmune epilepsies, and encephalomyelitides Clin Neuropathol, 42(3): 87-92

2022 Original Articles

  • Weinhofer I, Buda A, Kunze M, Palfi Z, Traunfellner M, Hesse S, Villoria-Gonzalez A, Hofmann J, Hametner S, Regelsberger G, Moser A, Eichler F, Kemp S, Bauer J, Kühl J, Forss-Petter S, Berger J (2022) Peroxisomal very long-chain fatty acid transport is targeted by herpesviruses and the antiviral host response Commun Biol, 5 (1): 944
  • Winklehner M, Bauer J, Endmayr V, Schwaiger C, Ricken G, Motomura M, Yoshimura S, Shintaku H, Ishikawa K, Tsuura Y, Iizuka T, Yokota T, Irioka T, Höftberger R (2022) Paraneoplastic Cerebellar Degeneration With P/Q-VGCC vs Yo Autoantibodies Neurol Neuroimmunol Neuroinfl, 9 (4): e200006
  • Chuquisana O, Strippel C, Tröscher A, Baumgartner T, Rácz A, Keller C, Elger C, Melzer N, Kovac S, Wiendl H, Bauer J, Lünemann J (2022) Complement activation contributes to GAD antibody-associated encephalitis Acta Neuropathol, 144 (2): 381-383
  • Bernard-Valnet R, Frieser D, Nguyen X, Khajavi L, Quériault C, Arthaud S, Melzi S, Fusade-Boyer M, Masson F, Zytnicki M, Saoudi A, Dauvilliers Y, Peyron C, Bauer J, Liblau R (2022) Influenza vaccination induces autoimmunity against orexinergic neurons in a mouse model for narcolepsy Brain, : 145(6):2018-2030
  • Steinkellner H, Kempaiah P, Beribisky A, Pferschy S, Etzler J, Huber A, Sarne V, Neuhaus W, Kuttke M, Bauer J, Arunachalam J, Christodoulou J, Dressel R, Mildner A, Prinz M, Laccone F (2022) TAT-MeCP2 protein variants rescue disease phenotypes in human and mouse models of Rett syndrome Int J Biol Macromol, 209: 972-983
  • Frieser D, Pignata A, Khajavi L, Shlesinger D, Gonzalez-Fierro C, Nguyen X, Yermanos A, Merkler D, Höftberger R, Desestret V, Mair K, Bauer J, Masson F, Liblau R (2022) Tissue-resident CD8+ T cells drive compartmentalized and chronic autoimmune damage against CNS neurons Sci Transl Med, 14 (640)

2021 Original Articles

  • Tröscher A, Sakaraki E, Mair K, Köck U, Racz A, Borger V, Cloppenborg T, Becker A, Bien C, Bauer J (2021) T cell numbers correlate with neuronal loss rather than with seizure activity in medial temporal lobe epilepsy Epilepsia, 62 (6): 1343-1353
  • Zrzavy T, Endmayr V, Bauer J, Macher S, Mossaheb N, Schwaiger C, Ricken G, Winklehner M, Glatter S, Breu M, Wimmer I, Kovacs G, Risser D, Klupp N, Simonitsch‐Klupp I, Roetzer T, Rommer P, Berger T, Gelpi E, Lassmann H, Graus F, Dalmau J, Höftberger R (2021) Neuropathological variability within a spectrum of NMDAR‐encephalitis. Ann Neurol, : 2021 Sep 25. doi: 10.1002/ana.26223. Online ahead of print.
  • Rodríguez-Pascau L, Vilalta A, Cerrada M, Traver E, Forss-Petter S, Weinhofer I, Bauer J, Kemp S, Pina G, Pascual S, Meya U, Musolino P, Berger J, Martinell M, Pizcueta P (2021) The brain penetrant PPARγ agonist leriglitazone restores multiple altered pathways in models of X-linked adrenoleukodystrophy Sci Transl Med, 13 (596): eabc0555
  • Hamminger P, Marchetti L, Preglej T, Platzer R, Zhu C, Kamnev A, Rica R, Stolz V, Sandner L, Alteneder M, Kaba E, Waltenberger D, Huppa J, Trauner M, Bock C, Lyck R, Bauer J, Dupré L, Seiser C, Boucheron N, Engelhardt B, Ellmeier W (2021) Histone deacetylase 1 controls CD4+ T cell trafficking in autoinflammatory diseases J Autoimmun, 119: 102610
  • Zrzavy T, Schwaiger C, Wimmer I, Berger T, Bauer J, Butovsky O, Schwab J, Lassmann H, Höftberger R (2021) Acute and non-resolving inflammation associate with oxidative injury after human spinal cord injury Brain, 144(1): 144-161

