Research Labs

The research questions target not only rare peroxisomal disorders such as X-linked adrenoleukodystrophy but also the role of peroxisomes in common neurodevelopmental and neurodegenerative disorders.

We study GABA-A receptor structure, function and pharmacology – project deal with e.g. the identification of novel binding sites, optimization of ligand selectivity, functional characterization of variants, or structure prediction.

We study the neurotransmitter receptors for GABA and Acetylcholine aiming to understand, which receptor subtypes actually exist, where they are distributed in the brain, and how they can be modulated pharmacologically.

Our research aims to investigate the influence of lipid metabolism on innate immunity and its connection to neurodegeneration and neuroinflammation.