2021 Reviews

  • Vilalta, A.; Berger, J; Forss-Petter, S.; Bauer, J.; Weinhofer, I.; Solà, Carme CSIC ORCID; Herrando-Grabulosa, Mireia; Navarro, Xavier; Martinell, M.; Pizcueta, P (2021) Leriglitazone decreases microglia activation and promotes protective phenotypes in several neuroinflammatory models of disease Glia,
  • Wiendl H, Gross C, Bauer J, Merkler D, Prat A, Liblau R (2021) Fundamental mechanistic insights from rare but paradigmatic neuroimmunological diseases Nat Rev Neurol, 17 (7): 433-447

2020 Original Articles

  • Zierfuss B, Weinhofer I, Kühl J, Köhler W, Bley A, Zauner K, Binder J, Martinović K, Seiser C, Hertzberg C, Kemp S, Egger G, Leitner G, Bauer J, Wiesinger C, Kunze M, Forss-Petter S, Berger J (2020) Vorinostat in the acute neuroinflammatory form of X-linked adrenoleukodystrophy Ann Clin Transl Neurol, 7 (5): 639-652
  • Kuehn J, Scheuerle A, Bauer J, Becker A, Wirtz R, Lewerenz J (2020) A 64‐Year‐Old Patient With a Mesiotemporal Mass and Symptomatic Epilepsy Brain Pathol, 30 (2): 413-414
  • Malviya M, Saoudi A, Bauer J, Fillatreau S, Liblau R (2020) Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells J Autoimmun, 108: 102401

2019 Original Articles

  • Gross C, Meyer C, Bhatia U, Yshii L, Kleffner I, Bauer J, Tröscher A, Schulte-Mecklenbeck A, Herich S, Schneider-Hohendorf T, Plate H, Kuhlmann T, Schwaninger M, Brück W, Pawlitzki M, Laplaud D, Loussouarn D, Parratt J, Barnett M, Buckland M, Hardy T, Reddel S, Ringelstein M, Dörr J, Wildemann B, Kraemer M, Lassmann H, Höftberger R, Beltrán E, Dornmair K, Schwab N, Klotz L, Meuth S, Martin-Blondel G, Wiendl H, Liblau R (2019) CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome Nat Commun, 10 (1): 5779
  • Yshii L, Pignolet B, Mauré E, Pierau M, Brunner-Weinzierl M, Hartley O, Bauer J, Liblau R (2019) IFN-γ is a therapeutic target in paraneoplastic cerebellar degeneration JCI Insight, 4 (7)
  • Bernard-Valnet R, Cobo-Calvo A, Siegfried A, Marasescu R, Bonnan M, Ballan G, Ellie E, Bauer J, Uro-Coste E, Marignier R, Brassat D (2019) Paraneoplastic neuromyelitis optica and ovarian teratoma: A case series Mult Scler Relat Disord., 31: 97-100
  • Tröscher A, Wimmer I, Quemada-Garrido L, Köck U, Gessl D, Verberk S, Martin B, Lassmann H, Bien C, Bauer J (2019) Microglial nodules provide the environment for pathogenic T cells in human encephalitis Acta Neuropathol, 137(4): 137(4):619-635

2018 Original Articles

  • Kap Y, Bus-Spoor C, van Driel N, Dubbelaar M, Grit C, Kooistra S, Fagrouch Z, Verschoor E, Bauer J, Eggen B, Harmsen H, Laman J, ’t Hart B (2018) Targeted Diet Modification Reduces Multiple Sclerosis–like Disease in Adult Marmoset Monkeys from an Outbred Colony J Immunol, 201 (11): 3229-3243
  • Machado-Santos J, Saji E, Tröscher A, Paunovic M, Liblau R, Gabriely G, Bien C, Bauer J, Lassmann H (2018) The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells Brain, 141(7): 2066-2082
  • Wimmer I, Tröscher A, Brunner F, Rubino S, Bien C, Weiner H, Lassmann H, Bauer J (2018) Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples Sci Rep, 8 (1): 6351
    | Weblink |

2017 Original Articles

  • Gebauer C, Pignolet B, Yshii L, Mauré E, Bauer J, Liblau R (2017) CD4+ and CD8+ T cells are both needed to induce paraneoplastic neurological disease in a mouse model Oncoimmunology, 6 (2): e1260212
  • Dunham J, van de Vis R, Bauer J, Wubben J, van Driel N, Laman J, ‘t Hart B, Kap Y (2017) Severe oxidative stress in an acute inflammatory demyelinating model in the rhesus monkey PlosOne, 12 (11): e0188013
  • Tröscher A, Klang A, French M, Quemada-Garrido L, Kneissl S, Bien C, Pákozdy A, Bauer J (2017) Selective Limbic Blood–Brain Barrier Breakdown in a Feline Model of Limbic Encephalitis with LGI1 Antibodies Front Immunol, 8: 1364
  • Kitic M, Karram K, Israel N, Yogev N, Lacher S, Tang Y, Yigit H, Bauer J, Wanke F, Knezovic A, Trotter J, Kurschus F, Waisman A (2017) NG2 plays a role in neuroinflammation but is not expressed by immune cells Acta Neuropathol, 134 (2): 325-327
  • Popkirov S, Ayzenberg I, Hahn S, Bauer J, Denno Y, Rieckhoff N, Radzimski C, Hans V, Berg S, Roghmann F, Noldus J, Bien C, Skodda S, Wellmer J, Stöcker W, Krogias C, Gold R, Schlegel U, Probst C, Komorowski L, Miske R, Kleiter I (2017) Rho-associated protein kinase 2 (ROCK2): a new target of autoimmunity in paraneoplastic encephalitis Acta Neuropathologica Communications, 5 (1)
    | Supplement |
  • Dunham J, Bauer J, Campbell G, Mahad D, van Driel N, van der Pol S, ‘t Hart B, Lassmann H, Laman J, van Horssen J, Kap Y (2017) Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis J Neuropath Exp Neurol, 76(6): 467-478
  • Espitia Pinzon N, Sanz-Morello B, Brevé J, Bol J, Drukarch B, Bauer J, Baron W, van Dam A (2017) Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination Sci Rep, 7: 40995
  • Laukoter S, Rauschka H, Tröscher A, Köck U, Saji E, Jellinger K, Lassmann H, Bauer J (2017) Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis Acta Neuropathol, 133(4): 613-627

2017 Reviews

  • ’t Hart B, Dunham J, Faber B, Laman J, van Horssen J, Bauer J, Kap Y (2017) A B Cell-Driven Autoimmune Pathway Leading to Pathological Hallmarks of Progressive Multiple Sclerosis in the Marmoset Experimental Autoimmune Encephalomyelitis Model Front Immunol, 8: 804-
  • Bauer J, Becker A, Elyaman W, Peltola J, Rüegg S, Titulaer M, Varley J, Beghi E (2017) Innate and adaptive immunity in human epilepsies Epilepsia, 58: 57-68

2016 Original Articles

  • Bernard-Valnet R, Yshii L, Quériault C, Nguyen X, Arthaud S, Rodrigues M, Canivet A, Morel A, Matthys A, Bauer J, Pignolet B, Dauvilliers Y, Peyron C, Liblau R (2016) CD8 T cell-mediated killing of orexinergic neurons induces a narcolepsy-like phenotype in mice PNAS, 113 (39): 10956-10961
  • Yshii L, Gebauer C, Pignolet B, Mauré E, Quériault C, Pierau M, Saito H, Suzuki N, Brunner-Weinzierl M, Bauer J, Liblau R (2016) CTLA4 blockade elicits paraneoplastic neurological disease in a mouse model Brain, 139 (11): 2923-2934
  • Peneder T, Bauer J, Pifl C (2016) Apoptosis-inducing factor in nigral dopamine neurons: Higher levels in primates than in mice Movement Disorders, 31: 1729-1733
  • Burm S, Peferoen L, Zuiderwijk-Sick E, Haanstra K, ‘t Hart B, van der Valk P, Amor S, Bauer J, Bajramovic J (2016) Expression of IL-1β in rhesus EAE and MS lesions is mainly induced in the CNS itself J Neuroinflammation, 13 (1)
  • Ramadan A, Lucca L, Carrié N, Desbois S, Axisa P, Hayder M, Bauer J, Liblau R, Mars L (2016) In situ expansion of T cells that recognize distinct self-antigens sustains autoimmunity in the CNS Brain, : aww032
    | Article (PDF) |
  • Dunham J, Lee L, van Driel N, Laman J, Ni I, Zhai W, Tu G, Lin J, Bauer J, ‘t Hart B, Kap Y (2016) Blockade of CD127 Exerts a Dichotomous Clinical Effect in Marmoset Experimental Autoimmune Encephalomyelitis J Neuroimmune Pharmacol, 11 (1): 73-83

2016 Reviews

  • Martin-Blondel G, Brassat D, Bauer J, Lassmann H, Liblau R (2016) CCR5 blockade for neuroinflammatory diseases — beyond control of HIV Nat Rev Neurol, 12(2): 95-105
  • Bauer J, Lassmann H. (2016) Neuropathological Techniques to Investigate Central Nervous System Sections in Multiple Sclerosis Methods Mol Biol, 1304: 211-229

2016 Book Chapters

  • Bauer J, Bien C (2016) Neuropathology of autoimmune encephalitides. In: , Handbook of Clinical Neurology : 107-120

2015 Original Articles

  • Jagessar S, Heijmans N, Blezer E, Bauer J, Weissert R, ‘t Hart B (2015) Immune profile of an atypical EAE model in marmoset monkeys immunized with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund’s adjuvant J Neuroinflammation, 12 (1): 169
  • Höftberger R, Leisser M, Bauer J, Lassmann H (2015) Autoimmune encephalitis in humans: how closely does it reflect multiple sclerosis ? Acta Neuropathologica Communications, 3 (1): 80
  • Kortvelyessy P, Bauer J, Stoppel C, Bruck W, Gerth I, Vielhaber S, Wiedemann F, Heinze H, Bartels C, Bien C (2015) Complement-associated neuronal loss in a patient with CASPR2 antibody-associated encephalitis Neurol Neuroimmunol Neuroinflamm, 2 (2): e75-e75. PK and JB share first authorship
  • Haanstra K, Dijkman K, Bashir N, Bauer J, Mary C, Poirier N, Baker P, Scobie L, 't Hart B, Vanhove B (2015) Selective Blockade of CD28-Mediated T Cell Costimulation Protects Rhesus Monkeys against Acute Fatal Experimental Autoimmune Encephalomyelitis J Immunol, 194 (4): 1454-1466
  • Licht-Mayer S, Wimmer I, Traffehn S, Metz I, Brück W, Bauer J, Bradl M, Lassmann H. (2015) Cell type-specific Nrf2 expression in multiple sclerosis lesions Acta Neuropathol, 130 (2): 263-277
  • Martin-Blondel G, Bauer J, Uro-Coste E, Biotti D, Averseng-Peaureaux D, Fabre N, Dumas H, Bonneville F, Lassmann H, Marchou B, Liblau RS, Brassat D. (2015) Therapeutic use of CCR5 antagonists is supported by strong expression of CCR5 on CD8+ T cells in progressive multifocal leukoencephalopathy-associated immune reconstitution inflammatory syndrome Acta Neuropathol, 129(3): 463-465
  • Skliris A, Papadaki O, Kafasla P, Karakasiliotis I, Hazapis O, Reczko M, Grammenoudi S, Bauer J, Kontoyiannis D (2015) Neuroprotection requires the functions of the RNA-binding protein HuR Cell Death Differ, 22(5): 703-718
    | Article (PDF) |

2015 Reviews

  • Bauer J, Gold R, Adams O, Lassmann H. (2015) Progressive multifocal leukoencephalopathy and immune reconstitution inflammatory syndrome (IRIS) Acta Neuropathol, 130(6): 751-764

2014 Original Articles

  • Nijland PG, Witte ME, van Het Hof B, van der Pol S, Bauer J, Lassmann H, van der Valk P, de Vries HE, van Horssen J. (2014) Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis Acta Neuropathologica Communications, 2(1): 170
  • Marlatt M, Bauer J, Aronica E, van Haastert E, Hoozemans J, Joels M, Lucassen P (2014) Proliferation in the Alzheimer Hippocampus Is due to Microglia, Not Astroglia, and Occurs at Sites of Amyloid Deposition Neural Plast, 2014: 1-12
  • Espitia Pinzon N, Stroo E, ‘t Hart B, Bol J, Drukarch B, Bauer J*, van Dam A* (2014) Tissue Transglutaminase in Marmoset Experimental Multiple Sclerosis: Discrepancy between White and Grey Matter PLoS One, 9 (6): e100574. *JB and AvD share senior authorship
  • Mars Lennart T., Mas Magali, Beaudoin Lucie, Bauer Jan, Leite-de-Moraes Maria, Lehuen Agnès, Bureau Jean-Francois, Liblau Roland S. (2014) Invariant NKT Cells Regulate the CD8 T Cell Response during Theiler's Virus Infection PLoS.ONE., 9 (1): e87717
  • Klang Andrea, Schmidt Peter, Kneissl Sibylle, Bagó Zoltán, Vincent Angela, Lang Bethan, Moloney Teresa, Bien Christian G., Halász Péter, Bauer Jan*, Pákozdy Ákos* (2014) IgG and Complement Deposition and Neuronal Loss in Cats and Humans With Epilepsy and Voltage-Gated Potassium Channel Complex Antibodies J Neuropath Exp Neurol, 73 (5): 403-413. *JB and AP share senior authorship
  • Schuh C, Wimmer I, Hametner S, Haider L, Van Dam AM, Liblau RS, Smith KJ, Probert L, Binder CJ, Bauer J, Bradl M, Mahad D, Lassmann H. (2014) Oxidative tissue injury in multiple sclerosis is only partly reflected in experimental disease models Acta Neuropathol, 128 (2): 247-266

2014 Reviews

  • Bien C, Bauer J (2014) Autoimmune Epilepsies Neurotherapeutics, 11 (2): 311-318
  • Varadkar Sophia, Bien Christian G, Kruse Carol A, Jensen Frances E, Bauer Jan, Pardo Carlos A, Vincent Angela, Mathern Gary W, Cross J Helen (2014) Rasmussen's encephalitis: clinical features, pathobiology, and treatment advances Lancet Neurology, 13 (2): 195-205

2014 Book Chapters

  • Bauer J, Lang B, Irani S, Vezzani A (2014) Immune Responses in the CNS in Epilepsy. In: Nicola Woodroofe and Sandra Amor, Neuroinflammation and CNS Disorders John Wiley & Sons, Ltd: 289-315

2013 Original Articles

  • Haanstra KG, Jagessar SA, Bauchet AL, Doussau M, Fovet CM, Heijmans N, Hofman SO, van Lubeek-Veth J, Bajramovic JJ, Kap YS, Laman JD, Touin H, Watroba L, Bauer J, Lachapelle F, Serguera C, 't Hart BA (2013) Induction of experimental autoimmune encephalomyelitis with recombinant human myelin oligodendrocyte glycoprotein in incomplete Freund's adjuvant in three non-human primate species J Neuroimmune Pharmacol, 8(5): 1251-1264
  • Pohl M, Kawakami N, Kitic M, Bauer J, Martins R, Fischer MT, Machado-Santos J, Mader S, Ellwart JW, Misu T, Fujihara K, Wekerle H, Reindl M, Lassmann H, Bradl M (2013) T cell-activation in neuromyelitis optica lesions plays a role in their formation Acta Neuropathologica Communications, : 1(1):85
  • Dauvilliers Y, Bauer J, Rigau V, Lalloyer N, Labauge P, Carlander B, Liblau R, Peyron C, Lassmann H. (2013) Hypothalamic Immunopathology in Anti-Ma-Associated Diencephalitis With Narcolepsy-Cataplexy Jama Neurol, 70(10): 1305-1310
  • Martin-Blondel G, Bauer J, Cuvinciuc V, Uro-Coste E, Debard A, Massip P, Delisle MB, Lassmann H, Marchou B, Mars LT, Liblau RS (2013) In situ evidence of JC virus control by CD8+ T cells in PML-IRIS during HIV infection Neurology, 81(11): 964-970
  • Fischer MT, Wimmer I, Höftberger R, Gerlach S, Haider L, Zrzavy T, Hametner S, Mahad D, Binder CJ, Krumbholz M, Bauer J, Bradl M, Lassmann H. (2013) Disease-specific molecular events in cortical multiple sclerosis lesions Brain, 136(Pt 6): 1799-1815
    | Weblink |
  • Kitic M, Hochmeister S, Wimmer I, Bauer J, Misu T, Mader S, Reindl M, Fujihara K, Lassmann H, Bradl M (2013) Intrastriatal injection of interleukin-1 beta triggers the formation of neuromyelitis optica-like lesions in NMO-IgG seropositive rats Acta Neuropathologica Communications, 1(1) : 5
  • Haanstra KG, Hofman SO, Lopes Estêvão DM, Blezer EL, Bauer J, Yang LL, Wyant T, Csizmadia V, 't Hart BA, Fedyk ER (2013) Antagonizing the a4b1 integrin, but not a4b7, inhibits leukocytic infiltration of the central nervous system in rhesus monkey experimental autoimmune encephalomyelitis J Immunol, 190(5): 1961-1973
  • Jagessar SA, Fagrouch Z, Heijmans N, Bauer J, Laman JD, Oh L, Migone T, Verschoor EJ, 't Hart BA. (2013) The Different Clinical Effects of Anti-BLyS, Anti-APRIL and Anti-CD20 Antibodies Point at a Critical Pathogenic Role of -Herpesvirus Infected B Cells in the Marmoset EAE Model J Neuroimmune Pharmacol, 8(3): 727-738
  • Pakozdy A, Halasz P, Klang A, Bauer J, Leschnik M, Tichy A, Thalhammer JG, Lang B, Vincent A. (2013) Suspected Limbic Encephalitis and Seizure in Cats Associated with Voltage-Gated Potassium Channel (VGKC) Complex Antibody J Vet Intern Med, 27(1): 212-214

2013 Reviews

  • Bien CG, Bauer J (2013) Pathophysiologie antikörperassoziierter ZNS-Erkrankungen Nervenarzt, 84: 466–470

2012 Original Articles

  • Jagessar SA, Heijmans N, Bauer J, Blezer EL, Laman JD, Migone TS, Devalaraja MN, 't Hart BA. (2012) Antibodies against human BLyS and APRIL attenuate EAE development in marmoset monkeys J Neuroimmune Pharmacol, 7(3): 557-570
  • Jagessar SA, Heijmans N, Bauer J, Blezer EL, Laman JD, Hellings N, 't Hart BA. (2012) B-cell depletion abrogates T cell-mediated demyelination in an antibody-nondependent common marmoset experimental autoimmune encephalomyelitis model J Neuropath Exp Neurol, 71(8): 716-728
  • Hochmeister S, Romauch M, Bauer J, Seifert-Held t, Weissert R, Linington C, Hartung HP, Fazekas F, Storch MK (2012) Re-expression of N-cadherin in remyelinating lesions of experimental inflammatory demyelination Exp. Neurol., 237: 70-77
  • Maj M, Milenkovic I, Bauer J, Berggard T, Veit M, Ilhan-Mutlu A, Wagner L, Tretter V (2012) Novel insights into the distribution and functional aspects of the calcium binding protein Secretagogin from studies on rat brain and primary neuronal cell culture Front Mol Neurosci, 5: Article 84
    | Supplement |
  • Bien CG, Vincent A, Barnett MH, Becker AJ, Blümcke I, Graus F, Jellinger KA, Reuss DE, Ribalta T, Schlegel J, Sutton I, Lassmann H, Bauer J. (2012) Immunopathology of autoantibody-associated encephalitides: clues for pathogenesis Brain, 135(Pt 5): 1622-1638
    | Article (PDF) |
  • Scheikl T, Pignolet B, Dalard C, Desbois S, Raison D, Yamazaki M, Saoudi A, Bauer J, Lassmann H, Hardin-Pouzet H, Liblau RS. (2012) Cutting Edge: Neuronal Recognition by CD8 T Cells Elicits Central Diabetes Insipidus J Immunol, 188 (10): 4731-4735
  • Jagessar SA, Heijmans N, Blezer EL, Bauer J, Blokhuis JH, Wubben JA, Drijfhout JW, van den Elsen PJ, Laman JD, Hart BA (2012) Unravelling the T-cell-mediated autoimmune attack on CNS myelin in a new primate EAE model induced with MOG(34-56) peptide in incomplete adjuvant Eur. J. Immunol., 42(1): 217-227
  • Jagessar SA, Gran B, Heijmans N, Bauer J, Laman JD, 't Hart BA, Constantinescu CS (2012) Discrepant Effects of Human Interferon-gamma on Clinical and Immunological Disease Parameters in a Novel Marmoset Model for Multiple Sclerosis J Neuroimmune Pharmacol, 7(1): 253-265

2012 Reviews

  • Bauer J, Vezzani A, Bien CG (2012) Epileptic encephalitis: the role of the innate and adaptive immune system Brain Pathol, 22(3): 412-421
    | Article (PDF) |

2011 Original Articles

  • Kap YS, Bauer J, Driel N, Bleeker WK, Parren PW, Kooi EJ, Geurts JJ, Laman JD, Craigen JL, Blezer E, 't Hart BA (2011) B-cell depletion attenuates white and gray matter pathology in marmoset experimental autoimmune encephalomyelitis J Neuropath Exp Neurol, 70(11): 992-1005
  • Van Strien ME, Baron W, Bakker EN, Bauer J, Bol JG, Brevé JJ, Binnekade R, Van Der Laarse WJ, Drukarch B, Van Dam AM (2011) Tissue transglutaminase activity is involved in the differentiation of oligodendrocyte precursor cells into myelin-forming oligodendrocytes during CNS remyelination Glia, 59(11): 1622-1634
  • Haider L, Fischer MT, Frischer JM, Bauer J, Höftberger R, Botond G, Esterbauer H, Binder CJ, Witztum JL, Lassmann H. (2011) Oxidative damage in multiple sclerosis lesions Brain, 134(Pt 7):: 1914-1924
  • Peneder TM, Scholze P, Berger ML, Reither H, Heinze G, Bertl J, Bauer J, Richfield EK, Hornykiewicz O, Pifl C (2011) Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic mice Neuroscience, 180: 280-292

2011 Reviews

  • Bien CG, Bauer J. (2011) Which pathomechanism damages the brain in antibody-associated CNS disease? Neurology, 77(5): 414-415

2010 Original Articles

  • Málaga-Diéguez L, Yang Q, Bauer J, Pankevych H, Freissmuth M, Nanoff C. (2010) Pharmacochaperoning of the A1 adenosine receptor is contingent on the endoplasmic reticulum Mol Pharmacol, 77(6): 940-952
  • Boucheron N, Sharif O, Schebesta A, Croxford A, Raberger J, Schmidt U, Vigl B, Bauer J, Bankoti R, Lassmann H, Epstein MM, Knapp S, Waisman A, Ellmeier W. (2010) The Protein Tyrosine Kinase Tec Regulates a CD44highCD62L- Th17 Subset J Immunol, 185(9):5111-5119
    | Article (PDF) |
  • Höftberger R, Kunze M, Voigtländer T, Unterberger U, Regelsberger G, Bauer J, Aboul-Enein F, Garzuly F, Forss-Petter S, Bernheimer H, Berger J, Budka H (2010) Peroxisomal Localization of the Proopiomelanocortin-Derived Peptides β-Lipotropin and β-Endorphin Endocrinology, 151 (10): 4801-4810
    | Article (PDF) |
  • Sharma R, Fischer MT, Bauer J, Felts PA, Smith KJ, Misu T, Fujihara K, Bradl M, Lassmann H. (2010) Inflammation induced by innate immunity in the central nervous system leads to primary astrocyte dysfunction followed by demyelination Acta Neuropathol, 120(2): 223-236
    | Article (PDF) |
  • Veto S, Acs P, Bauer J, Lassmann H, Berente Z, Setalo G Jr, Borgulya G, Sumegi B, Komoly S, Gallyas F Jr, Illes Z. (2010) Inhibiting poly(ADP-ribose) polymerase: a potential therapy against oligodendrocyte death Brain, 133(Pt 3):: 822-834
    | Article (PDF) |

2010 Book Chapters

  • Bien CC, Bauer J (2010) Rasmussen Encephalitis. In: Dale, Russell C. and Vincent, Angela, Inflammatory and Autoimmune Disorders of the nervous system in children MacKeith Press, London / Clinics in Developmental Medicine No.184-185: 207-226

2009 Original Articles

  • Bradl M, Misu T, Takahashi T, Watanabe M, Mader S, Reindl M, Adzemovic M, Bauer J, Berger T, Fujihara K, Itoyama Y, Lassmann H. (2009) Neuromyelitis optica: Pathogenicity of patient immunoglobulin in vivo Ann Neurol, 66(5): 630-643
    | Article (PDF) |
  • Fuchs P, Zorer M, Reipert S, Rezniczek GA, Propst F, Walko G, Fischer I, Bauer J, Leschnik MW, Luscher B, Thalhammer JG, Lassmann H, Wiche G. (2009) Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1C) in mice leads to reduced motor nerve conduction J Biol Chem, 284(39): 26502-9
    | Article (PDF) |
  • Derfuss T, Parikh K, Velhin S, Braun M, Mathey E, Krumbholz M, Kümpfel T, Moldenhauer A, Rader C, Sonderegger P, Pöllmann W, Tiefenthaller C, Bauer J, Lassmann H, Wekerle H, Karagogeos D et al (2009) Contactin-2/TAG-1-directed autoimmunity is identified in multiple sclerosis patients and mediates gray matter pathology in animals Proc Natl Acad Sci USA, 106(20): 8302-8307
    | Article (PDF) |

2009 Reviews

  • Bauer J, Bien CG (2009) Encephalitis and epilepsy Semin Immunopathol, 31(4) : 537-544
    | Article (PDF) |

2008 Original Articles

  • Kap YS, Smith P, Jagessar SA, Remarque E, Blezer E, Strijkers GJ, Laman JD, Hintzen RQ, Bauer J, Brok HP, 't Hart BA (2008) Fast progression of recombinant human myelin/oligodendrocyte glycoprotein (MOG)-induced experimental autoimmune encephalomyelitis in marmosets is associated with the activation of MOG34-56-specific cy J Immunol, 180(3): 1326-1337
  • Jagessar SA, Smith PA, Blezer E, Delarasse C, Pham-Dinh D, Laman JD, Bauer J, Amor S, 't Hart B (2008) Autoimmunity against myelin oligodendrocyte glycoprotein is dispensable for the initiation although essential for the progression of chronic encephalomyelitis in common marmosets J Neuropath Exp Neurol, 67(4): 326-40.
  • Bajramovic JJ, Brok HP, Ouwerling B, Jagessar SA, van Straalen L, Kondova I, Bauer J, Amor S, 't Hart BA, Ben-Nun A. (2008) Oligodendrocyte-specific protein is encephalitogenic in rhesus macaques and induces specific demyelination of the optic nerve Eur. J. Immunol., 38(5): 1452-1464
  • Hochmeister S, Zeitelhofer M, Bauer J, Nicolussi EM, Fischer MT, Heinke B, Selzer E, Lassmann H, Bradl M (2008) After injection into the striatum, in vitro-differentiated microglia- and bone marrow-derived dendritic cells can leave the central nervous system via the blood stream Am.J.Pathol., 173(6): 1669-1681
    | Article (PDF) || Supplement |
  • Saxena A*, Bauer J*, Scheikl T, Zapulla J, Audebert M, Desbois S, Waisman A, Lassmann H, Liblau RS, Mars LT (2008) Cutting edge: Multiple sclerosis-like lesions induced by effector CD8 T cells recognizing a sequestered antigen on oligodendrocytes J Immunol, 181(3): 1617-1621. *AS and JB share first authorship

2007 Original Articles

  • Mars LT, Bauer J, Gross DA, Bucciarelli F, Firat H, Hudrisier D, Lemonnier F, Kosmatopoulos K, Liblau RS (2007) CD8 T Cell Responses to Myelin Oligodendrocyte Glycoprotein-Derived Peptides in Humanized HLA-A*0201-Transgenic Mice J Immunol, 179: 5090-5098
  • Brok HP, Boven L, van MM, Kerlero de RN, Celebi-Paul L, Kap YS, Jagessar A, Hintzen RQ, Keir G, Bajramovic J, Ben-Nun A, Bauer J, Laman JD, Amor S, 't Hart BA (2007) The human CMV-UL86 peptide 981-1003 shares a crossreactive T-cell epitope with the encephalitogenic MOG peptide 34-56, but lacks the capacity to induce EAE in rhesus monkeys J Neuroimmunol, 182: 135-152
  • Blezer EL, Bauer J, Brok HP, Nicolay K, 't Hart BA (2007) Quantitative MRI-pathology correlations of brain white matter lesions developing in a non-human primate model of multiple sclerosis. NMR Biomed, 20: 90-103
  • Seifert T, Bauer J, Weissert R, Fazekas F, Storch MK (2007) Notch1 and its ligand Jagged1 are present in remyelination in a T-cell- and antibody-mediated model of inflammatory demyelination Acta Neuropathol, 113: 195-203
  • Rauschka H, Aboul-Enein F, Bauer J, Nobis H, Lassmann H, Schmidbauer M (2007) Acute cerebral white matter damage in lethal salicylate intoxication Neurotoxicology, 28: 33-37
  • Odoardi F, Kawakami N, Li Z, Cordiglieri C, Streyl K, Nosov M, Klinkert WE, Ellwart JW, Bauer J, Lassmann H, Wekerle H, Flügel A (2007) Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis Proc Natl Acad Sci USA, 104(3): 920-925
  • Adams RA, Bauer J, Flick MJ, Sikorski SL, Nuriel T, Lassmann H, Degen JL, Akassoglou K (2007) The fibrin-derived gamma377-395 peptide inhibits microglia activation and suppresses relapsing paralysis in central nervous system autoimmune disease J Exp Med, 204(3): 571-582
  • Kutzelnigg A, Faber-Rod JC, Bauer J, Lucchinetti CF, Sorensen PS, Laursen H, Stadelmann C, Brück W, Rauschka H, Schmidbauer M, Lassmann H (2007) Widespread demyelination in the cerebellar cortex in multiple sclerosis Brain Pathol, 17(1): 38-44
  • Bauer J, Elger CE, Hans VH, Schramm J, Urbach H, Lassmann H, Bien CG (2007) Astrocytes are a specific immunological target in Rasmussen's encephalitis Ann Neurol, 62(1): 67-80
  • Dumser M, Bauer J, Lassmann H, Berger J, Forss-Petter S (2007) Lack of adrenoleukodystrophy protein enhances oligodendrocyte disturbance and microglia activation in mice with combined Abcd1/Mag deficiency Acta Neuropathol, 114;6: 573-586
  • Marik C, Felts PA, Bauer J, Lassmann H, Smith KJ (2007) Lesion genesis in a subset of patients with multiple sclerosis: a role for innate immunity? Brain, 130;11: 2800-2815
    | Article (PDF) |

2006 Original Articles

  • Storch MK, Bauer J, Linington C, Olsson T, Weissert R, Lassmann H (2006) Cortical demyelination can be modeled in specific rat models of autoimmune encephalomyelitis and is major histocompatability complex (MHC) haplotype-related J Neuropath Exp Neurol, 65(12): 1137-1142
  • Hochmeister S., Grundtner R., Bauer J., Engelhardt B., Lyck R., Gordon G., Korosec T., Kutzelnigg A., Berger J., Bradl M., Bittner R.E., Lassmann H (2006) Dysferlin Is a New Marker for Leaky Brain Blood Vessels in Multiple Sclerosis J Neuropath Exp Neurol, 65: 855-865

2005 Original Articles

  • Bradl, M., Bauer, J., Flügel A., Wekerle H., and Lassmann, H (2005) Complementary contribution of CD4 and CD8 T lymphocytes to T cell infiltration of the intact and the degenerative spinal cord Am.J.Pathol., 166: 1441-1450

2005 Reviews

  • Bien CG, Bauer J. (2005) T-cells in human encephalitis Neuromolecular Med., : 7(3):243-53

2004 Original Articles

  • Tseveleki,-V; Bauer,-J; Taoufik,-E; Ruan,-C; Leondiadis,-L; Haralambous,-S; Lassmann,-H; Probert,-L (2004) Cellular FLIP (long isoform) overexpression in T cells drives Th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis J Immunol, 173(11): 6619-6926
  • Akassoglou,-K; Adams,-R-A; Bauer,-J; Mercado,-P; Tseveleki,-V; Lassmann,-H; Probert,-L; Strickland,-S (2004) Fibrin depletion decreases inflammation and delays the onset of demyelination in a tumor necrosis factor transgenic mouse model for multiple sclerosis Proc Natl Acad Sci USA, 101(17): 6698-6703
  • Xanthoulea,-S; Pasparakis,-M; Kousteni,-S; Brakebusch,-C; Wallach,-D; Bauer,-J; Lassmann,-H; Kollias,-G (2004) Tumor necrosis factor (TNF) receptor shedding controls thresholds of innate immune activation that balance opposing TNF functions in infectious and inflammatory diseases J Exp Med, 200 (3): 367-376
  • Aboul-Enein, F., Bauer, J., Klein, M., Schubart, A., Flügel, A., Ritter, T., Kawakami, N., Siedler, F., Linington, C., Wekerle, H., Lassmann, H., Bradl, M (2004) Selective and antigen dependent effects of myelin degeneration on central nervous system inflammation J Neuropath Exp Neurol, 63: 1284-1296

2003 Original Articles

  • Akassoglou K, Douni E, Bauer J, Lassmann H, Kollias G, Probert L (2003) Exclusive tumor necrosis factor (TNF) signaling by the p75TNF receptor triggers inflammatory ischemia in the CNS of transgenic mice Proc Natl Acad Sci USA, 100(2): 709-714
  • Cabarrocas,-J; Bauer,-J; Piaggio,-E; Liblau,-R; Lassmann,-H (2003) Effective and selective immune surveillance of the brain by MHC class I-restricted cytotoxic T lymphocytes Eur. J. Immunol., 33(5): 1174-1182

Partners and Support